Corona Virus Updates Part 6

From the Science Daily magazine, a summary of a study from France that says hydroxychloroquine doesn't help patients of Covid-19 and may in fact harm them.

The anti-inflammatory drug hydroxychloroquine does not significantly reduce admission to intensive care or death in patients hospitalised with pneumonia due to covid-19, finds a study from France published by The BMJ today.

A randomised clinical trial from China also published today shows that hospitalised patients with mild to moderate persistent covid-19 who received hydroxychloroquine did not clear the virus more quickly than those receiving standard care. Adverse events were higher in those who received hydroxychloroquine.

Taken together, the results do not support routine use of hydroxychloroquine for patients with covid-19.

Back when I was involved in "journal club" for a medical school (everyone selected and presented two articles a week to the group so that the group was able to keep up with the latest research without having to read every single publication that came into the library), I noticed that there would be coincidental clusters of articles during a health crisis.... and that these would later turn out to be key findings in a larger picture. So a single article on something is "interesting and to be observed", but when you get four or five of them from different sources and from people that aren't working together, it suggests something meaningful.

This is what's happening with "vitamin D" and Covid-19. It's also happening with hydroxychloroquine... but in a negative way (studies saying it's not as good as other drugs.)

And a retrospective study (combing back through case records to see what can be learned) of patients in Orange County, California, with severe Covid-19 infections who were put on respirators:

Improved survival outcome in SARs-CoV-2 (COVID-19) Acute Respiratory Distress Syndrome patients with Tocilizumab administration

Tocilizumab has showed up a few other times in recent research papers. It's not a cure, but *may* help patients recover.

a reply to: Byrd

Take a look at this.

NO MSM
NO NWO
NO WHO
NO TRUMP

It the closest web site dealing with the truth that I have found to date:

Servo

Sermo is a private social media network for physicians open to licensed M.D.s and D.O.s in the United States, and 149 other countries across Europe, North and South America, Africa, and English-speaking Oceania. Wikipedia

Largest Statistically Significant Study by 6,200 Multi-Country Physicians on COVID-19 Uncovers Treatment Patterns and Puts Pandemic in Context April 2, 2020 Sermo Reports on Hydroxychloroquine Efficacy, Rise in Prophylaxis Use; Over 80% Expect 2nd Outbreak New York, New York – April 2, 2020 – Widespread confusion, conflicting reports, inconsistent testing, and off-indication use of existing and experimental drugs has resulted in no single source of information from the frontlines. To create a centralized and dynamic knowledge base, Sermo, the largest healthcare data collection company and global social platform for physicians, leveraged its capabilities to publish results of a COVID-19 study with more than 6,200 physicians in 30 countries. The study was completed in three days. Data covers current treatment and prophylaxis options, timing to the outbreak peak, effectiveness of government responses, and much more. Results of the first wave can be found at sermo.com. Multiple study waves including a deeper dive into treatments will be conducted over the next several weeks, and Sermo is calling all physicians globally to participate. Key findings; Sermo Real Time Barometer*:

a reply to: Agit8dChop

Go to Servo!!!

Servo

Qatar launches world's toughest punishments with three years in jail and £45,000 fines for anyone not wearing a face mask as it battles one of globe's highest coronavirus infection rates

www.dailymail.co.uk...

Some news on Italy's Phase 2. In the last two weeks I've only been allowed to go back to work once a week. Travelling on trains and buses has been surreal, with limited seating and still deserted streets. Temperature checks are done before allowing people into my workplace.

Anyway, from tomorrow phase 2 kicks in and there's an easing of many restrictions, albeit with social distancing remaining paramount. Fingers crossed that people won't go crazy with this new "freedom" and cause a new wave of infection and second lockdown. Some of the following things will be staggered and gradually introduced over the next two weeks.

A few of the changes:

- Leaving home doesn't require paperwork, nor motive. The only limitation is to remain within one's Region (ie: Lazio, Lombardy, etc.)

- Parks are open, but patrolled.

- You can meet anyone you like, but mass congregating is not permitted.

- Exercise and some, non contact, sports allowed. Outdoor activities are ok. Some pools will also be able to open (not sure if they mean indoor ones as well).

- Schools remain closed for now.

- Stores and shopping centres can open if they respect the social distancing rules. One-way systems in place for entry/exit and generally moving around malls. Limited numbers of clients will be allowed to enter stores depending on size. All staff must wear PPE.

- Hairdressers can operate, but only by appointment and the customer must arrive at the appointed time to avoid loitering outside.

- There are other minor clauses to this new phase which I won't bore you with, but an important and difficult situation arises for restaurants, which are allowed to open...

Read about the plight of restaurants here:
How will we ever make people feel at home again, ask Italy's fearful trattorias

originally posted by: Waterglass
a reply to: Agit8dChop

Go to Servo!!!

Servo

Go to Servo!!!

You mean Sermo? Ok.

Survey says, for treatment of mild symptoms, 37% of those surveyed say that Hydroxychloroquine (Plaquenil) or Chloroquine is very effective or highly effective. Which means that 63% say that Hydroxychloroquine (Plaquenil) or Chloroquine is moderately effective, sligthly effective, or not effective. "Traditional Chinese Medicine" has the highest approval rating, at 67%.

Survey says, for treatment of hospitalized patients, 20% of those surveyed say that Hydroxychloroquine (Plaquenil) or Chloroquine is very effective or highly effective. Which means that 80% say that Hydroxychloroquine (Plaquenil) or Chloroquine is moderately, sligthly, or not effective. "Traditional Chinese Medicine" has the highest approval rating, at 63%.



Hydroxychloroquine (Plaquenil) and Chloroquine don't seem to stand out much in the survey in comparison to most other treatments.
app.sermo.com...

Numbers from around the world are taken from Worldometers for May 17th.

Spain - Pop: 44.6 M
277,719 Positive tests…….. or 1 out of 168 Spaniards
9.95% Deaths of positive tested
National Deaths (27,650) 1 per 1,688

Italy - Pop: 60.4 M
225,435 Positive tests….. or 1 out of 268 Italians
14.15 % Deaths of positive tested
National Deaths (31,908) 1 per 1,895

UK – Pop: 66.6 M
243,303 Positive tests….. or 1 out of 274 UKers
14.23 % Deaths of positive tested
National Deaths (34,636) 1 per 1,924

France – Pop: 67.0 M
179,569 Positive tests….. or 1 out of 373 French
15.653 % Deaths of positive tested
National Deaths (28,108) 1 per 2,383

Sweden – Pop: 10.2 M
30,143 Positive tests….. or 1 out of 339 Swedes
12.20 % Deaths of positive tested
National Deaths (3,679) 1 per 2,781

Denmark – Pop: 5.8 M
10,927 Positive tests….. or 1 out of 531 Danes
5.00 % Deaths of positive tested
National Deaths (547) 1 per 10,603

US - Pop: 330 M
1,515,311 Positive tests.... or 1 out of 218 Americans
5.96 % Deaths of positive tested
National Deaths 1 per 3,653

US death rates (2017):
1. Heart Disease …………….…………647,457 annual or 1,773 daily average
2. Cancer ……………………..……….….599,108 annual or 1,641 daily average
3. Accidents (unintentional injuries): 169,936 annual or 465 daily average
6. Alzheimer’s disease:…….……….121,404 annual or 332 daily average

COVID-19 ………………………………………. 90,332 (78 Day) or 1158 daily average

*** SURPASSED *****

7. Diabetes:………………………………….83,564 annual or 228 daily average
8. Influenza and Pneumonia …………55,562 annual or 152 daily average
9. Nephritis, nephrotic syndrome, and nephrosis:..50,633 annual or 138 daily average
10. Intentional self-harm (suicide):..47,173 annual or 129 daily average
X. Auto accidents ………………….………37,461 annual or 102 daily average
X. H1N1 2009 ESTIMATED (8,868 – 18,638) for 1 year or 24 – 50 daily average

originally posted by: Waterglass
a reply to: Byrd

Take a look at this.

NO MSM
NO NWO
NO WHO
NO TRUMP

I've been using MedRxIv, which is the preprint server for researchers. It's global and politically neutral.

It the closest web site dealing with the truth that I have found to date:

Servo

Quite interesting! I checked it out to make sure it was valid, and it certainly is what it claims to be.

The difference in these two sites is that SerMo (not "servo") is a social website similar to Facebook, but with articles and research on its members. It's not a preprint server that publishes medical research, but something more akin to what I see on the AARP site (a few articles, a lot of interaction and comment from members.) Research articles, while valid, suffer from the same kind of self-appointing as Facebook surveys or AARP surveys, etc... it's not the kind of pure enrollment research you'd seen elsewhere or the pure retrospective, but a self-selecting group of commenters and responders.

Which is okay, as long as the reader remembers that there may be some selection bias there.

The articles follow patterns similar to what I see on MedRxIv...for instance, this one from May 7 shows a high demand for Remdesivir and plasma. Hydrochloroquine is being used in a lot of places but, as per the article (and the research I cited) it's seen as better for patients that aren't hospitalized and doctors are concerned that it's not a very safe drug.

Still, another picture of the same data that I've been reporting on. Bookmarked, and thanks!

a reply to: checkmeout

Well said!

Elton and other private schools to which the rich send their kids are to remain closed. But state schools for kids as young as 5 and upwards are to open in 2 weeks time...

All the while the houses or Parliament and the House of Lords remain closed because it’s not yet safe for them...

What the hell does it take to finally make a populace overthrow their corrupt, murdering regime?

If they can get away with lies and hypocrisy on this level you have to worry about what that’ll embolden them to do to us next.

a reply to: Byrd

Is vitamin D good or bad? Should we take it in order to protect us or the opposite? Could you please elaborate? Thanks

Antiviral therapeutic approaches for human rhinovirus infections

Vitamin D shows up in this study about antivirals.

Studies have shown that deficiency in LL-37 in humans leads to an increased susceptibility to infection [73], and mice deficient in the murine cathelicidin (mCRAMP) also display an increased susceptibility to both bacterial and viral infections of the airway tract, skin, urinary tract and gut [74,75,76]. On the contrary, exogenous delivery of LL-37 in murine models offered enhanced clearance and reduced mortality in lethal influenza infection [77].

Cathelicidins have shown potent antiviral activity against a number of viruses (reviewed in [70]) but the exact mechanism of action is still not fully elucidated. It is clear that the underlying antiviral mechanism of cathelicidins appears to be partly due to direct effects on the virus envelope, and this has been extensively shown in in vitro studies. Both LL-37, and the murine cathelicidin mCRAMP, have shown the ability to damage the viral envelope of vaccinia virus, influenza A virus (IAV) and HSV [77,78,79,80]. LL-37 has also been shown to target viral envelope proteins inhibiting dengue virus entry into host cells [81].

Cathelicidin

Cathelicidin peptides have been isolated from many different species of mammals. Cathelicidins were originally found in neutrophils, but have since been found in many other cells including epithelial cells and macrophages after activation by bacteria, viruses, fungi, or the hormone 1,25-D, which is the hormonally active form of vitamin D.[7]

Numbers Update for Europe, and Elsewhere (No BNO) :







www.worldometers.info...

originally posted by: deccal
a reply to: Byrd

Is vitamin D good or bad? Should we take it in order to protect us or the opposite? Could you please elaborate? Thanks

It is not completely proven, but the data suggests that it's something that's low cost and can help. I posted two (out of several) papers I found on it, along with several reports that I felt were more anecdotal. It was enough to convince me to start taking a daily Vitamin D supplement. I picked up a cheap brand of gummies from the local pharmacy.

In Ireland they're giving supplements of Vitamin D to those at most risk (the elderly), hoping that if they get it, it will be less serious. Vitamin D does help in a number of body functions (here's an article about it) and it's said that people tend to be deficient in Vitamin D since we don't spend much time outdoors now.

This is one of those "couldn't hurt" moves... take a daily vitamin supplement -and/or- take a Vitamin D supplement (but don't OVERindulge in it with massive multiple doses.) At the worst it'll just help bone and immune systems support.

If you have some health problems, check with your doctor's office to see if it's okay to take the supplement. Alternatively, plan to spend 20 minutes or more outside every day if you can. Don't forget your sunscreen!

a reply to: McGinty

Its called Stockholm syndrome, A small little Island with to many people per square mile.

a reply to: anonentity

Its called Stockholm syndrome

No. You should ask Patty Hearst what Stockholm syndrome actually is.

originally posted by: anonentity
a reply to: McGinty

Its called Stockholm syndrome, A small little Island with to many people per square mile.

No offense, but I think you need to brush up on your geography. Stockholm is the capital of Sweden, one of the larger countries in Europe.

And (in the theme of this thread) their "lassez faire" approach to the pandemic has resulted in them having a higher rate of death than any other country in the EU... and higher than the rate of death for the US

Stockholm Syndrome is defined here

a reply to: Phage
not sure you read your source right
looks like those that treat patients 56% use Hydroxychloroquine (Plaquenil) or Chloroquine in the pre-ICU stages

Still puzzled no one mentions using zinc with it.

Please indicate which medications you are currently using to treat COVID-19 patients In the hospital (moderate-severe symptoms, excluding ICU patients).
Hydroxychloroquine (Plaquenil) or Chloroquine
56%
Azithromycin or similar antibiotics
54%
Tocilizumab (Actemra)
30%
Remdesivir
26%
Anti-HIV drugs (e.g. Lopinavir plus Ritonavir – Kaletra)
23%
Plasma from patients who have recovered from COVID-19 (convalescent plasma)
17%
Oseltamivir (Tamiflu)
12%
Zinc
11%
Gamma Globulin
9%
Favipiravir (Avigan)
8%
Acyclovir
8%
Interferon-beta
7%
Colchicine
6%
Ivermectin
5%
Sarilumab (Kevzara)
4%
Traditional Chinese Medicine
4%
Methotrexate
3%
N

a reply to: puzzled2

not sure you read your source right

About what? Specifically?
I was referring to the survey results regarding efficacy.

a reply to: Phage

So 56% of treatments are 4 time worst that the TCM which is only 4% used. Seems like lies lies and statistics to me. What are you trying to spread panic about treatment or hoax TCM herbal tea's.