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In conclusion, we show that CD8+ T cell responses contribute substantially to Ad26.COV2.S vaccine protection against SARS-CoV-2 replication in rhesus macaques. We speculate that CD8+ T cell responses may also contribute to virologic control following mRNA vaccination, although this has not yet been demonstrated.
Both humoral and cellular immune responses are likely important for vaccine protection against SARS-CoV-2 severe disease. It is likely that CD8+ T cell responses contribute more to protection against SARS-CoV-2 variants that partially evade NAb responses such as Delta and Omicron, as compared to protection against the original SARS-CoV-2 Wuhan or WA1/2020 strains.
Future studies should evaluate whether CD8+ T cell responses also contribute to SARS-CoV-2 vaccine protection in humans. Consistent with this perspective, approximately 70 investigators signed a letter to the FDA on April 21, 2022 encouraging the inclusion of T cell responses in addition to antibody titers for the evaluation of SARS-CoV-2 vaccines in humans, thus further raising awareness of the potential importance of cellular immunity for long-term vaccine protection, particularly against severe disease with SARS-CoV-2 variants
originally posted by: thethinkingman
This is complete proof you have ABSOLUTELY no clue about how the vaccines work.....
The mrna vaccines ALL use nanoparticle delivery. A. you have no clue about that obviously. If you have no clue about that most basic element of the vaccines, you obviously have absolutely nothing to say. You have literally less than no clue.
Atomic level???? errr....this guy doesnt even understand everything that is matter is made of atoms. So yeah it works at the atomic level...... the mrna is made of atoms....the spike proteins are made of atoms, your cells are made of atoms.....
How idiotic can you get and still argueing??? doesnt even realise how stupid they seem.
originally posted by: thethinkingman
Carcinogenicity
Carcinogenicity studies with BNT162b2 have not been conducted as the components of all vaccine constructs are lipids and RNA that arenot expected to have carcinogenic or tumorigenic potential. Carcinogenicity testing is generally not considered necessary to support the development and licensure of vaccine products for infectious diseases (WHO, 2005).
originally posted by: thethinkingman
They're displaying the most ignorant lack of knowledge possible.
originally posted by: Xtrozero
originally posted by: thethinkingman
They're displaying the most ignorant lack of knowledge possible.
So how many decades have you been in the professional field of vaccine research?
originally posted by: thethinkingman
You havent considered any of this cause you LITERALLY do not know anything about this.
originally posted by: v1rtu0s0
What's even crazier is that this information was leaked and not supposed to have gotten out. What other strange issues are occurring with players that isn't being reported? JJ Watt is a huge name in the NFL and this is not normal for an NFL athlete. But I think we all know why so many "strange" things are happening. Don't we?
The 33-year-old athlete was peeved someone leaked his personal information to the press.
“I went into A-Fib on Wednesday, had my heart shocked back into rhythm on Thursday and I’m playing today.” The Arizona Cardinals player said in a Twitter post on Sunday.
SOURCE
originally posted by: v1rtu0s0
Appeal to ignorance fallacy. You don't have to have credentials to understand something.
It will take you years to catch up to my level of knowledge starting from now and you researching literally for 16 hours a day."
They're displaying the most ignorant lack of knowledge possible.