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Originally posted by soficrow
reply to post by Maslo
fat cells in (primary) obesity are still safely under the influence of regulatory factors
Really? Safely? Ref?
It is the mainstream opinion, do I really have to source it?
But here is one:
www.ncbi.nlm.nih.gov...
Most cases of obesity are caused primarily by imbalance in energy intake and expenditure, not mutations of regulatory genes as in cancer.
The researchers found that Ad36 infection increased fat storage in cells .... Ad36 did this by turning on genes known to be involved in an adipogenic (fat-producing) cascade, including C/EBP, PPAR2, aP2 and G3PDH.
What this means is Ad36 strongly induces weight gain...
ScienceDaily (Sep. 20, 2010) — The emerging idea that obesity may have an infectious origin gets new support in a cross-sectional study by University of California, San Diego School of Medicine researchers who found that children exposed to a particular strain of adenovirus were significantly more likely to be obese.
I'm not Obese, but I am overweight. A lot. I agree with you that food is medicine...but what kind of food? Is it true that consuming any form of animal fat (meat, milk, eggs, etc) is bad? Or this is a myth? I try to avoid GMO as much as I can but unless you grow your own food you can never be 100% certain.
Obesity: Often An Infectious Disease
In the book we attribute obesity mainly to food toxins and malnutrition. Both are well attested as causes of obesity in animals:
The easiest way to induce obesity in animals is to feed them a carb toxin and a fat toxin – e.g. wheat, fructose, or alcohol with polyunsaturated fats or hydrogenated trans-fats. ....
[NOTE] …there are thin diabetics and obese non-diabetics. How is it that the same cause can produce different diseases?
One thing the adenovirus work is telling us is that the nature of one’s chronic infections may determine how bad diets translate into disease. Toxic and malnourishing diets make disease inevitable, but which disease depends on which pathogens happen to be around to exploit the bad diet and weakened immunity.
you're still not presenting anything that justifies calling it a cancer.
What sort of conspiracy, scandal or cover-up are you advocating here? Do you have any evidence?
There was no obesity in Bergen-Belsen.
Originally posted by DeReK DaRkLy
reply to post by soficrow
Can you prove it? Can you provide any evidence to show that "the cell formations/deformations in cancer happen for very different reasons"?
Umm.. because all fat isn't cancerous and all cancer isn't in fat cells. Cells are not mutated in fat production. Fat is normal and healthy in the correct amount...
Cancer is an anomaly that happens to a cell, but fat production is a normal process.
All they have in common is that in both cancer and obesity there is an excess occurrence.
Originally posted by soficrow
Only about 20% of Americans are obese but over 65% have “obesity-related” health conditions. The added 45% may be in good shape but technically, their conditions are “obesity-related.” Blood vessel diseases, high blood pressure, diabetes and many types of cancer are on the “obesity-related” list, for example.
Obesity is pandemic - people in undeveloped nations suffering from malnutrition and starvation are obese
FYI - the next year, in 2009, research from Wayne University proved that a common cold virus called Ad36 caused fat cells to store more fat.
Originally posted by Maslo
reply to post by soficrow
Obesity is pandemic - people in undeveloped nations suffering from malnutrition and starvation are obese
People suffering from malnutrition and starvation are obese? Citation needed for such contradictory statement.
June 4, 2012
Homeless and Overweight: Obesity Is the New Malnutrition
A new survey finds that one in three homeless people in Boston are clinically obese, a number that casts in relief the strange reality of food in the 21st century United States.
Not long ago, malnourishment was embodied by emaciation. Now it’s far more likely to be hidden in folds of fat.
....The findings are the latest and most dramatic illustration of what’s called the “hunger-obesity paradox,” a term coined in 2005 by neurophysiologist Lawrence Scheier to describe the simultaneous presence of hunger and obesity.
August 4, 2005
Obesity and malnutrition exist side-by-side
While nutritional status has improved worldwide over the past fifty years, new nutrition-related problems have also emerged. In an article recently published in The Journal of Nutrition, Eileen Kennedy DSc, RD, dean of the Friedman School of Nutrition Science and Policy at Tufts University, offers an updated view of global nutrition. She describes how global demographic, epidemiological, and nutritional transitions have led to a unique situation in which food insecurity (uncertain or scarce access to safe and healthy food) exists side by side with problems of obesity and chronic nutrition-related diseases, even in the same household. Kennedy, former acting undersecretary at the United States Department of Agriculture, calls for new research to address this emerging and complex new problem.
Nutrient inadequacy in obese and non-obese youth.
Even though children may consume an excess of energy, they may not be meeting all of their micronutrient needs.
How Malnutrition Causes Obesity
Americans are overfed and undernourished. That's right, the most obese children and adults in the country are also the most nutritionally deficient...
The Great Chinese Famine that affected the Chongqing population during 1959–1961 leads to shorter and overweight females, and the former is a risk factor for increased BMI in Chongqing. Second, the famine seems to be producing shorter but slimmer males in Chongqing. Furthermore, toddler's and maternal's malnutrition during the famine had important late consequences on the health status.
FYI - the next year, in 2009, research from Wayne University proved that a common cold virus called Ad36 caused fat cells to store more fat.
Interesting research, but far from proving your point. Various factors can contribute to the individual risk of obesity, but the main cause is still unbalanced diet.
There are many people with Ad36 strain that are not obese - because they eat healthy. Its maybe a contributing factor, or one that can make obesity worse - but its not a cause.
…there are thin diabetics and obese non-diabetics. How is it that the same cause can produce different diseases?
One thing the adenovirus work is telling us is that the nature of one’s chronic infections may determine how bad diets translate into disease. Toxic and malnourishing diets make disease inevitable, but which disease depends on which pathogens happen to be around to exploit the bad diet and weakened immunity.
And similarly, not all cell proliferation (even induced by viruses) is cancer. It must be irreversible and uncontrolled for it to be cancer. From your linked article, it appears the virus upregulates the pre-adipose cells proliferation, but they are still under control, do not proliferate autonomously and always develop into normal adipocytes. It appears to be epi-genetic, not caused by irreversible mutation in the regulatory genes (deactivation of anti-oncogenes, activation of pro-oncogenes) like in cancer.
We Must Break the Vicious Cycle of Obesity, Malnutrition and Poverty
South Africa has some of the highest levels of obesity in the world, together with exceptionally high rates of poverty. These two issues are linked in a vicious, attritional cycle.
At first glance it appears counter-intuitive to consider that poverty and obesity could be associated. The fact is that poverty is intimately correlated to several non-communicable diseases. Numerous international studies have shown how obesity and its morbid fellow travellers, hypertension and diabetes, stalk the health of the poorest and most marginalised sectors of society.
As a developing nation, with increasing urbanisation, South Africa provides an exemplary case of the paradox of obesity amongst poverty. So how does this apparent contradiction exist and perpetuate?
When most people consider the effect of poverty, the initial image is of an emaciated, stunted figure, perhaps with a tell-tale red tint in her hair. While this is the most visible impact on children, research shows us that the long-term impacts of poverty are even more profound and menacing.
Poorly nourished infants have been found to be predisposed to obesity in later life. This occurs by interference with the genetic programming of the body, mainly in utero. If a mother does not receive adequate nutrition, the lot of her baby can become forever compromised. This is how the tragedy of poverty is perpetuated, inter-generationally. This occurs directly through malnutrition, as well as through other rather more sinister mechanisms. .....
This SACSIS article is licensed under a Creative Commons License by The South African Civil Society Information Service (www.sacsis.org.za).
This is still not addressing your assertion that obesity is a form of cancer.
Don't start calling it a disease. The disease is that people eat incessantly and live horrible lifestyles.
Poorly nourished infants have been found to be predisposed to obesity in later life. This occurs by interference with the genetic programming of the body, mainly in utero. If a mother does not receive adequate nutrition, the lot of her baby can become forever compromised. This is how the tragedy of poverty is perpetuated, inter-generationally. This occurs directly through malnutrition, as well as through other rather more sinister mechanisms. .....
The Great Chinese Famine that affected the Chongqing population during 1959–1961 leads to shorter and overweight females, and the former is a risk factor for increased BMI in Chongqing. Second, the famine seems to be producing shorter but slimmer males in Chongqing. Furthermore, toddler's and maternal's malnutrition during the famine had important late consequences on the health status.
Focus, child. You might go somewhere with your thoughts.
…most industrial foods carry residual levels of these chemicals and pesticides, many which are known endocrine disruptors. Endocrine or hormone disruptors are closely associated with serious negative health impacts, including obesity, diabetes and hypertension. This chemical exposure is known as our body burden.
So here we effectively have a double whammy. The poor eat food which predisposes them to poor health, on top of another, existing predisposition, genetically caused by malnutrition in the uterus or as infants.
What Is Cancer?
Cancer is the general name for a group of more than 100 diseases. Although there are many kinds of cancer, all cancers start because abnormal cells grow out of control.
Defining Cancer
Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems.
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer that begins in basal cells of the skin is called basal cell carcinoma.
Cancer types can be grouped into broader categories. The main categories of cancer include:
Carcinoma - cancer that begins in the skin or in tissues that line or cover internal organs.
Sarcoma ...begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.
Leukemia ...starts in blood-forming tissue such as the bone marrow ...
Lymphoma and myeloma ...begin in the cells of the immune system.
Central nervous system cancers ...begin in the tissues of the brain and spinal cord.