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Originally posted by Barcs
Nope. Genetic changes and environment are the prime "mover of all things" in evolution.
Evolution is based on objective evidence. Creation is not. It really is THAT simple. I do say "I don't know" when asked what caused the universe or life on earth. Technically you should as well, but you don't. You are claiming your view of these events is fact when its faith.
And since it will never be "chance" - then the only logical conclusion is an Intelligent Entity! Jehovah God!
The evidence for evolution is gargantuan and undeniable.
It happened, we just don't know how. But we do know that life evolved and diversified into what we see today.
Originally posted by edmc^2
Yet the so called "God of the gaps" that evolutionists always ridicule is the ONLY logical and satisfactory answer to the question of the Origin of Life. Other than that the alternative is NOTHING.
That nothing created everything by chance events and thus evolutionists have no other explanation but to admit "we don't know".
This is the legacy of evolution theory - its very foundation is nothingness.
As for the Origin of God - like I said - God's origin is infinite as Infinity and Space - both had no beginning and no end. Always existing.
And both exists for God exist. Of course you're not able to grasp this for your knowledge is only in the physical realm. Your not able to see that which is invisible because you're only looking at the physical and not the spiritual.
But hey that's OK - that's what you believe - and i have no intension of changing it - it's all up to you to do that.
Even though the evidence is not only compelling and convincing but factually accurate.
And since you "don't know the answer" to basic question of life - its origin - then by your own words:
You're faced with just as many questions no matter what your guess is.
I guess you haven't seen many of my posts. I'm not defending neo darwinism, I'm defending modern evolutionary science. The term neo-darwinism was coined in 1895, get with the times. My statement was accurate, albeit simple, but I'm trying to explain to someone who doesn't have a firm grasp on the concept of evolution.
Originally posted by squiz
Originally posted by Barcs
Nope. Genetic changes and environment are the prime "mover of all things" in evolution.
Actually that is not the prevailing paradigm. Neo-Darwinism is a reconcile with mendellion genetics. Put simply it's random mutation at the genetic level sorted through natural selection, the main driver being advantages to survival and reproduction. In regards to the enviroment what we observes is changes in the existing genes, gene plasticity or epigenics. This has often been used falsly (including this thread) as evidence fr neo darwinism. It's fairly well understood in genetics what is happening in these cases, eg.genetic drift and selective breeding. It's just not exactly clear how the genes react so intelligently to the enviroment and so quicky. Dwarfing the effective rate of random mutation.
If you are going to present yourself as an expert you should at least have a little knowledge of what you are defending.
If you are refering to neo-darwinian evolution being based on objective evidence, I'd love to see some, keep in mind the specifics though, random mutation through natural selection. There's only proof of degenerative effects, I can site scientific papers if you wish, actual experiments. Can you show any experiments that empiricly show random mutation can generate new functional gene sequences? let alone new organs and body plans? Experiments conducted by both sides of the issue demonstrate how unlikely it is to occur. E-coli? Fruit Flies? you better look harder. These actually refute neo-darwinism.
I wouldn't consider myself a true 'expert', I'm certainly not an evolutionary biologist just a well informed individual that knows how to learn. Science is more like a hobby. So you agree with evolution, but think its more of a guided process? Sure, it's possible, but I haven't really seen any legit evidence to demonstrate that.
Granted, I believe life evolved and diversified. That seems undeniable to me. What you do not seem to understand is the actual theory of evolution as it stands. Are the mechanism of random mutation enough to do the job?
I'm happy to engage in the science on this issue, but I'll hold you to the same standards and ask for scientific validation. I've lots of questions I'd like to ask of an evolutionary expert such as yourself.
Originally posted by Barcs
I guess you haven't seen many of my posts. I'm not defending neo darwinism, I'm defending modern evolutionary science.
You said random mutation through natural selection. That is incorrect. The mutations happen first, caused by various factors (sun rays, radiation, etc). Natural selection is how certain creatures are better equipped to survive the environment as a result of the mutations.
Now, wild E. coli already has a number of enzymes that normally use citrate and can digest it (it's not some exotic chemical the bacterium has never seen before). However, the wild bacterium lacks an enzyme called a "citrate permease" which can transport citrate from outside the cell through the cell's membrane into its interior. So all the bacterium needed to do to use citrate was to find a way to get it into the cell. The rest of the machinery for its metabolism was already there. As Lenski put it, "The only known barrier to aerobic growth on citrate is its inability to transport citrate under oxic conditions."
By examining the DNA sequence of the E. coli in the neighborhood surrounding the IS [insertion sequence] elements, the investigators saw that several genes involved in central metabolism were knocked out, as well as some cell wall synthesis genes and several others. In subsequent work, Cooper et al. (2001) discovered that twelve of twelve cell lines showed adaptive IS-mediated deletions of their rbs operon, which is involved in making the sugar ribose. Thus, the adaptive mutations that were initially tracked down all involved loss-of-FCT.
I'd love to see some actual experiments.
Beneficial mutations within a bacterial population accumulate during evolution, but performance tends to reach a plateau. Consequently, theoretical evolutionary models need to take into account a “braking effect” in expected benefits on the survival and the reproduction of organisms. This phenomenon (known as negative epistasis) has, for the first time, been demonstrated experimentally by a French-American collaboration, including a team from the Laboratoire Adaptation et Pathogénie des Micro-organismes (CNRS / Université Joseph Fourier). The results are published in Science on 3 June 2011.
Epistatic interactions between mutations play a prominent role in evolutionary theories. Many studies have found that epistasis is widespread, but they have rarely considered beneficial mutations. We analyzed the effects of epistasis on fitness for the first five mutations to fix in an experimental population of Escherichia coli. Epistasis depended on the effects of the combined mutations—the larger the expected benefit, the more negative the epistatic effect. Epistasis thus tended to produce diminishing returns with genotype fitness, although interactions involving one particular mutation had the opposite effect. These data support models in which negative epistasis contributes to declining rates of adaptation over time. Sign epistasis was rare in this genome-wide study, in contrast to its prevalence in an earlier study of mutations in a single gene.
Epistasis has substantial impacts on evolution, in particular, the rate of adaptation. We generated combinations of beneficial mutations that arose in a lineage during rapid adaptation of a bacterium whose growth depended on a newly introduced metabolic pathway. The proportional selective benefit for three of the four loci consistently decreased when they were introduced onto more fit backgrounds. These three alleles all reduced morphological defects caused by expression of the foreign pathway. A simple theoretical model segregating the apparent contribution of individual alleles to benefits and costs effectively predicted the interactions between them. These results provide the first evidence that patterns of epistasis may differ for within- and between-gene interactions during adaptation and that diminishing returns epistasis contributes to the consistent observation of decelerating fitness gains during adaptation.
Four decades ago, several scientists suggested that the impossibility of any evolutionary process sampling anything but a miniscule fraction of the possible protein sequences posed a problem for the evolution of new proteins. This potential problem-the sampling problem-was largely ignored, in part because those who raised it had to rely on guesswork to fill some key gaps in their understanding of proteins. The huge advances since that time call for a careful reassessment of the issue they raised. Focusing specifically on the origin of new protein folds, I argue here that the sampling problem remains. The difficulty stems from the fact that new protein functions, when analyzed at the level of new beneficial phenotypes, typically require multiple new protein folds, which in turn require long stretches of new protein sequence. Two conceivable ways for this not to pose an insurmountable barrier to Darwinian searches exist. One is that protein function might generally be largely indifferent to protein sequence. The other is that relatively simple manipulations of existing genes, such as shuffling of genetic modules, might be able to produce the necessary new folds. I argue that these ideas now stand at odds both with known principles of protein structure and with direct experimental evidence. If this is correct, the sampling problem is here to stay, and we should be looking well outside the Darwinian framework for an adequate explanation of fold origins.
So you agree with evolution, but think its more of a guided process? Sure, it's possible, but I haven't really seen any legit evidence to demonstrate that.
In 2003, Nobel Prize-winning origin-of-life researcher Jack Szostak wrote a review article in Nature lamenting that the problem with "classical information theory" is that it "does not consider the meaning of a message" and instead defines information "as simply that required to specify, store or transmit the string." According to Szostak, "a new measure of information-- functional information--is required" in order to take account of the ability of a given protein sequence to perform a given function.
Information And Entropy – Top-down Or Bottom-up Development In Living Systems?
This paper deals with the fundamental and challenging question of the ultimate origin of genetic information from a thermodynamic perspective. The theory of evolution postulates that random mutations and natural selection can increase genetic information over successive generations. It is often argued from an evolutionary perspective that this does not violate the second law of thermodynamics because it is proposed that the entropy of a non-isolated system could reduce due to energy input from an outside source, especially the sun when considering the earth as a biotic system. By this it is proposed that a particular system can become organised at the expense of an increase in entropy elsewhere. However, whilst this argument works for structures such as snowflakes that are formed by natural forces, it does not work for genetic information because the information system is composed of machinery which requires precise and non-spontaneous raised free energy levels – and crystals like snowflakes have zero free energy as the phase transition occurs. The functional machinery of biological systems such as DNA, RNA and proteins requires that precise, non-spontaneous raised free energies be formed in the molecular bonds which are maintained in a far from equilibrium state. Furthermore, biological structures contain coded instructions which, as is shown in this paper, are not defined by the matter and energy of the molecules carrying this information. Thus, the specified complexity cannot be created by natural forces even in conditions far from equilibrium. The genetic information needed to code for complex structures like proteins actually requires information which organises the natural forces surrounding it and not the other way around – the information is crucially not defined by the material on which it sits. The information system locally requires the free energies of the molecular machinery to be raised in order for the information to be stored. Consequently, the fundamental laws of thermodynamics show that entropy reduction which can occur naturally in non-isolated systems is not a sufficient argument to explain the origin of either biological machinery or genetic information that is inextricably intertwined with it. This paper highlights the distinctive and non-material nature of information and its relationship with matter, energy and natural forces. It is proposed in conclusion that it is the non-material information (transcendent to the matter and energy) that is actually itself constraining the local thermodynamics to be in ordered disequilibrium and with specified raised free energy levels necessary for the molecular and cellular machinery to operate.
Originally posted by squiz
Sorry but that's complete rubbish. No the mutations are random due to errors in the dna mRna to protein transfer.
Natural selection is the mechanism by which beneficial mutations are preserved. Failures will die off. There are other factors, symbiosis, genetic drift and epigenics.
There’s no denying micro evolutionary change. These are simply one or two point mutations. It’s a quantum leap away from the development of new organs and body plans.
Forgive me for not investigating the wall of links at talk origins. All I can say is can you point me to the one that empirically shows new gene sequences emerging and how? We have examples of this in nature because obviously new sequences have emerged. But alas all we have are a few assumptions to give a story of how they may emerge. Just developing a story without demonstrating the steps is not complete science. This is what the majority of cases there entail.
Originally posted by Barcs
Try reading a bit before calling something complete rubbish. :lol
What do you think happens when lots of tiny mutations happen over millions of years? They appear to be BIG changes. You are making the hasty generalization that organisms suddenly grow new organs and redesign. That's not how it works.
Everyone ignores that link. It's getting comical. That wall of links is exactly what shows how they emerge, but again, it's not like they suddenly appear overnight. Small changes happen over time and eventually it becomes big. Sudden environmental changes will accelerate evolution, for example the extinction level event that ended the triassic period paved way for a new type of creature to become dominant. Without it, it's highly unlikely mammals would have ever become as successful as they are today. So you agree with micro evolution, but don't think the small changes ever add up?
Originally posted by squiz
It's still fundamentally Random mutation filtered through natural selection. Random mutations provide the raw genetic material. You said this was wrong?
What do you think happens when lots of tiny mutations happen over millions of years? They appear to be BIG changes. You are making the hasty generalization that organisms suddenly grow new organs and redesign. That's not how it works.
Ah no they don't that's just speculation.
See the research, the evidence says something entirely different. Negative epistasis. There's no evidence that new complex proten folds can manifest from random mutation.
Perhaps it's because there's too many issues there to cover simply. Show me the one that empirically shows exactly how the new genes emerged. Too much to ask?
Darwinism is nothing but filling the gaps with speculation and stories. I'm still waiting for actual evidence of complex protein folds spontaneously forming. Darwin does not even get past this prime objective, the very foundation of life.
Originally posted by vasaga
People should really stop yelling "I want evidence" when they don't hold their own beliefs to the same criteria.
How often must we hear "fossils are rare that's why we lack evidence in such and such"? Evolution can not explain everything without making up excuses that are criticized in other views. Deal with it.
Originally posted by squiz
Onto Lenski’s e-coli experiments. Now this is interesting, I’m using Lenski’s work to support my own argument; after all it’s one of the longest running experiments going and should give us good clues to the efficacy of neo-Darwinism.
It’s been shown that E-coli already had the mechanisms to metabolise citrate.
Now, wild E. coli already has a number of enzymes that normally use citrate and can digest it (it's not some exotic chemical the bacterium has never seen before). However, the wild bacterium lacks an enzyme called a "citrate permease" which can transport citrate from outside the cell through the cell's membrane into its interior. So all the bacterium needed to do to use citrate was to find a way to get it into the cell. The rest of the machinery for its metabolism was already there. As Lenski put it, "The only known barrier to aerobic growth on citrate is its inability to transport citrate under oxic conditions."
Michael Behe has reviewed these experiments quite thoroughly. The ability came about through the knocking out of functions, not additions.
By examining the DNA sequence of the E. coli in the neighborhood surrounding the IS [insertion sequence] elements, the investigators saw that several genes involved in central metabolism were knocked out, as well as some cell wall synthesis genes and several others. In subsequent work, Cooper et al. (2001) discovered that twelve of twelve cell lines showed adaptive IS-mediated deletions of their rbs operon, which is involved in making the sugar ribose. Thus, the adaptive mutations that were initially tracked down all involved loss-of-FCT.
www.lehigh.edu...
The following experiments demonstrate random mutation fails to create new genetic information. Let’s start with Lenski since we are on the subject.
Beneficial mutations within a bacterial population accumulate during evolution, but performance tends to reach a plateau. Consequently, theoretical evolutionary models need to take into account a “braking effect” in expected benefits on the survival and the reproduction of organisms. This phenomenon (known as negative epistasis) has, for the first time, been demonstrated experimentally by a French-American collaboration, including a team from the Laboratoire Adaptation et Pathogénie des Micro-organismes (CNRS / Université Joseph Fourier). The results are published in Science on 3 June 2011.
www2.cnrs.fr...
And finaly from a Thermodynamics point of view. Peer reviewed in a non ID journal. Sorry for posting the abstract in full. But I really like this one.
Originally posted by Barcs
That would actually make sense considering they are not drastically changing the environment where the bacteria live. Either way I don't see how any of this shows evidence of a creator or intelligent designer. It shows that mutations do happen, and that the more beneficial ones survive, which is exactly how evolution works. Were these bacteria given millions of years of observation, with various changes in environment, some drastic? If not, then it can't be reliable enough to simulate complex change. Of course the mutations will level out in a lab simulated environment. Of course there will be genetic loss at some point. Neither is guaranteed, however. There isn't some unspoken law of evolution that every change has to be complex or gain genetic info, species just change over long time periods to adapt to their environment.
And finaly from a Thermodynamics point of view. Peer reviewed in a non ID journal. Sorry for posting the abstract in full. But I really like this one
You are posting things that allegedly conflict with evolution. You AREN'T posting evidence of intelligent design, which is what I requested.
It has often been asserted that the logical entropy of a non-isolated system could reduce, and thereby new information could occur at the expense of increasing entropy elsewhere, and without the involvement of intelligence. In this paper, we have sought to refute this claim on the basis that this is not a sufficient condition to achieve a rise in local order. One always needs a machine in place to make use of an influx of new energy and a new machine inevitably involves the systematic raising of free energies for such machines to work. Intelligence is a pre-requisite.
Ok. Explain the cambrian explosion to me. With evidence, since you said there's so much of it.
Originally posted by Barcs
reply to post by squiz
I'm having a little difficulty understanding that you agree with evolution but not Darwinian evolution, when they are the same thing. Are you a proponent of Lemarkian or another type of evolution?
Originally posted by vasaga
reply to post by Barcs
Ok. Explain the cambrian explosion to me. With evidence, since you said there's so much of it.edit on 10-1-2012 by vasaga because: (no reason given)
Originally posted by squiz
But it's how those bits are arranged. This is where intelligence is needed. A sheet of music conveys information just like the biochemical arrangements. We could look at the genome project like that.
We are seeing the sheet music and not getting the whole picture, what is needed is the musician.