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Polyomaviruses are DNA-based (double-stranded DNA, ~5000 base pairs, circular genome), small (40-50 nanometers in diameter), and icosahedral in shape, and do not have a lipoprotein envelope. Moreover, the genome possess early and late genes, contributing to its complex transcription program. They are potentially oncogenic (tumor-causing); they often persist as latent infections in a host without causing disease, but may produce tumors in a host of a different species, or a host with an ineffective immune system. The name polyoma refers to the viruses' ability to produce multiple (poly-) tumors (-oma).
J Neurovirol. 2010 Mar;16(2):141-9.
Association of autism with polyomavirus infection in postmortem brains.
Lintas C, Altieri L, Lombardi F, Sacco R, Persico AM.
Laboratory of Molecular Psychiatry and Neurogenetics, University Campus Bio-Medico, Rome, Italy.
Abstract
Autism is a highly heritable behavioral disorder. Yet, two decades of genetic investigation have unveiled extremely few cases that can be solely explained on the basis of de novo mutations or cytogenetic abnormalities. Vertical viral transmission represents a nongenetic mechanism of disease compatible with high parent-to-offspring transmission and with low rates of disease-specific genetic abnormalities. Vertically transmitted viruses should be found more frequently in the affected tissues of autistic individuals compared to controls.
Our initial step was thus to assess by nested polymerase chain reaction (PCR) and DNA sequence analysis the presence of cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2), human herpes virus 6 (HHV6), BK virus (BKV), JC virus (JCV), and simian virus 40 (SV40) in genomic DNA extracted from postmortem temporocortical tissue (Brodmann areas 41/42) belonging to 15 autistic patients and 13 controls.
BKV, JCV, and SV40 combined are significantly more frequent among autistic patients compared to controls (67% versus 23%, respectively; P < .05). The majority of positives yielded archetypal sequences, whereas six patients and two controls unveiled single-base pair changes in two or more sequenced clones. No association is present with the remaining viruses, which are found in relatively few individuals (N
Originally posted by Neopan100
reply to post by Annee
I totally agree...I mean look at how many people have received the vaccines to those with autism..very rare..luck of the draw at most..I was born in 75' and everyone I know got the cocktail of vaccines..i didn't get the small pox vac. but all the others I did..and I got boosters in HS and in College. I got a booster of Hep when I worked at a dermatology office about 10 years ago.
I don't know a single person with autism..not one..ever.
Originally posted by Annee
Originally posted by Neopan100
reply to post by Annee
I totally agree...I mean look at how many people have received the vaccines to those with autism..very rare..luck of the draw at most..I was born in 75' and everyone I know got the cocktail of vaccines..i didn't get the small pox vac. but all the others I did..and I got boosters in HS and in College. I got a booster of Hep when I worked at a dermatology office about 10 years ago.
I don't know a single person with autism..not one..ever.
One reason there is an increase in Autism is the range of what falls under the umbrella has increased.
Children are being screened as early as 18 months old. Today the kid who sat daydreaming in school would fall under the Autism umbrella.
They actually changed the name (which I can't remember now) - - - because Autism is misleading.
It involves chemical processing in the brain. There is one form that strikes about age 5. The child can be perfectly normal then become severely Autistic. Which could make you think something was done to your child to cause it.
Its also found to be hereditary.
Originally posted by syrinx high priest
so did the OP return ?
I'd like to know the age of the father
recent research has identified that as a risk factor
Originally posted by Scouser640
I haven't read every post, so I don't know if this hasd already been said - but - THINK ABOUT IT!! A cocktail of chemicals, toxins, bacteria and animal bits are injected DIRECTLY in to the bloodstream of a child, over and over again. Why would anyone think this is a good idea? It just blows my mind that anyone would roll up their sleeves for this. I have three kids - none of them have had a shot, and never will on my watch.
Originally posted by Ghost375
Nearly every child is vaccinated these days....
So drawing a causal relationship isn't smart....
There are countless studies that analyze the data with statistical analysis, and do not find a significant relationship between vaccines and autism.
Wouldn't everyone be getting autism if vaccines truly caused autism, seeing as 90%+ of children are vaccinated?
Now there is an increase of autism rates, don't get me wrong. But it is most likely caused by something else in the environment.
The vast majority of studies show that the increase isn't due to vaccines.
I've taken a look at some of the studies that show the increase is due to vaccines, and they are FLAWED studies, not to mention they are in the minority. The vast majority of studies show no increased risk of autism due to vaccination.
Using anecdotes is VERY poor science, fyi.