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Originally posted by MikeNice81
reply to post by Mercurio
I read recently that they are considerring lowering it to 23.something. So how many more people would be dropped in to the overweight and obese categories?
I've got a friend that is 5'11" and 215lbs. His body fat percentage is about 6%. According to the BMI chart he is obese. However, he very obviously isn't. He works out 4 hours a day, runs marathons, and eats a completely organic diet. Yet, according to the government he is obese and unhealthy.
British researchers have found a gene they say is
linked to Type 2 diabetes and cholesterol levels and
serves as the master switch that controls the behavior
of other genes found within body fat. The discovery
could lead to obesity-related treatments in the future.
In a study published in the journal Nature Genetics,
the scientists highlight the key role fat plays in
metabolic illnesses such as obesity, heart disease,
high cholesterol and diabetes. If they can gain a
better understanding of how it all works, they may be
able to develop better drugs to treat these conditions.
In the United States, obesity-related diseases account
for nearly 10 percent of medical spending; an e
stimated $147 billion a year. As rates of obesity rise,
Type 2 diabetes has also approached epidemic levels
worldwide.
Lead researcher Tim Spector, Ph.D. of King's College
in London notes that there are a myriad of genetic
factors associated with metabolic illnesses but the
gene known as KLF14 is special because it acts as a
regulator for many other genes. "Obesity is caused by
a large number of genes acting together to increase
susceptibility. Although all of them are of small effect
on their own, by acting in concert in different ways
they can have a significant effect," he comments.
It was already known that KLF14 is connected to Type
2 diabetes and cholesterol levels but until now, the
extent of its role was a mystery. Spector's team
clarified its mechanism by examining over 20,000
genes biopsied from the subcutaneous fat of 800 UK
female twins and finding an association between
KLF14 and the activity of other distant genes found in
fat tissue. This proved KLF14's ability to control the
other gene's influence on a range of metabolic traits,
including body-mass index (obesity), cholesterol,
insulin and glucose levels and highlighted the strong
interconnections between these traits.
A copy of KLF14 is inherited from both parents as is
the case with all genes but only the mother's is active
-- a process called imprinting. That doesn't mean
your mother can be blamed exclusively for your
flabby arms and jiggly thighs since so many other
causes influence health and weight. Some genes are
even passed down from grandparents. And lifestyle
habits such as how much you eat and how little you
move place much of the responsibility for weight and
size on the individual.
This is the first major study to show how small
changes in one master regulator gene can cause a
cascade of other metabolic effects in other genes.
Spector says his team is working hard to understand
fully how this information can be used to improve
treatment of obesity-related health issues. It's
possible scientists may be able to switch the gene on
and off but the answer to whether that is possible is
at least a decade off.
Soure: habits such as how much you eat and how little you
move place much of the responsibility for weight and
size on the individual.
This is the first major study to show how small
changes in one master regulator gene can cause a
cascade of other metabolic effects in other genes.
Spector says his team is working hard to understand
fully how this information can be used to improve
treatment of obesity-related health issues. It's
possible scientists may be able to switch the gene on
and off but the answer to whether that is possible is
at least a decade off.
habits such as how much you eat and how little you
move place much of the responsibility for weight and
size on the individual.
This is the first major study to show how small
changes in one master regulator gene can cause a
cascade of other metabolic effects in other genes.
Spector says his team is working hard to understand
fully how this information can be used to improve
treatment of obesity-related health issues. It's
possible scientists may be able to switch the gene on
and off but the answer to whether that is possible is
at least a decade off.
Source: abcnews.go.com...
It really isn't that hard to lose weight.
There are people with glandular problems and diabetes that have a much harder time losing weight. For them I do have some amount of empathy. I don't think it is right to tax those type of people.
I do get tired of lazy people complaining that they can't lose weight while sitting at Dunkin' Donuts scarfing down a chocolate cherry danish and large coffee with six creamers.
The thing is Americans have been trained to not take responsibility for their actions. It is all of us to some extent. So, people ask the government to come in and take responsibility for them. Unfortunately they don't understand one simple thing, a government big enough to give you every thing you want is big enough to take it all away.