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originally posted by: ElectricUniverse
Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002.
Gallagher CM1, Goodman MS.
www.ncbi.nlm.nih.gov...,+NHIS+1997-2002
Autoimmunity. 2005 May;38(3):235-45.
Infection, vaccines and other environmental triggers of autoimmunity.
Molina V1, Shoenfeld Y.
www.ncbi.nlm.nih.gov...
J Toxicol Environ Health A. 2011;74(14):903-16. doi: 10.1080/15287394.2011.573736.
A positive association found between autism prevalence and childhood vaccination uptake across the U.S. population.
www.ncbi.nlm.nih.gov...
originally posted by: ElectricUniverse
Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunction
Maryline Couettea, c, Marie-Françoise Boissea, c, Patrick Maisona, d, 2, Pierre Brugierese, Pierre Cesaroa, c,
Xavier Chevalierf, Romain K. Gherardib, g, h, Anne-Catherine Bachoud-Levia, c, 1, François-Jérôme Authierb, g, h, 1,
www.sciencedirect.com...
The research abstract I excerpt below is a follow up on the above research.
Long-term follow-up of cognitive dysfunction in patients with aluminum hydroxide-induced macrophagic myofasciitis (MMF) ☆
Elodie Passeria, b, Chiara Villac, Maryline Couetteb, d, Emmanuel Ittie, Pierre Brugieresf, Pierre Cesarob, e, Romain K. Gherardia, g, h, Anne-Catherine Bachoud-Levib, d, François-Jérôme Authiera, g, h
DOI: 10.1016/j.jinorgbio.2011.08.006
www.sciencedirect.com...
Immunol Res. 2013 Jul;56(2-3):304-16. doi: 10.1007/s12026-013-8403-1.
Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity.
Shaw CA1, Tomljenovic L.
www.ncbi.nlm.nih.gov...
Another study on mercury toxicity.
A Case-Control Study of Mercury Burden in Children with Autistic Spectrum Disorders
J Toxicol Environ Health A. 2007 May 15;70(10):837-51.
A case series of children with apparent mercury toxic encephalopathies manifesting with clinical symptoms of regressive autistic disorders.
Geier DA1, Geier MR.
Author information
Abstract
Impairments in social relatedness and communication, repetitive behaviors, and stereotypic abnormal movement patterns characterize autism spectrum disorders (ASDs). It is clear that while genetic factors are important to the pathogenesis of ASDs, mercury exposure can induce immune, sensory, neurological, motor, and behavioral dysfunctions similar to traits defining or associated with ASDs. The Institutional Review Board of the Institute for Chronic Illnesses (Office for Human Research Protections, U.S. Department of Health and Human Services, IRB number IRB00005375) approved the present study. A case series of nine patients who presented to the Genetic Centers of America for a genetic/developmental evaluation are discussed. Eight of nine patients (one patient was found to have an ASD due to Rett's syndrome) (a) had regressive ASDs; (b) had elevated levels of androgens; (c) excreted significant amounts of mercury post chelation challenge; (d) had biochemical evidence of decreased function in their glutathione pathways; (e) had no known significant mercury exposure except from Thimerosal-containing vaccines/Rho(D)-immune globulin preparations; and (f) had alternate causes for their regressive ASDs ruled out. There was a significant dose-response relationship between the severity of the regressive ASDs observed and the total mercury dose children received from Thimerosal-containing vaccines/Rho (D)-immune globulin preparations. Based upon differential diagnoses, 8 of 9 patients examined were exposed to significant mercury from Thimerosal-containing biologic/vaccine preparations during their fetal/infant developmental periods, and subsequently, between 12 and 24 mo of age, these previously normally developing children suffered mercury toxic encephalopathies that manifested with clinical symptoms consistent with regressive ASDs. Evidence for mercury intoxication should be considered in the differential diagnosis as contributing to some regressive ASDs.
...
www.ncbi.nlm.nih.gov...
I could keep posting study after study, but to some people for whatever reason it won't matter how many of these studies are shown. These people will just continue to dismiss all this evidence.
Here's the response to the first two about MMF.
www.who.int...
Basically what that says is since there were no control groups it's impossible to rule a specific association.
It's just correlation.
The third from Shaw cites ASIA syndrome.
ASIA syndrome is a fabricated syndrome invented by the notable anti-vaxxer Schoenfeld and is in fact not a syndrome but an artefact found in analysis. And an artefact only found by one group of researchers, Schoenfeld's...
Disingenuous much?
And then you post a paper from the Geiers...
A pair who will do anything to prove a link to autism and mercury because they run a business lying to parents that they can CURE their children's autism by removing the non-existent mercury from them.
They use Lupron.
Lupron is a chemical used for chemical castration.
There is no scientific evidence that it chelates mercury nor that it cures autism.
A little piece showing just how honest and ethical the Geiers are
leftbrainrightbrain.co.uk...
Will you take any notice of these rebuttals?
No, I don't think you will.
You WANT to believe that vaccines are harmful and will post anything to try to confirm that belief.
originally posted by: ElectricUniverse
originally posted by: babybunnies
It's not a Constitutional right to refuse a flu shot. It's part of their employment contract, that she voluntarily signed, of her own accord, without pressure.
...
It is if you are being forced to inject a vaccine that has substances which several research studies have found can cause autism and other neurological disorders on children and even on some adults. The hospital should have offered her a vaccine which did not contain aluminum adjuvants, or ethyl mercury.
Then again, how can we be sure that even vaccines which supposedly are "mercury free" or aluminum free through the claimed "purification process" that manufacturers state they have done when the CDC and the FDA are not making sure these purification processes work as intended? In fact neither the CDC or FDA know for certain that these purification processes have been done since they make no tests to prove that it has been done.
Remember that there have been many vaccines which were approved by the FDA and the CDC, yet they were contaminated with other viruses and bacteria and have been given to millions of people and children. This has happened despite the claim that the FDA tests all batches of vaccines before they are approved and distributed.
There is also the fact that some vaccine manufacturers, either by error or done on purpose to save money have mislabeled some vaccines. There have been some cases in which even some scientists working for the FDA or the CDC have come forward as whistleblowers telling us that the FDA and the CDC have on purpose hidden facts about vaccines which show many of them not to be safe. These whistleblowers are biochemists who have worked on vaccine research for the CDC and FDA and they are not just your typical office employee.
originally posted by: Pardon?
Here's the response to the first two about MMF.
www.who.int...
Basically what that says is since there were no control groups it's impossible to rule a specific association.
It's just correlation.
originally posted by: Pardon?
The third from Shaw cites ASIA syndrome.
ASIA syndrome is a fabricated syndrome invented by the notable anti-vaxxer Schoenfeld and is in fact not a syndrome but an artefact found in analysis. And an artefact only found by one group of researchers, Schoenfeld's...
Disingenuous much?
originally posted by: Pardon?
And then you post a paper from the Geiers...
A pair who will do anything to prove a link to autism and mercury because they run a business lying to parents that they can CURE their children's autism by removing the non-existent mercury from them.
They use Lupron.
Lupron is a chemical used for chemical castration.
There is no scientific evidence that it chelates mercury nor that it cures autism.
A little piece showing just how honest and ethical the Geiers are
leftbrainrightbrain.co.uk...
Expert Opin Investig Drugs. 2007 Nov;16(11):1851-63.
Leuprolide acetate: a drug of diverse clinical applications.
Wilson AC1, Meethal SV, Bowen RL, Atwood CS.
Author information
Abstract
Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. As its basic mechanism of action, leuprolide acetate suppresses gonadotrope secretion of luteinizing hormone and follicle-stimulating hormone that subsequently suppresses gonadal sex steroid production. In addition, leuprolide acetate is presently being tested for the treatment of Alzheimer's disease, polycystic ovary syndrome, functional bowel disease, short stature, premenstrual syndrome and even as an alternative for contraception. Mounting evidence suggests that GnRH agonist suppression of serum gonadotropins may also be important in many of the clinical applications described above. Moreover, the presence of GnRHR in a multitude of non-reproductive tissues including the recent discovery of GnRHR expression in the hippocampi and cortex of the human brain indicates that GnRH analogs such as leuprolide acetate may also act directly via tissue GnRHRs to modulate (brain) function. Thus, the molecular mechanisms underlying the therapeutic effect of GnRH analogs in the treatment of these diseases may be more complex than originally thought. These observations also suggest that the potential uses of GnRH analogs in the modulation of GnRH signaling and treatment of disease has yet to be fully realized.
...
...
LUPRON DEPOT‑PED® (leuprolide acetate for depot suspension) 7.5 mg, 11.25 mg and 15 mg for 1-month and 11.25 mg and 30 mg for 3-month administration are prescribed for the treatment of children with central precocious puberty (CPP).
Doctors may diagnose children with CPP when signs of sexual maturity begin to develop in girls under the age of 8 or boys under the age of 9. Your doctor should perform tests to rule out possible causes of early puberty that would require different treatment (e.g., tumors).
...
originally posted by: Pardon?
Will you take any notice of these rebuttals?
No, I don't think you will.
You WANT to believe that vaccines are harmful and will post anything to try to confirm that belief.
DNA released from dying host cells mediates aluminum adjuvant activity
Thomas Marichal,
Keiichi Ohata,
Denis Bedoret,
Claire Mesnil,
Catherine Sabatel,
Kouji Kobiyama,
Pierre Lekeux,
Cevayir Coban,
Shizuo Akira,
Ken J Ishii,
Fabrice Bureau
& Christophe J Desmet
Affiliations
Contributions
Corresponding authors
Nature Medicine 17, 996–1002 (2011) doi:10.1038/nm.2403 Received 11 February 2011 Accepted 19 May 2011 Published online 17 July 2011
Abstract
Abstract•
References•
Author information•
Supplementary information
Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination, although their mechanisms of action are poorly understood. Here we report that, in mice, alum causes cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal mediating alum adjuvant activity. Furthermore, we propose that host DNA signaling differentially regulates IgE and IgG1 production after alum-adjuvanted immunization. We suggest that, on the one hand, host DNA induces primary B cell responses, including IgG1 production, through interferon response factor 3 (Irf3)-independent mechanisms. On the other hand, we suggest that host DNA also stimulates 'canonical' T helper type 2 (TH2) responses, associated with IgE isotype switching and peripheral effector responses, through Irf3-dependent mechanisms. The finding that host DNA released from dying cells acts as a damage-associated molecular pattern that mediates alum adjuvant activity may increase our understanding of the mechanisms of action of current vaccines and help in the design of new adjuvants.
...
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses.
...
IgE not only provides protective immunity against helminth parasites but can also mediate the type I hypersensitivity reactions that contribute to the pathogenesis of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.
...
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
Christopher Exley, Louise Swarbrick, Rhomain K. Gherardi, Francois-Jérôme Authier
Received: August 28, 2008; Accepted: September 4, 2008; Published Online: November 12, 2008
DOI: dx.doi.org...
Summary
Macrophagic myofasciitis and chronic fatigue syndrome are severely disabling conditions which may be caused by adverse reactions to aluminium-containing adjuvants in vaccines. While a little is known of disease aetiology both conditions are characterised by an aberrant immune response, have a number of prominent symptoms in common and are coincident in many individuals. Herein, we have described a case of vaccine-associated chronic fatigue syndrome and macrophagic myofasciitis in an individual demonstrating aluminium overload. This is the first report linking the latter with either of these two conditions and the possibility is considered that the coincident aluminium overload contributed significantly to the severity of these conditions in this individual. This case has highlighted potential dangers associated with aluminium-containing adjuvants and we have elucidated a possible mechanism whereby vaccination involving aluminium-containing adjuvants could trigger the cascade of immunological events which are associated with autoimmune conditions including chronic fatigue syndrome and macrophagic myofasciitis.
...
Aluminium, carbonyls and cytokines in human nipple aspirate fluids: Possible relationship between inflammation, oxidative stress and breast cancer microenvironment
F. Mannello, , D. Ligi, M. Canale
Department of Biomolecular Sciences, Section of Clinical Biochemistry and Cell Biology, University ‘Carlo Bo’ of Urbino, Italy
Received 2 May 2013, Revised 2 July 2013, Accepted 5 July 2013, Available online 12 July 2013
Abstract
The human breast is likely exposed to Al (aluminium) from many sources including diet and personal care products. Underarm applications of aluminium salt-based antiperspirant provide a possible long-term source of exposure, especially after underarm applications to shaved and abraded skin. Al research in breast fluids likely reflects the intraductal microenvironment. We found increased levels of aluminium in noninvasively collected nipple aspirate fluids (NAF) from 19 breast cancer patients compared with 16 healthy control subjects ( 268 vs 131 μg/l, respectively ; p < 0.0001 ). In the same NAF samples we found significantly increased levels of protein oxidative carbonyls in cancer patients compared to healthy women ( 2.35 vs 0.41 nmol/mg prot, respectively ; p < 0.0001 ). Aluminium content and carbonyl levels showed a significant positive linear correlation (r2 0.6628, p < 0.0001). In cancer NAF samples (containing higher amounts of aluminium salts) we also found a significantly increased levels of pro-inflammatory cytokines (IL-1β, IL-6, IL-12 p70, and TNF-α) and chemoattractant CC and CXC chemokines (IL-8, MIP-1α and MCP-1). In 12 invasive cancer NAF samples we found a significant positive linear correlation among aluminium, carbonyls and pro-inflammatory IL-6 cytokine (Y = 64.79x − 39.63, r2 0.8192, p < 0.0005), as well as pro-inflammatory monocyte chemoattractant MCP-1 cytokine (Y = 2026x − 866, r2 0.9495, p < 0.0001). In addition to emerging evidence, our results support the possible involvement of aluminium ions in oxidative and inflammatory status perturbations of breast cancer microenvironment, suggesting aluminium accumulation in breast microenvironment as a possible risk factor for oxidative/inflammatory phenotype of breast cells.
...
Plasma aluminum is a risk factor for oxidative stress and inflammation status in hemodialysis patients
Chih-Hung Guo, Chia-Liang Wang
Institute of Biomedical Nutrition, Hung Kuang University, Taichung 433, Taiwan, ROC
Department of Nephrology, Kuang-Tien General Hospital, Taichung 433, Taiwan, ROC
Received 9 February 2011, Revised 11 August 2011, Accepted 14 August 2011, Available online 25 August 2011
DOI: 10.1016/j.clinbiochem.2011.08.1132
Abstract
Objectives
The association between aluminum (Al), essential trace metals, oxidative stress, and inflammation status was evaluated in hemodialysis patients.
Design and methods
Biochemical parameters in blood were determined in long-term hemodialysis patients (n = 69) and age- and sex-matched healthy individuals (n = 30).
Results
Compared with healthy subjects, patients had significantly higher concentrations of plasma Al. Elevated Al was negatively associated with the essential metals zinc, selenium, and iron. Al concentrations were strongly and positively correlated with contents of the oxidation products malondialdehyde and protein carbonyl. Inverse relationships were observed between Al concentrations and reduced concentrations of glutathione, β-carotene, vitamin C, and vitamin E. Patients were also observed to have significantly increased production values of plasma high-sensitivity C-reactive protein, tumor necrosis factor-α, and interleukin-5.
Conclusion
An increased plasma Al concentration is associated with disturbed concentrations of essential metals, increased oxidative stress, and increased inflammation status in hemodialysis patients
...
Hippocampal neuronal metal ion imbalance related oxidative stress in a rat model of chronic aluminum exposure and neuroprotection of meloxicam
Lijuan Yu1, Rong Jiang2, Qiang Su1, Huarong Yu1* and Junqing Yang1*
* Corresponding authors: Huarong Yu [email protected] - Junqing Yang [email protected]
Author Affiliations
1 Department of Pharmacology, Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Medical College Rd. No 1, Chongqing Medical University, Chongqing 400016, P. R. China
2 Department of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing 400016, P. R. China
For all author emails, please log on.
Behavioral and Brain Functions 2014, 10:6 doi:10.1186/1744-9081-10-6
The electronic version of this article is the complete one and can be found online at: www.behavioralandbrainfunctions.com...
Received: 2 September 2013
Accepted: 28 February 2014
Published: 11 March 2014
© 2014 Yu et al.; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (creativecommons.org...), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
Abstract
Neurodegenerative diseases remain a significant unresolved societal burden afflicting millions of people worldwide. Neurons in the brain are highly sensitive to oxidative stress, which can be induced by metal toxicity. In this paper, a chronic aluminum overload-induced model of neurodegeneration was used to investigate whether metal ions (Al, Fe, Mn, Cu and Zn)-related oxidative stress was involved in neurodegenerative mechanism and to identify the protective action of meloxicam against rat hippocampal neuronal injury. The metal ion contents, activity of superoxide dismutase (SOD), and content of malondialdehyde (MDA) were detected. The results showed that the spatial learning and memory (SLM) function was significantly impaired in chronic aluminum overload rats. Considerable karyopycnosis was observed in hippocampal neurons. The SOD activity was weakened and the MDA content increased both significantly. In the hippocampus, Al, Fe, Mn, Cu, and Zn contents increased by 184.1%, 186.1%, 884.2%, 199.4% and 149.2%, respectively. Meloxicam administration (without Al) had no effect compared with the control group, while meloxicam treatment with aluminum exposure significantly protected rats from SLM function impairment, neuron death, lower SOD activity, higher MDA content and brain metal ion imbalance. Our findings suggest that the cerebral metal ion imbalance-related oxidative stress is involved in mechanism of cerebral injury and neurodegeneration induced by chronic Al overload in rats, and that meloxicam protects neurons by reducing metal ion imbalance-related oxidative stress.
Keywords: Neurodegeneration; Metal ion; Meloxicam; Aluminum overload; Oxidative stress
...
originally posted by: ElectricUniverse
originally posted by: Pardon?
Here's the response to the first two about MMF.
www.who.int...
Basically what that says is since there were no control groups it's impossible to rule a specific association.
It's just correlation.
First of all, note the above. This is how you "properly" quote someone and then post your response outside the quote. The way you quote someone in your threads is very confusing. Not to mention that you also leave out links to where much of your info comes from.
Second, you actually think people are stupid. You post a link to a WHO document which mentions a study from 2002 in response to a study from 2011?... So, you want to claim the earlier statement from the WHO link you gave about a study from 2002 refutes studies done AFTER 2002, including the one I posted from 2011?...
You would try anything and everything to dismiss this won't you?... From LYING by claiming "vaccines don't contain ethylmercury/mercury anymore", to twisting what people actually say and posting "opinions" from blogs, to using nothing but insults to try to dismiss what you actually can't refute using a rational argument...
originally posted by: ElectricUniverse
Yeah...talk about "disingenuous"... Dismissing what a physician and autoimmunity researcher has to say about adjuvants in vaccines just by trying to insult him and dismiss whatever he, alongside many other doctors, and specialists have to say which contradict "Pardon's" claims.... Ironic that you mention this to say the least...
Let's continue...
originally posted by: Pardon?
And then you post a paper from the Geiers...
A pair who will do anything to prove a link to autism and mercury because they run a business lying to parents that they can CURE their children's autism by removing the non-existent mercury from them.
They use Lupron.
Lupron is a chemical used for chemical castration.
There is no scientific evidence that it chelates mercury nor that it cures autism.
A little piece showing just how honest and ethical the Geiers are
leftbrainrightbrain.co.uk...
originally posted by: ElectricUniverse
Wow... First, to make it clear I don't endorse using Lupron in children to chelate because it has a lot of negative side effects, and castration isn't one of them... But, to the point, you are being completely dishonest on why leuprolide acetate/Lupron is used for, and the different effects it may have depending on what doses and with what frequency it is used...
Let's actually read what real medical science has to say about Lupron/leuprolide acetate shall we?...
Expert Opin Investig Drugs. 2007 Nov;16(11):1851-63.
Leuprolide acetate: a drug of diverse clinical applications.
Wilson AC1, Meethal SV, Bowen RL, Atwood CS.
Author information
Abstract
Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. As its basic mechanism of action, leuprolide acetate suppresses gonadotrope secretion of luteinizing hormone and follicle-stimulating hormone that subsequently suppresses gonadal sex steroid production. In addition, leuprolide acetate is presently being tested for the treatment of Alzheimer's disease, polycystic ovary syndrome, functional bowel disease, short stature, premenstrual syndrome and even as an alternative for contraception. Mounting evidence suggests that GnRH agonist suppression of serum gonadotropins may also be important in many of the clinical applications described above. Moreover, the presence of GnRHR in a multitude of non-reproductive tissues including the recent discovery of GnRHR expression in the hippocampi and cortex of the human brain indicates that GnRH analogs such as leuprolide acetate may also act directly via tissue GnRHRs to modulate (brain) function. Thus, the molecular mechanisms underlying the therapeutic effect of GnRH analogs in the treatment of these diseases may be more complex than originally thought. These observations also suggest that the potential uses of GnRH analogs in the modulation of GnRH signaling and treatment of disease has yet to be fully realized.
...
www.ncbi.nlm.nih.gov...
In order to be "castrated chemically" by a drug such as leuprolide acetate you need that person to continuously use the drug. If use of the drug is discontinued, and depending on what frequency and how long it was used, "chemical castration" is generally reversible... But of course you can't state any of that instead you make a bold statement that "Lupron causes chemical castration" relying on the fact that most people won't even bother to look at what this drug is used for and what can, or can't do.
Lupron isn't used to mainly "chemically castrate people"... Most of it's used is not to "chemically castrate" but it is used to treat the symptoms of certain types of cancer by slowing down the production of hormones.
BTW, Lupron is also used to treat children with central precocious puberty among other uses.
...
LUPRON DEPOT‑PED® (leuprolide acetate for depot suspension) 7.5 mg, 11.25 mg and 15 mg for 1-month and 11.25 mg and 30 mg for 3-month administration are prescribed for the treatment of children with central precocious puberty (CPP).
Doctors may diagnose children with CPP when signs of sexual maturity begin to develop in girls under the age of 8 or boys under the age of 9. Your doctor should perform tests to rule out possible causes of early puberty that would require different treatment (e.g., tumors).
...
www.lupron.com...
Of course, instead of actually informing people of what this drug is used for you resort to exaggerating what it does by implying that "leurolide acetate/Lupron castrates chemically"... But of course someone like you would "believe" the above more so when you have even tried to imply that it doesn't matter at what doses children or adults get aluminum, or mercury into their bodies. You seem to 'believe" that "the body will excrete it all "miracously" no matter what dose of mercury or aluminum is introduced into a person's body...
originally posted by: ElectricUniverse
But of course someone like you would "believe" the above more so when you have even tried to imply that it doesn't matter at what doses children or adults get aluminum, or mercury into their bodies. You seem to 'believe" that "the body will excrete it all "miracously" no matter what dose of mercury or aluminum is introduced into a person's body...
originally posted by: ElectricUniverse
a reply to: Pardon?
First of all, and like I have already mentioned, you need to learn to post links to all the excerpts you give, and properly quote the sources you are giving from external links. As in using within quotes [ ex ] when you start to quote from an external link, and [ /ex ] when you finish quoting. It's hard to properly discern when you are excerpting quotes from an external link or when you are making a comment in response to what another member has written. Not to mention that you keep giving "opinions" from blogs as evidence...
As to the claims by this "Prometheus" person you are quoting, there have been studies and even a whistleblower, among others, of a vaccine manufacturer who would "disagree", at least when he was being recorded and didn't know it, with your claims and those of "Prometheus" about no evidence that the prevalence of autism is higher in some races than in others.
As to the research on HBV and the incidence of autism in neonatal children. First, even in the paper the researchers specified the differences in the age among the children in the study who were vaccinated (before 1999) and the non-vaccinated group.
The researchers were trying to find if there was a similar link of autism in other age groups of vaccinated children, because in case you didn't know among the groups which are recommended that should be vaccinated for HBV, it includes children/young adults who haven't received the vaccine before age of 19.
Of course, any sane person would also know that aluminum and other compounds/substances such as ethylmercury would affect neonatal, and generally young children more than it would affect older patients, but I am guessing "Prometheus" and "Pardon" didn't take this into account either.
BTW, do notice that I specifically mentioned "among other groups" that are recommended to be vaccinated for HBV. I state this because I know damn well you will try to twist anything I type around in your attempts to dismiss what I have to say or post as evidence here.
Anyways, here is more evidence of the "non-existant link claimed by Pardon et al" of aluminum adjuvants and ethylmercury with neurological disorders and other health problems...
DNA released from dying host cells mediates aluminum adjuvant activity
Thomas Marichal,
Keiichi Ohata,
Denis Bedoret,
Claire Mesnil,
Catherine Sabatel,
Kouji Kobiyama,
Pierre Lekeux,
Cevayir Coban,
Shizuo Akira,
Ken J Ishii,
Fabrice Bureau
& Christophe J Desmet
Affiliations
Contributions
Corresponding authors
Nature Medicine 17, 996–1002 (2011) doi:10.1038/nm.2403 Received 11 February 2011 Accepted 19 May 2011 Published online 17 July 2011
Abstract
Abstract•
References•
Author information•
Supplementary information
Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination, although their mechanisms of action are poorly understood. Here we report that, in mice, alum causes cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal mediating alum adjuvant activity. Furthermore, we propose that host DNA signaling differentially regulates IgE and IgG1 production after alum-adjuvanted immunization. We suggest that, on the one hand, host DNA induces primary B cell responses, including IgG1 production, through interferon response factor 3 (Irf3)-independent mechanisms. On the other hand, we suggest that host DNA also stimulates 'canonical' T helper type 2 (TH2) responses, associated with IgE isotype switching and peripheral effector responses, through Irf3-dependent mechanisms. The finding that host DNA released from dying cells acts as a damage-associated molecular pattern that mediates alum adjuvant activity may increase our understanding of the mechanisms of action of current vaccines and help in the design of new adjuvants.
...
www.nature.com...
BTW, to specify as to what the above paper is referring to when they mention that aluminum adjuvants induce IgG1 and IgE production.
IgG1 (most abundant type of Immunoglobulin G)
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses.
...
www.sigmaaldrich.com...
IgE (Immunoglobulin E)
IgE not only provides protective immunity against helminth parasites but can also mediate the type I hypersensitivity reactions that contribute to the pathogenesis of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.
...
www.nature.com...
originally posted by: ElectricUniverse
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome
Christopher Exley, Louise Swarbrick, Rhomain K. Gherardi, Francois-Jérôme Authier
Received: August 28, 2008; Accepted: September 4, 2008; Published Online: November 12, 2008
DOI: dx.doi.org...
Summary
Macrophagic myofasciitis and chronic fatigue syndrome are severely disabling conditions which may be caused by adverse reactions to aluminium-containing adjuvants in vaccines. While a little is known of disease aetiology both conditions are characterised by an aberrant immune response, have a number of prominent symptoms in common and are coincident in many individuals. Herein, we have described a case of vaccine-associated chronic fatigue syndrome and macrophagic myofasciitis in an individual demonstrating aluminium overload. This is the first report linking the latter with either of these two conditions and the possibility is considered that the coincident aluminium overload contributed significantly to the severity of these conditions in this individual. This case has highlighted potential dangers associated with aluminium-containing adjuvants and we have elucidated a possible mechanism whereby vaccination involving aluminium-containing adjuvants could trigger the cascade of immunological events which are associated with autoimmune conditions including chronic fatigue syndrome and macrophagic myofasciitis.
...
www.medical-hypotheses.com...(08)00493-3/abstract
BTW, has anyone noticed how "certain people" will resort to label those who disagree with them on issues such as this one as "anti-vaxers" etc, etc. They do this despite the fact that I never said that "all vaccines should be banned"... I merely have stated and posted evidence that indicates that vaccines which have certain compounds such as "ethylmercury, and aluminum" are not as safe as "some people claim they are... Notice how they do this even when there is evidence that such disagreement with them has merit...
As for whether or not the nurse had a right to refuse the flu vaccine... She was pregnant, and even had a doctor's exemption to the vaccine... She, alongside many other nurses as well as doctors, did her research and made an informed decision. However, as we can see there are people who despite whatever evidence is presented will only continue trying to claim that "only they" are capable of knowing what doctor or researcher is able to make an informed decision on this topic...
Despite the plethora of evidence which shows the compounds such as aluminum adjuvants and ethyl-mercury in some vaccines are not "as safe as people are led to believe" these people will only continue trying to deny all evidence or any, and all arguments that would defy "these people's beliefs"...
originally posted by: ElectricUniverse
Plasma aluminum is a risk factor for oxidative stress and inflammation status in hemodialysis patients
Chih-Hung Guo, Chia-Liang Wang
Institute of Biomedical Nutrition, Hung Kuang University, Taichung 433, Taiwan, ROC
Department of Nephrology, Kuang-Tien General Hospital, Taichung 433, Taiwan, ROC
Received 9 February 2011, Revised 11 August 2011, Accepted 14 August 2011, Available online 25 August 2011
DOI: 10.1016/j.clinbiochem.2011.08.1132
Abstract
Objectives
The association between aluminum (Al), essential trace metals, oxidative stress, and inflammation status was evaluated in hemodialysis patients.
Design and methods
Biochemical parameters in blood were determined in long-term hemodialysis patients (n = 69) and age- and sex-matched healthy individuals (n = 30).
Results
Compared with healthy subjects, patients had significantly higher concentrations of plasma Al. Elevated Al was negatively associated with the essential metals zinc, selenium, and iron. Al concentrations were strongly and positively correlated with contents of the oxidation products malondialdehyde and protein carbonyl. Inverse relationships were observed between Al concentrations and reduced concentrations of glutathione, β-carotene, vitamin C, and vitamin E. Patients were also observed to have significantly increased production values of plasma high-sensitivity C-reactive protein, tumor necrosis factor-α, and interleukin-5.
Conclusion
An increased plasma Al concentration is associated with disturbed concentrations of essential metals, increased oxidative stress, and increased inflammation status in hemodialysis patients
...
www.sciencedirect.com...
Hippocampal neuronal metal ion imbalance related oxidative stress in a rat model of chronic aluminum exposure and neuroprotection of meloxicam
Lijuan Yu1, Rong Jiang2, Qiang Su1, Huarong Yu1* and Junqing Yang1*
* Corresponding authors: Huarong Yu [email protected] - Junqing Yang [email protected]
Author Affiliations
1 Department of Pharmacology, Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Medical College Rd. No 1, Chongqing Medical University, Chongqing 400016, P. R. China
2 Department of Stem Cells and Tissue Engineering, Chongqing Medical University, Chongqing 400016, P. R. China
For all author emails, please log on.
Behavioral and Brain Functions 2014, 10:6 doi:10.1186/1744-9081-10-6
The electronic version of this article is the complete one and can be found online at: www.behavioralandbrainfunctions.com...
Received: 2 September 2013
Accepted: 28 February 2014
Published: 11 March 2014
© 2014 Yu et al.; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (creativecommons.org...), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
Abstract
Neurodegenerative diseases remain a significant unresolved societal burden afflicting millions of people worldwide. Neurons in the brain are highly sensitive to oxidative stress, which can be induced by metal toxicity. In this paper, a chronic aluminum overload-induced model of neurodegeneration was used to investigate whether metal ions (Al, Fe, Mn, Cu and Zn)-related oxidative stress was involved in neurodegenerative mechanism and to identify the protective action of meloxicam against rat hippocampal neuronal injury. The metal ion contents, activity of superoxide dismutase (SOD), and content of malondialdehyde (MDA) were detected. The results showed that the spatial learning and memory (SLM) function was significantly impaired in chronic aluminum overload rats. Considerable karyopycnosis was observed in hippocampal neurons. The SOD activity was weakened and the MDA content increased both significantly. In the hippocampus, Al, Fe, Mn, Cu, and Zn contents increased by 184.1%, 186.1%, 884.2%, 199.4% and 149.2%, respectively. Meloxicam administration (without Al) had no effect compared with the control group, while meloxicam treatment with aluminum exposure significantly protected rats from SLM function impairment, neuron death, lower SOD activity, higher MDA content and brain metal ion imbalance. Our findings suggest that the cerebral metal ion imbalance-related oxidative stress is involved in mechanism of cerebral injury and neurodegeneration induced by chronic Al overload in rats, and that meloxicam protects neurons by reducing metal ion imbalance-related oxidative stress.
Keywords: Neurodegeneration; Metal ion; Meloxicam; Aluminum overload; Oxidative stress
...
www.behavioralandbrainfunctions.com...
originally posted by: Pardon?
I'm not sure if you've realised this but the paper you're quoting doesn't show any proof.
It only shows possibilities, hypotheses if you will.
Not really evidence is it?
Well, for you it might be but it's not scientific evidence.
Like I've said, the nurse broke the rules and was fired for it.
That's not infringing upon rights.
And her knowledge and belief about vaccines, like yours, was not based upon scientific evidence as her "research" wasn't very good.
And to turn your thinly veiled rant around...
Despite the thousands of studies which show that vaccines are safe and despite the overwhelming evidence that shows beyond all doubt that the amounts of adjuvants and ingredients in vaccines do not cause any harm there are still people who refuse to accept this and propagate an unsubstantiated belief system in place of science.
originally posted by: Pardon?
Yep.
You were right, they have absolutely nothing to do with vaccines.
Well done, something correct at last.
Just to rub it in, no relationship was found between autism and exposure to mercury, including in thimerosal, the mercury compound once used as a preservative for vaccines and products such as tattoo inks, but now discontinued for vaccines in the United States and Europe as a result of unproven fears.
...
Why was thimerosal removed from vaccines given to children?
•Although no evidence suggests that there are safety concerns with thimerosal, vaccine manufacturers have stopped using it as a precautionary measure.The only vaccine that still includes thimerosal as a preservative is the multi-dose inactivated influenza vaccine. There are other formulations of flu vaccine that do not include thimerosal.
...
...
Meningococcal Polysaccharide Vaccine, Groups A, C, Y, W135 Combined
Menomune-A/C/Y/W-135
Sanofi Pasteur Inc.
Jan. 2009
Mueller Hinton casein agar, Watson Scherp casamino acid media distilled water, thimersol, polysaccharide from serogroups A, C, Y, and w-135, mercury, lactose
...
...
Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)
ActHIB
Sanofi Pasteur, Inc.
May 2009
ammonium sulfate, formalin, Modified Mueller and Miller medium, saline diluent, formaldehyde sucrose, thimerosal, purified capsular polysaccharide
...
Influenza Virus Vaccine
Fluvirin
Novartis Vaccines and Diagnostics Limited
Feb. 26, 2013
allantoic cavity of embryonated hens' eggs, neomycin, polymyxin, betapropiolactone, nonylphenol ethoxylate, phosphate-buffered saline, thimerosal, egg proteins, polymyxin, neomycin, betapropiolactone, nonylphenol ethoxylate
originally posted by: ElectricUniverse
originally posted by: Pardon?
I'm not sure if you've realised this but the paper you're quoting doesn't show any proof.
It only shows possibilities, hypotheses if you will.
Not really evidence is it?
Well, for you it might be but it's not scientific evidence.
Like I've said, the nurse broke the rules and was fired for it.
That's not infringing upon rights.
And her knowledge and belief about vaccines, like yours, was not based upon scientific evidence as her "research" wasn't very good.
And to turn your thinly veiled rant around...
Despite the thousands of studies which show that vaccines are safe and despite the overwhelming evidence that shows beyond all doubt that the amounts of adjuvants and ingredients in vaccines do not cause any harm there are still people who refuse to accept this and propagate an unsubstantiated belief system in place of science.
First of all your whole argument, among some other people, has been that "vaccines are completely safe and there is no proof that they are not"... I have presented several research papers and doctors and specialists who refute your claims.
Some doctors and researchers say there are more questions than others, and others along their research show that the adjuvants and other compounds such as ethyl mercury in vaccines are not safe... I have NEVER written that "all research agrees that vaccines are not safe"... What I have stated time and again is that there is research that shows "vaccines with aluminum adjuvants and other compounds like ethyl-mercury are not as safe as people like you proclaim they are.
There is no question that there are vaccines which are needed, and there are vaccines that do not contain either as much, or any aluminum adjuvants or ethyl-mercury. Children these days are receiving more vaccines than in years past. Research shows that aluminum adjuvants, and other compounds like ethyl-mercury cause oxidative stress, and inflammation among other symptoms which are also symptoms found in neurological disorders and other health related illnesses which has been at an exponential increase.
I know that there are doctors and even specialists who claim "all vaccines are safe and aluminum adjuvants alongside other compounds are safe"... But guess what?... For every doctor and specialist who claims that vaccines are safe I can show you another doctor, or specialist who says they are not as safe and that parents should request that their children get vaccines that do not contain aluminum adjuvants or ethyl-mercury...
BTW, like I have already shown, ethyl-mercury was supposed to have been completely banned from vaccines yet to this day 60% of flu vaccines, alongside some others, still contain ethylmercury. All multi-dose flu shots STILL CONTAIN ETHYL-MECURY despite the claims, which is more of a lie, from some people that claim vaccines do not contain ethyl-mercury anymore...
originally posted by: ElectricUniverse
originally posted by: Pardon?
Yep.
You were right, they have absolutely nothing to do with vaccines.
Well done, something correct at last.
They?... It was ONE research and I posted it to show part of other evidence which proves aluminum adjuvants cause oxidative stress, and inflammation among other detrimental effects on human health.
Like I knew it you try to twist anything and everything but that only shows how desperate people like you are to deny what is right in front of you.
BTW, to prove my point let me show you how that link you gave lies to your face and people like you are dumb enough to believe them for "whatever motive" you might have.
At the end of that link you gave which is more opinion than fact, the author of that link you gave, "Stephen Luntz", states and I quote...
Just to rub it in, no relationship was found between autism and exposure to mercury, including in thimerosal, the mercury compound once used as a preservative for vaccines and products such as tattoo inks, but now discontinued for vaccines in the United States and Europe as a result of unproven fears.
www.iflscience.com...
When the FACT is actually the contrary to what he, and you "claim"...
...
Why was thimerosal removed from vaccines given to children?
•Although no evidence suggests that there are safety concerns with thimerosal, vaccine manufacturers have stopped using it as a precautionary measure.The only vaccine that still includes thimerosal as a preservative is the multi-dose inactivated influenza vaccine. There are other formulations of flu vaccine that do not include thimerosal.
...
www.cdc.gov...
Not to mention that the CDC and FDA claim that they test all batches of vaccines before they are given to the public despite the fact that in several instances contaminated vaccines have been released to the public and have infected millions and neither the CDC nor the FDA did tests on those vaccines because if they did they would have found that the vaccines were contaminated. Then there is also the fact that neither the CDC nor the FDA test vaccines that have been "purified' as claimed by vaccine manufacturers as there is no protocol neither for the FDA or CDC to "test" whether those vaccines have actually been "purified" of adjuvants or other toxic compounds.
For crying out loud I even gave links to the ingredients that vaccine manufacturers still use TO THIS DAY and they clearly state that "multi-dose flu shot vaccines still contain ethyl-mercury"... Yet you, and some other people, want to claim that they don't...
Some other vaccines that still use ethyl-mercury.
...
Meningococcal Polysaccharide Vaccine, Groups A, C, Y, W135 Combined
Menomune-A/C/Y/W-135
Sanofi Pasteur Inc.
Jan. 2009
Mueller Hinton casein agar, Watson Scherp casamino acid media distilled water, thimersol, polysaccharide from serogroups A, C, Y, and w-135, mercury, lactose
...
vaccines.procon.org...
...
Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)
ActHIB
Sanofi Pasteur, Inc.
May 2009
ammonium sulfate, formalin, Modified Mueller and Miller medium, saline diluent, formaldehyde sucrose, thimerosal, purified capsular polysaccharide
...
Influenza Virus Vaccine
Fluvirin
Novartis Vaccines and Diagnostics Limited
Feb. 26, 2013
allantoic cavity of embryonated hens' eggs, neomycin, polymyxin, betapropiolactone, nonylphenol ethoxylate, phosphate-buffered saline, thimerosal, egg proteins, polymyxin, neomycin, betapropiolactone, nonylphenol ethoxylate
vaccines.procon.org...
I have to wonder how you can believe "such a claim' when they are lying to your face. Well, you seem to be doing the same here so I guess that answers why you would believe "such lies"...
originally posted by: ElectricUniverse
a reply to: Pardon?
I can say the same for you. But again, you keep showing to want to dismiss anything and everything that doesn't conform to your belief. I presented real research from several peer-reviewed sources, and dozens of doctors and specialists, yet you dismiss it all simply because you don't want to entertain the possibility that you are wrong.
originally posted by: Pardon?
Nope.
Wrong again.
I've explained why the "science" you're citing is unacceptable yet for some bizarre reason you keep on promoting it.
And you seem incapable of understanding why it's unacceptable.
That's indicative of a belief system, not science.
I'm more than happy to change what I know based upon verifiable and pertinent research.
Are you?