It looks like you're using an Ad Blocker.
Please white-list or disable AboveTopSecret.com in your ad-blocking tool.
Thank you.
Some features of ATS will be disabled while you continue to use an ad-blocker.
Originally posted by IgnoranceIsntBlisss
You could post the abstracts.
What would also be helpful are some numbers. You can post numbers from documents etc research.
< Previous Abstract | Next Abstract >
Health Physics:
April 2007 - Volume 92 - Issue 4 - pp 349-357
doi: 10.1097/01.HP.0000251248.23991.35
Paper
CYTOGENETIC OBSERVATIONS IN HUMAN PERIPHERAL BLOOD LEUKOCYTES FOLLOWING IN VITRO EXPOSURE TO THz RADIATION: A PILOT STUDY
Zeni, O; Gallerano, G P.; Perrotta, A; Romanò, M; Sannino, A; Sarti, M; D'Arienzo, M; Doria, A; Giovenale, E; Lai, A; Messina, G; Scarfì, M R.
Abstract
Emerging technologies are considering the possible use of Terahertz radiation in different fields ranging from telecommunications to biology and biomedicine. The study of the potential effects of Terahertz radiation on biological systems is therefore an important issue in order to safely develop a variety of applications. This paper describes a pilot study devoted to determine if Terahertz radiation could induce genotoxic effects in human peripheral blood leukocytes. For this purpose, human whole blood samples from healthy donors were exposed for 20 min to Terahertz radiation. Since, to our knowledge, this is the first study devoted to the evaluation of possible genotoxic effects of such radiation, different electromagnetic conditions were considered. In particular, the frequencies of 120 and 130 GHz were chosen: the first one was tested at a specific absorption rate (SAR) of 0.4 mW g-1, while the second one was tested at SAR levels of 0.24, 1.4, and 2 mW g-1. Chromosomal damage was evaluated by means of the cytokinesis block micronucleus technique, which also gives information on cell cycle kinetics. Moreover, human whole blood samples exposed to 130 GHz at SAR levels of 1.4 and 2 mW g-1 were also tested for primary DNA damage by applying the alkaline comet assay immediately after exposure. The results obtained indicate that THz exposure, in the explored electromagnetic conditions, is not able to induce either genotoxicity or alteration of cell cycle kinetics in human blood cells from healthy subjects.
©2007Health Physics Society
Home > April 2007 - Volume 92 - Issue 4 > CYTOGENETIC OBSERVATIONS IN HUMAN PERIPHERAL BLOOD LEUKOCYTE...
Han et al (2000) compared time-domain transmission THz imaging with imaging using near-infrared pulses. As expected, the lower scattering meant that the THz attenuation image showed significantly enhanced contrast in an image of ametal structure in a sample of pork-fat
tissue. Research with tissue is concentrated in two areas; first, on diagnostic applications close to the body surface, because these are likely to be the first performed as a result of the strong water absorption that limits the depth of penetration. Second, researchers have considered
tissue that currentlymust be examined in vitro, butwhich, with technological advances, should in future be accessible to THz irradiation.
Although water absorption limits the depth of tissue that may be imaged, the presence of water may have its advantages. In particular, it may be possible to exploit the sensitivity of THz absorption to water content and use the degree of hydration of tissue as a measure of disease state. This was the case in the earliest work with tissue reported by Mittleman et al
(1996, 1999). Preliminary work with burnt chicken skin suggested that TPI may have applications in burn diagnostics and wound healing.
5. Conclusions and future work
The THz region of the EM spectrum was very difficult to explore, until recent advances made the generation and detection of the radiation possible. Many details of the interaction between THz radiation and biological tissue require elucidation. Interaction between the radiation and biological tissue may be exploited in the production of images, but it is possible that the development of high-resolution THz spectroscopy of small tissue samples will yield greater benefits, particularly as a probe for molecular dynamics, including the behaviour of DNA. However, much experimental work remains to be undertaken if useful information on
biological tissue structure content and function is to be gained.
INSTITUTE OF PHYSICS PUBLISHING PHYSICS IN MEDICINE AND BIOLOGY
Phys. Med. Biol. 47 (2002) R67–R84 PII: S0031-9155(02)31211-9
TOPICAL REVIEW
An introduction to medical imaging with coherent
terahertz frequency radiation
A J Fitzgerald1, E Berry1, N N Zinovev2, G C Walker1, M A Smith1
and J M Chamberlain2
1 Academic Unit of Medical Physics and Centre of Medical Imaging Research,
University of Leeds, Leeds, LS1 3EX, UK
2 Institute of Microwaves and Photonics, University of Leeds, Leeds, LS2 9JT, UK
Received 26 November 2001, in final form 23 January 2002
Published 20 March 2002
Online at stacks.iop.org/PMB/47/R67
Abstract
Methods have recently been developed that make use of electromagnetic
radiation at terahertz (THz) frequencies, the region of the spectrum between millimetre wavelengths and the infrared, for imaging purposes. Radiation at these wavelengths is non-ionizing and subject to far less Rayleigh scatter than visible or infrared wavelengths, making it suitable for medical applications. This paper introduces THz pulsed imaging and discusses its potential for in vivo medical applications in comparison with existing modalities.
Measurements of the absorption coefficient of water show that it strongly attenuates signals in the THz region, with broad absorption peaks at 6 THz and 19.5 THz (Kindt and Schmuttenmaer 1996). This has strong implications for the use of TPI for medical imaging. On one hand the high absorption limits the depth of penetration of signals through
tissues with high moisture content, on the other, it makes THz methods very sensitive to changes in the water content of tissue. Measurements by Bezant (2000) demonstrated that a R70 Topical Review
THz pulse could be detected after penetration through at least 1.5 mm of moist skin tissue when the detection signal-to-noise ratio (SNR) is 500 to 1. This is considerably further than through water alone. Mittleman et al (1996) addressed the question of sensitivity to water content and suggested that for an SNR of 100, a minimum concentration given by n × x = 1016 cm−2 can be detected, where n is the density of water molecules and x is the path length.
5. Developments
TPI is in the very earliest stages of its development, but it is possible to suggest how the field may mature. Endoscopic imaging by fibre optic delivery would allow access to tissues away from the surface of the body. The first steps towards this goal have been made with
the development of waveguides for THz radiation (Gallot et al 2000) and with the use of fibre optics in THz delivery (Johnson et al 2000). There is potential to enhance the performance of Topical Review R81
conventional excisional biopsies by using terahertz image and spectroscopic guidance to select biopsy sites. Itmay be possible to replace conventional biopsy by in situ spectroscopic analysis and to guide interventional procedures using terahertz technology. Intravascular imaging offers the promise of atherosclerotic plaque characterization, which is of great interest in the carotid artery. However, considerable technological developments are required for THz techniques to be used in the coronary arteries, where a resolution of 30–100 μm is necessary to resolve the layered structure of the vessel wall (Foster et al 2000). More rapid data acquisition opens up possibilities associated with the assessment of function and physiological processes, which can be of value in monitoring drug efficacy.
Although for many potential applications there are a number of alternative technologies, none has yet emerged as the ideal tool. It is inevitable that TPI will be added to the clinician’s armamentarium and be valued for the complementary information it can provide.
Multimodality developments may provide the greatest advances, by adding to existing techniques this new compact, non-contact imaging tool that is free from concerns about ionizing radiation hazards and making use of its potential for spectroscopic analysis coupled with low levels of scattering.
Originally posted by PreyBird
reply to post by IgnoranceIsntBlisss
This is by no means an attack on your person, but are you Conservative? Just saying.
If you have a better solution to the said issue,why not study both sides and come to a just conclusion without bringing your emotions into it instead of reiterating someone elses OPINION... . Remember, most ideas are put in place to protect us from failure, but every once in a while, that small percentage of failed ideas can slip through the cracks. Us humans are, by no means, perfect. BUT at least we try.
Originally posted by IgnoranceIsntBlisss
reply to post by Maybe...maybe not
Ok thanks for getting us somewhere with those abstracts, but now what I think we need is wattage levels to cause DNA disruption, at x distances and durations, and then we compare that to what is found inside those big metal looking boxes with the window we see in the photos.
I'm also curious the implications of the new papers explaination of why past studies had problems compared to their new technique, and if that applies to the herein-relevant abstracts you've posted. If you could be so kind...
Height: 2665.0 mm (104.9")
Width: 1947.8 mm (76.7")
Depth: 2651.1 mm (104.4")
Weight: 816 kg (1800 lbs)
Power: 100 VAC - 240 VAC / 1900 Watts Peak
50 hz - 60 hz
Temperature: 0° C to 35° C (32° F to 104° F)
Humidity: 5 – 95% non-condensing
Power Supply
External Supply, 100 to 240 VAC, 47-63 Hz, 120 W; output 12 VDC, 10 A
Detector Millimeter Wave Frequency
80 to 100 GHz (90 GHz center frequency,
20 GHz bandwidth)
Operating Temperature
-10°C to 50°C (14°F to 122°F)
Operating Humidity
0 to 100% RH condensing (outdoor use)
Dimensions (H X W X D):
83.8 cm x 34.5 cm x 34.9 cm (33.0 in x 13.5 in x 13.7 in) excluding mounting bracket
Originally posted by endisnighe
I had a feeling these scanners would not be safe. Hell, might as well set up x ray machines.
Remember the movie where they guy stuffed the bomb up the bad guy's bum.
I cannot remember it, I picture the guy from The Transporter for some reason.
Anyway, what will stop a terrorist from doing that.
Next we will have x ray machines set up.
WTH.
Originally posted by DCPatriot
Originally posted by endisnighe
I had a feeling these scanners would not be safe. Hell, might as well set up x ray machines.
Remember the movie where they guy stuffed the bomb up the bad guy's bum.
I cannot remember it, I picture the guy from The Transporter for some reason.
Anyway, what will stop a terrorist from doing that.
Next we will have x ray machines set up.
WTH.
It was Denzel Washington in MAN ON FIRE...playing role of bodyguard for little girl who appears to be kidnapped.
www.imdb.com...
Security and intelligence experts are deeply worried by a new development in suicide bombing, the BBC has learned. It has emerged that an al-Qaeda bomber who died last month while trying to blow up a Saudi prince in Jeddah had hidden the explosives inside his body. Only the attacker died, but it is feared that the new development could be copied by others. Experts say it could have implications for airport security, rendering traditional metal detectors "useless".