Corona Virus Updates Part 6

a reply to: CrazeeWorld777

Well they are not exactly kept as cute cuddly pets with long and happy fulfilled lives. They are farmed for their fur, which includes the skin on which it grows.

a reply to: MonkeyBalls2

This gets into codons again so they can produce more proteins from their limited genetic material. Many viruses do it with alternative start sites in the gene or another method called ires which is one way they can hijack host protein production once those viral genes start showing up.

Our cells do it too when they’re in trouble to tell the immune system to destroy the cell or to present antigen (antibody generating proteins), cancers use it to overcome nutrient deficiencies and initiate abnormal protein production through something called cap independent pathways so they out compete healthy cells, it’s like an improvised construction site, sort of, cap independent means the protein construction complex is at an abnormal site compared to normal protein expression.

Those nucleotides and codons are read in groups of three to make an amino acid from that sequence. If you move that reading frame up one or down one or two spaces, you can completely change the sequence of amino acids and produce different proteins from the same genes. Genes usually start translation from a specific site from a specific complex to translate the genetic code to a protein.

A little more detail, not necessary but helpful:

The protein factories bind to an enzyme and something called transfer RNA and latch onto the genetic transcript and they only attach amino acids that correspond to that specific sequence. A common start codon is AUG, initiated by something called met-transfer-RNA that can read the start site. Each transfer RNA - enzyme complex recognizes only its corresponding code so amino acids don’t get mixed up. it searches for that site and then starts reading the gene at only that site and builds the protein. Like having a specialist responsible for each phase of construction, only they know how to do that specific site.

We look for markers that help us identify these start sites and can predict what proteins will be made. If viruses after this and start the process somewhere else, it’s much harder to predict the protein that will be made and develop methods to target it.

It’s like hiding a blueprint in a blueprint, because you don’t have the space to store it and can only fit one sheet of paper inside an envelope. It gets crazy, but helpful to understand if you’re curious.

a reply to: TheAMEDDDoc

I'm going to have to read this again tomorrow with more rested eyes lol
(Midnight here now).

Will also have to do some basic reasearch on some of the simple Biology involved.
I haven't done Biology since my High School days

I have to admit, its a bit of a *whoosh* over my head right now, lol.

Numbers Update for Europe, and Elsewhere (No BNO) :






New Deaths :



New Cases :



www.worldometers.info...

a reply to: MonkeyBalls2

Sorry, it’s kind of like learning a new language, it gets crazy and there are so many moving parts you wonder how some of these mechanisms, many of which are based on random collisions, occur in the first place. It’s nuts. I would probably be in the same boat with programming lol. I do want to learn some basics for informatics and databases though at some point.

When I first looked at this stuff and some of my initial graduate courses, I thought, there’s no way, it’s not humanly possible to learn this and then be expected to remember it on a test. Chemistry was the same way, I thought those professors were monsters....ugh. It eventually starts to come together.

It’s cool how it works though.

Numbers Update for Europe, and ELsewhere (No BNO) :






New Deaths :



New Cases :



www.worldometers.info...

a reply to: TheAMEDDDoc

Talking of learning a new language, imagine having to learn to do 16bit binary equations in the very late 1990's.
It was never ever going to be useful, and was a right pain in the backside to do, but that is what was taught.
Intel i960 I hate you (A printer processor as they told us, of all things useful!)

Databases on the other hand are very very useful.
I learned from Dr Babis Theodoulidis at UMIST, when it was still called that.
He had a great lecture on MetaData.
(There was probably more than one.)

I'm on Hols next week repairing cars, and i'll be able to do some limited reading.
Seems a good subject to be knowledgable about at the moment (The Spike Protein and Stuff, I already know about cars)...

originally posted by: MonkeyBalls2
a reply to: TheAMEDDDoc

I'm going to have to read this again tomorrow with more rested eyes lol

(Midnight here now).

Will also have to do some basic reasearch on some of the simple Biology involved.
I haven't done Biology since my High School days

I have to admit, its a bit of a *whoosh* over my head right now, lol.

The last 3 pages just *wooshed* over my head lol

originally posted by: Psychoparrot
a reply to: CrazeeWorld777

Well they are not exactly kept as cute cuddly pets with long and happy fulfilled lives. They are farmed for their fur, which includes the skin on which it grows.

Yes, its cruel either way you look at it.

Taking a couple days off posting, back tomorrow.

a reply to: MonkeyBalls2

We all need time out. Your daily postings are appreciated and I hope ypu are OK.
Rainbows
Jane

Well, well, well....a damning report, including allegations of corruption of the Government and SAGE's response to COVID19 by the BMJ (British Medical Journal) no less, here in the UK
Well worth the 5 minute read....

Science is being suppressed for political and financial gain. Covid-19 has unleashed state corruption on a grand scale, and it is harmful to public health.1 Politicians and industry are responsible for this opportunistic embezzlement. So too are scientists and health experts. The pandemic has revealed how the medical-political complex can be manipulated in an emergency—a time when it is even more important to safeguard science.

When science is supressed by the political-medical complex, people die

Rainbows
Jane

a reply to: angelchemuel

Thank's so much for posting that - definitely worth reading!

And some good information sourced in the footnotes as well!

a reply to: lostgirl

It did make me have a random thought that connected to Dominic Cummings and he knows this and agrees with BMJ (remember Durham/Barnard Castle?) and that's why he has gone for not 'towing the party line' regarding current lockdown. Which is why Boris was trying the tiered approach (Cummings, he is an analyst after all regardless of what our personal feelings are about him) and was against a full lockdown.....like I said, just a rambling thought.

Rainbows
Jane
ETA If I remember correctly, Cummings sat on the board that ran a 'mock pandemic' and he concluded our NHS was in no position or equipped to deal with one. and his recommendation was that more money needed to be spent to make sure we were. That 'mock up' was run about 18 months before first lockdown.

Numbers Update for Europe, and Elsewhere (No BNO) :






New Deaths :



New Cases :



www.worldometers.info...

a reply to: angelchemuel

There was "Exercise Cygnus" in 2016 ?
Don't see his name mentioned in this Telegraph Article

I think there was one done later, in 2019 iirc..

edit It was "Event 201" Pandemic preparedness exercise.

Youtube "Event 201" link from CenterforHealthSecurity is the one from last year.

a reply to: MonkeyBalls2

Thank you....but weren't you taking a couple of days off

Rainbows
Jane

a reply to: angelchemuel

Personally I think Cummings leaving just after Trump loses is not a coincidence. I think Boris and Cummings bet the farm on Trump winning and giving the U.K. a favourable trade Deal post hard Brexit. Now that Biden putting a deal in doubt Boris is quickly back stepping with the EU desperate for a last minute rescue deal (Barnier made is sudden and unexpected visit last week).

Cummings will be fuming at the concessions Boris is now willing to make and wants no part of it. Nor will Boris want him around threatening to scupper Boris blended knee renegotiations.

a reply to: McGinty

That is another very possible scenario as well. Boris is well known for not being able to make his mind up and sticking to it. Cummings on the other hand is very analytical and calculating and will stick to his guns and probably doesn't 'suffer fools gladly'. I don't know if it has been said anywhere and it's purely my speculation, but I feel Cummings is on the spectrum. He is much more the Churchill or Thatcher than Boris will ever be. I think Boris' days are numbered.

Speculating again, wasn't Cummings connected to Cambridge Analytica? So random thought again with the US election. What if the claimed ballot shenanigans are proven with Dominion and Cummings new there would be and warned Boris but was ignored? Again it is only something I have read somewhere and is yet to be proven, but the machines were connected to the internet and 5 countries were named, the UK being one of them. Again purely speculation on my part because of Cummings gift with analysing statistics and 'reading' people.

I also understand that Carrie (wife to be) has had a lot to say about Cummings and played a part in his departure.

Him leaving via the front door, his demeanour and gait made it very clear he is fuming and we wont have heard the last of him.

Rainbows
Jane

Numbers Update for Europe, and Elsewhere (No BNO) :






New Deaths :



New Cases :



www.worldometers.info...-top

Fell asleep two nights in a row, lol.