New Study Out Of Sweden Shows Covid Spike Protein From Vaccines Impairs Cell DNA Damage Repair.

This appears to be real science. It is important not to twist this into saying what it does not say, the conclusions are enough to show that the vaccines are probably damaging some immune system adaptive immune functions and also may possibly increase cancer risk. This needs more detailed unbias research to see if it is as bad as it is sounding like in vivo.

It may actually turn out to be worse if it does get into the marrow and organs, but jumping to those conclusions is not science either till they actually do the proper research and interpretation of the research.

I expect that those who have said this vaccine is perfectly safe and effective will try to discredit this research in various ways using Ad Hominum tactics to try to make people believe that it is not relevant.

In vitro and in vivo are two different things, but in this case I am thinking it may cross over, they appear to have taken in consideration these differences, but further research will be necessary in Vivo to verify the association....so we have to make sure that this research continues and is not buried by high ranking health agency leaders who will try to stop this research. Hopefully we do have some politicians who believe in real science to combat these agency heads that backed the implementation of this vaccine technology without proper research.

I think that the FDA, NIH, and CDC in this country will try to blow off this finding because they backed a lie and actually created the lie. According to the video, pfizer never had the time to even test for this, they actually were not required to test for it, the liability of this is on the FDA and CDC and NIH leaders who should have required research on this. Trump trusted the wrong people when he trusted the heads of the agencies, we need to replace those agency heads with people who are looking out for the welfare of the American people, not people trying to make themselves look prestigious and important....and also wealthy.

originally posted by: daskakik
a reply to: Stupidsecrets
The thing is that they are saying the virus is worse than the vax and the virus isn't much of a problem to the majority of people, so why would the vax be?

ETA: Or maybe another way of looking at it is that if the spike protein makes the vax bad you are just as SOL if you got the virus and got over it.

And if the virus isn't much of a problem for the majority of people, why bother with a vax?

Why replace one small risk for another small risk in healthy people?

originally posted by: Itisnowagain
a reply to: new_here
Do current vaccines have full protein spike?

I don't know, but why are you answering my question with a question?
I just want to know if naturally occurring spike protein from infection is causing the same DNA repair issue mentioned in the study.

a reply to: new_here

I think that answer is clearly yes. This study wasn't studying vaccines, but the nCOV itself. The majority of the risks from the vaccine are much greater risks when infected. Blood clots, systemic inflammation, myocarditis, etc.

originally posted by: new_here

originally posted by: Itisnowagain
a reply to: new_here
Do current vaccines have full protein spike?

I don't know, but why are you answering my question with a question?
I just want to know if naturally occurring spike protein from infection is causing the same DNA repair issue mentioned in the study.

From the linked study:

Here, by using an in vitro cell line, we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity

Never mind.

originally posted by: ColeYounger

originally posted by: carewemust

originally posted by: lSkrewloosel
yeah exactly. Government don't want people dropping g like flies anytime soon. 4 to 5 years down the line when enough time has passed people won't put the two and two together.. a reply to: carewemust

Every time I hear, "I got vaccinated 3 months ago, and I'm fine!", I think of Obama's advisor who was recorded 3 times telling staffers to leverage the stupidity of Americans, when pushing their agenda.

It's like when a virologist asked the CDC, Fauci, and Gates how a vaccine was produced so quickly, when it usually takes years. Their collective answer was basically "a bunch of people worked real hard on it."

I think the people who worked real hard on it were people who sold stocks for these companies.

a reply to: Kreeate

So that's a yes? Same issue with virus and vaccine spike protein?

originally posted by: new_here
a reply to: Kreeate

So that's a yes? Same issue with virus and vaccine spike protein?

Maybe? As long as the guys in quality control at the vaccine factory aren’t having an off day? And the vaccine is properly stored for shipping and storage.

a reply to: daskakik

Hmmm

Our findings provide evidence of the spike protein hijacking the DNA damage repair machinery and adaptive immune machinery in vitro. We propose a potential mechanism by which spike proteins may impair adaptive immunity by inhibiting DNA damage repair. Although no evidence has been published that SARS–CoV–2 can infect thymocytes or bone marrow lymphoid cells, our in vitro V(D)J reporter assay shows that the spike protein intensely impeded V(D)J recombination. Consistent with our results, clinical observations also show that the risk of severe illness or death with COVID–19 increases with age, especially older adults who are at the highest risk [22]. This may be because SARS–CoV–2 spike proteins can weaken the DNA repair system of older people and consequently impede V(D)J recombination and adaptive immunity. In contrast, our data provide valuable details on the involvement of spike protein subunits in DNA damage repair, indicating that full–length spike–based vaccines may inhibit the recombination of V(D)J in B cells, which is also consistent with a recent study that a full–length spike–based vaccine induced lower antibody titers compared to the RBD–based vaccine [28]. This suggests that the use of antigenic epitopes of the spike as a SARS–CoV–2 vaccine might be safer and more efficacious than the full–length spike. Taken together, we identified one of the potentially important mechanisms of SARS–CoV–2 suppression of the host adaptive immune machinery. Furthermore, our findings also imply a potential side effect of the full–length spike–based vaccine. This work will improve the understanding of COVID–19 pathogenesis and provide new strategies for designing more efficient and safer vaccines.

originally posted by: new_here
a reply to: Kreeate

So that's a yes? Same issue with virus and vaccine spike protein?

My understanding is that the vaccine does not inhibit DNA damage repair directly, but that the spike protein from Covid can emphasize the potential side effects of the vaccines.

Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.

originally posted by: igloo
And if the virus isn't much of a problem for the majority of people, why bother with a vax?

Why replace one small risk for another small risk in healthy people?

But that swings both ways, in regards to vax fear-mongers.

They are both small risks so why act like humanity is going to be wiped out by the smaller risk?

Has anybody here come across any research as to why some people are able to beat the virus at the bodies first defense, therefore not acquiring the antibodies?

Probably not easy to study this but, it seems the way to go.

a reply to: strongfp
Don't "Hmmm" me bro!

I meant the OP saying the vaxxes are a controlled production and therefore safer than infection with CV is pretty pro-vax.

a reply to: AnInvisibleCorner

There are a few reasons. Severe COVID symptoms result from a delayed Type 1 interferon response. SARSCoV2 can also block these pathways in macrophages and dendritic cells which help to train the adaptive immune cells with viral antigen.

So in an obese patient or a patient with other conditions like cardiac issues or type 2 diabetes, there will be a delay in interferon production in cells infected by the virus. This also rarely happens in healthy people. Interferon blocks virus from reproducing and calls for help through cytokines and inflammatory signaling. You block that and people can get very sick and die once signaling catches up or the innate immune system starts wiping and destroying tissue without signaling for tissue repair etc.

With the no antibody generation, this is a T-cell response that occurs before antibody production even occurs. In these patients, they have cross reactive cytotoxic T-cells. This can target many areas of the virus because they are similar to another virus in some sequence or epitome that they encounter during antigen presentation. So infected cells are destroyed early in infection and a normal interferon response prevents other issues from occurring. There isn’t even a chance for antibody generation.

This doesn’t mean they can’t produce antibodies, they most likely can because of dendritic cell licensing and cross talk but they are not produced because they are not needed.

With the study in this thread and VDJ recombination, you need to be very careful in understanding the major differences that will occur in vitro and in vivo with the editing process to refine antigen targets because there is a significant signal process missing from other components of the immune response that traffic and regulate these cells.

I think in the next few years you will see a shift to alternative antigen targets rather than the spike. And no, people aren’t going to die years from now unless they have something activated like a latent autoantibody receptor hidden hidden or diluted by another receptor. Most issues should happen quickly in these patients that react to the vaccine.

originally posted by: Butterfinger
Thank you for the article.

Sad that huge swathes of populace just accept whatever is mainstreamed at them.

Time to cancel Sweden! About time, they LITERALLY make white people there.

Not any longer, they are now about 1 in 4 ethnic Asian Islamic (and other nationality's including Somali etc) and being outbred by migrants that have settled there since Sweden originally opened it's borders, the result is that within one and a half to maybe two and a half generations Sweden will have a majority of NON Nordic resident's.

Native (As in the famous Blond, Blue Eyed Swedes - a stereotype many are brown eyed and brunette though Blond is VERY common among the NATIVE population) Swedes birth rate is LESS than parity meaning they have a falling birth rate and already only had about eight million swedes while the Migrant Swedes (since they have passports that say they are Swedish having been given citizenship) are having more than three times as many children on average as the INDIGINOUS Swedes.

Anyway what's wrong with a Parsnip.

Everyone with even half a brain knew there was something fishy about the Vaccine, The Pharmaceutical Corporations refusing to go along and release it unless they were given some kind of immunity from prosecution was a BIG - very BIG - red light and warning sign.

Athletes dropping dead around the world after having the shot or the booster was ANOTHER - BIG - Red Warning light.

I mean blood clotting that can be lethal, cause strokes, damage the heart and then there is the possibility that the Spike Protein may bind to the Placenta in pregnant woman and possibly make conception more difficult in not already pregnant woman.

Now we know from this study that it damages part of the DNA by hindering it's replication and eventually even potentially splitting it in two at two locations, one linked to Cancer and the other as yet of unknown importance to the human organism.

Then we have leaked videos in which people are blaming NOT the Messenger RNA component of the Vaccine but the matrix in which it is delivered - fluid that has dodgy chemicals and all manner of junk and crap in it for causing damage to people.

Yes I don't want to drop dead from the virus but I also don't want to be some Frankenstein's guinea pig OR go and jump of a cliff just to keep the global elitists whom want to cull the rest of us now they have 3d printing technology and more and more advanced robotics to replace the now redundant workforce happy.

Though I might just to get away from all the depression I suffer, I mean that cliff looks' pretty inviting these day's, leave a note saying "Lock this down you suckers - and I hope your mop breaks haha".

Thank you for the thorough reply, I can't say I fully understand it but: you are basically telling me I've been growing my noise hair out for nothing!

Only joking, thank you again... Sorry about the humour

a reply to: TheAMEDDDoc

a reply to: daskakik

I just quoted right from ops link showing that the article concludes exactly that... buddy.

a reply to: AnInvisibleCorner

Yeah no worries, articles like this are interesting because they show how viruses can adapt to suppress our immune responses, in this case it seems to be adaptive responses with the B-Cell receptor editing and processing that leads to antibody generation. T cell receptors could be influenced as well. VDJ recombination is one of the more challenging aspects of immunology but it is an interesting one.

In these cases in vivo is usually different than in vitro because of additional signaling but it gives us a baseline to work from in overcoming these issues and generating vaccine and medication targets that we can train the body to hit or target before this is even an issue.

Influenza and other viruses can do this as well and similar functions, it’s just what they do.