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"Locomotion is important for a number of activities such as mating and searching for food. It turns out that gut bacteria may be critical for fundamental behaviors in animals," said Dr. Mazmanian.
Fruit flies carry between five and 20 different species of bacteria and Dr. Mazmanian's team treated the germ-free animals with individual strains of those microbes. When the flies received Lactobacillus brevis, their movements slowed down to normal speed. L. brevis was one of only two species of bacteria that restored normal behavior in the germ-free flies.
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"Gut bacteria may play a similar role in mammalian locomotion, and even in movement disorders such as Parkinson's disease," said Dr. Mazmanian.