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originally posted by: Kenzo
a reply to: Maxmars
Ivermectin effect™ goes much further away than just covid , it has anti-cancer effect also ,hence the big fight against it, since cancer is also big $$$$$$$ .
Therapeutics and repurposed drugs for the treatment of cancer
In other words , Ivermectin seem to be quite good drug for prevention/treatment of cancers
Abstract Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. A randomized, double-blind, placebo-controlled trial was conducted to determine the rapidity of viral clearance and safety of ivermectin among adult SARS-CoV-2 patients. The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups: oral ivermectin alone (12 mg once daily for 5 days), oral ivermectin in combination with doxycycline (12 mg ivermectin single dose and 200 mg doxycycline on day 1, followed by 100 mg every 12 h for the next 4 days), and a placebo control group. Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27). There were no severe adverse drug events recorded in the study. A 5-day course of ivermectin was found to be safe and effective in treating adult patients with mild COVID-19. Larger trials will be needed to confirm these preliminary findings.
In reality, ivermectin’s role in human medicine began in 1978 inside the
MSDRL, with William Campbell being the driving force behind the investigation
of the potential for human use.....
In 1981, MSDRL’s Mohammed Aziz, previously of the WHO, undertook a small clinical trial of ivermectin in patients with safety paramount. Commencing with a very low dose of 5 µg/kg, he found that a single dose of 30 µ/kg substantially decreased skin microflariae and confirmed that the effect lasted for at least 6 months, with no serious adverse events. His tests concluded that doses up to 200 µg/kg were safely tolerated.....
Merck received approval from French authorities in 1987 allowing human use of ivermectin. In a hitherto unprecedented gesture, immediately following registration, ivermectin (branded as Mectizan®) was donated free of charge by Merck & Co. Inc., under the direction of Roy Vagelos (Fig. 24), for the treatment of Onchocerciasis (River Blindness), with KI foregoing all royalties. The donation was for as long as the drug was required, in the amounts that were needed. This represented the first such large-scale drug donation initiative and it has resulted in the world’s largest, longest-running and most successful drug donation programme.
www.nobelprize.org...
originally posted by: TheResidentAlien
a reply to: Ophiuchus1
3mg in a human is quite literally no more than a placebo. Like taking a half shot of whiskey every morning expecting to eventually get drunk.
For comparison, the recommended dose for a freaking cat is .5mg - 1.5mg PER KILO!
End result: Using it as a frontline drug for covid may have ended up killing more in the long term.