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Originally posted by squiz
"Levinthal's paradox is a thought experiment" wikipedia.
Cotranslational protein folding—fact or fiction?
Motivation: Experimentalists have amassed extensive evidence over the past four decades that proteins appear to fold during production by the ribosome. Protein structure prediction methods, however, do not incorporate this property of folding. A thorough study to find the fingerprint of such sequential folding is the first step towards using it in folding algorithms, so assisting structure prediction.
Results: We explore computationally the existence of evidence for cotranslational folding, based on large sets of experimentally determined structures in the PDB. Our perspective is that cotranslational folding is the norm, but that the effect is masked in most classes. We show that it is most evident in α/β proteins, confirming recent findings. We also find mild evidence that older proteins may fold cotranslationally. A tool is provided for determining, within a protein, where cotranslation is most evident.
Originally posted by Brasov
Originally posted by squiz
Very nice. Too true, there is no such thing as a simple life form.
What's your definition of life? To me, life is anything that can reproduce and change to adapt to its environment.
Now here' s a very simple life-form according to this definition that reproduces and evolves:
Artificial molecule evolves in the lab - life - 08 January 2009 - New Scientist
A new molecule that performs the essential func.tion of life - self-replication - could shed light on the origin of all living things. If that wasn't enough, the laboratory-born ribonucleic acid (RNA) strand evolves in a test tube to double itself ever more swiftly.
Self-Sustained Replication of an RNA Enzyme
Life-like evolution in a test tube | COSMOS magazine
Originally posted by sacgamer25
Why is it that everyone can look at an automobile and know that it could have never built itself, started itself, and reproduced itself? But when one looks at a single cell that is far more complex than an automobile they imagine it could have built itself, started itself, and reproduced itself. And I'm still waiting for my Toyota to evolve into a BMW.
Originally posted by sacgamer25
I'm still waiting for my Toyota to evolve into a BMW.
Originally posted by Brasov
The watchmaker fallacy is a self-refuting argument: if complex things must have been intelligently designed by something more complex than themselves, then anything posited as this complex designer (god) must also have been designed by something yet more complex.
Originally posted by sacgamer25
But this is where you are incorrect the creator lives outside the laws of the creation. Thus the creator also lives outside the bounds of time.
Originally posted by sacgamer25
You only know what you see and can test. Because you are bound by these principles does not bind the creator to these principles.
Originally posted by sacgamer25
This is not so most science agree that there was something prior to what we see that was not bound by the laws of what we see. Here is something for you to think about.
The singularity
No matter what route you take I would like you to consider a few things. First, all things had a beginning; science now calls this a singularity. Science has proven that the universe in its current state appears to both be expanding and dying.
Originally posted by Brasov
a creator is not needed to explain the observable universe, there are simpler explanations that don't invoke magic.
That's what this thread is about.edit on 12-1-2012 by Brasov because: (no reason given)
Originally posted by sacgamer25
String theory is fantasy if you weren’t sure, since it cannot be proven by math or observable science.
Originally posted by Brasov
Originally posted by sacgamer25
This is not so most science agree that there was something prior to what we see that was not bound by the laws of what we see. Here is something for you to think about.
The singularity
No matter what route you take I would like you to consider a few things. First, all things had a beginning; science now calls this a singularity. Science has proven that the universe in its current state appears to both be expanding and dying.
The discussion about the evolution of living beings is one topic. The discussions about the origins of the Universe and the origins of life (the first cell) are unrelated topics.
When defeated by evolutionists, creationists often switch topic and pretend they're discussing the same thing.
You can always open a thread about the origins of life or the origins of the Universe and we'll meet there, but please don't contaminate this thread.edit on 12-1-2012 by Brasov because: (no reason given)
Originally posted by sacgamer25
When confronted with origins, evolutionists always want to ignore that they simply have to say I don't know.
Originally posted by squiz
Loads of evidence = Cotranslational protein folding—fact or fiction?
Nope, not a single answer to any of the problems proposed in this thread. Not one. Just more unfounded "just so" stories.
Originally posted by squiz
I'm only interested in the scientific facts. Darwinism is refuted under close scientific scrutiny,
Originally posted by JohnPhoenix
I believe in Creationism and Evolution - because they can Both be valid.
Originally posted by JohnPhoenix
Science is just as much a religion as any if one is not willing to be objective and open minded - even open minded to the possibility that God exists.