Promising New Vaccine from Walter Reed Enters Trials

The vaccine, called spike ferritin nanoparticle (SpFN), stands out in the COVID-19 vaccine landscape. Its multi-faced sphere design allows repetitive, ordered presentation of the coronavirus spike protein to the immune system, a strategy that may help provide broader protection.

“Even before recent COVID-19 variants were identified, our team was concerned about the emergence of new coronaviruses in human populations, a threat that has been accelerating in recent years” said Dr. Kayvon Modjarrad, director of the Emerging Infectious Diseases Branch (EIDB) at WRAIR who leads the Army’s COVID-19 vaccine research efforts and co-invented the vaccine with WRAIR structural biologist Dr. Gordon Joyce, an employee of the Henry M. Jackson Foundation for the Advancement of Military Medicine. “That’s why we need a vaccine like this: one that has potential to protect broadly and proactively against multiple coronavirus species and strains.

this sounds promising... might end up working better than what we have now, and with the flexibility to tackle other coronaviruses as well. that would be great considering covid probably won't be the last threatening coronavirus we face. i'll be following these trials with some interest.

Phase 1 Clinical Trial of WRAIR-developed COVID-19 Vaccine Begins

originally posted by: fiverx313

The vaccine, called spike ferritin nanoparticle (SpFN), stands out in the COVID-19 vaccine landscape. Its multi-faced sphere design allows repetitive, ordered presentation of the coronavirus spike protein to the immune system, a strategy that may help provide broader protection.

“Even before recent COVID-19 variants were identified, our team was concerned about the emergence of new coronaviruses in human populations, a threat that has been accelerating in recent years” said Dr. Kayvon Modjarrad, director of the Emerging Infectious Diseases Branch (EIDB) at WRAIR who leads the Army’s COVID-19 vaccine research efforts and co-invented the vaccine with WRAIR structural biologist Dr. Gordon Joyce, an employee of the Henry M. Jackson Foundation for the Advancement of Military Medicine. “That’s why we need a vaccine like this: one that has potential to protect broadly and proactively against multiple coronavirus species and strains.

this sounds promising... might end up working better than what we have now, and with the flexibility to tackle other coronaviruses as well. that would be great considering covid probably won't be the last threatening coronavirus we face. i'll be following these trials with some interest.

Phase 1 Clinical Trial of WRAIR-developed COVID-19 Vaccine Begins

There are 11 different versions of the seasonal flu vaccine, in over 10 years of development, and the best we can achieve is 70% effectiveness.

a reply to: putnam6

and yet... the pfizer and moderna are 80% effective against catching it and 90% effective against getting severely ill.

pretty sure flu vaccines usually top out at 40-50% any given year and that's still a pretty big help fighting it.

can we cure cancer first or aids? I mean im cool with getting a cold

a reply to: fiverx313
why keep spinning the wheel on death...over a .01% chance of severe symptoms?

Promising?

The only thing promising about any of these damned things is that I promise they'll never get in my body.

a reply to: incoserv

Im with you on this one. none of these placebos will enter my body by my will.

originally posted by: BlueJacket
a reply to: fiverx313
why keep spinning the wheel on death...over a .01% chance of severe symptoms?

Real diseases are necessary to keep big pharma making incremental steps to ensure profit.
Fake diseases need many vaccines to keep making big pharma incremental steps to ensure profit.

They don't want to cure things, just seek to. And they are quite happy to keep inconsequential things at the fore of unprecedented vaccines - which ultimately, just might give them even more reason to seek a cure for something else.

a reply to: jerich0

Like i tell everybody there is no money in the healthy

originally posted by: MissCoyote
can we cure cancer first or aids? I mean im cool with getting a cold

plenty of scientists are working on those, actually.

BlueJacket
why keep spinning the wheel on death...over a .01% chance of severe symptoms?

well, because some of us have people in our lives who are vulnerable and we'd like to protect them too, and stop community spread and the disease mutating into something even worse. might be a pipe dream at this point considering the 25% level of vaccine resistance in the population, but i'm a dreamer

incoserv
Promising?

The only thing promising about any of these damned things is that I promise they'll never get in my body.

that's your choice and i support that. if you don't take an interest in the science of it, i'll make a note of that as well. thanks for your thoughts!

a reply to: MissCoyote

Brilliant point.

The answer is the economics of engineering flu/respiratory illness vaccines are more lucrative.

More people "catch" these illnesses (relative to say cancer) + the scientific research/problem is an easier nut to crack (much more time and money required to say inoculate against cancer vs COVID) makes this low hanging fruit for Big Pharma.

originally posted by: jerich0
Real diseases are necessary to keep big pharma making incremental steps to ensure profit.
Fake diseases need many vaccines to keep making big pharma incremental steps to ensure profit.

They don't want to cure things, just seek to. And they are quite happy to keep inconsequential things at the fore of unprecedented vaccines - which ultimately, just might give them even more reason to seek a cure for something else.

as i understand it, there are quite a few treatments that have been in the works, in testing and in trials... very unfortunately for early sufferers, in real-life trials. the development of treatments is somewhat different from the development of vaccines, and in pandemic situations it's actually very logical to pursue both, to try and get the spread under control and take some pressure off the healthcare system.

a reply to: fiverx313

CANT cure cancer BUT can whip up an unaccountable inoculation in less than a year for a variant of the common cold that has a 95% survival rate.

a reply to: fiverx313

The vaccine does not prevent you getting virus. Nor from spreading it. And while it might, in most cases (perhaps the 99.8% of those who would survive anyway?) prevent serious illness, what it actually does is allow asymptomatic people to meander around society, spreading it, should they be infectious.

So while someone feeling sick may stay at home and self quarantine, a vaccinated person will not. And you're worried about spreading it?

originally posted by: MissCoyote
a reply to: fiverx313

CANT cure cancer BUT can whip up an unaccountable inoculation in less than a year for a variant of the common cold that has a 95% survival rate.

nearly all researchers have gaps in funding and have to pause to pursue more. lots of $$$ was poured into this one... again... because there's a pandemic killing people and with one easy to spot root cause, unlike cancer.

originally posted by: fiverx313

originally posted by: MissCoyote
can we cure cancer first or aids? I mean im cool with getting a cold

plenty of scientists are working on those, actually.

BlueJacket
why keep spinning the wheel on death...over a .01% chance of severe symptoms?

well, because some of us have people in our lives who are vulnerable and we'd like to protect them too, and stop community spread and the disease mutating into something even worse. might be a pipe dream at this point considering the 25% level of vaccine resistance in the population, but i'm a dreamer

incoserv
Promising?

The only thing promising about any of these damned things is that I promise they'll never get in my body.

that's your choice and i support that. if you don't take an interest in the science of it, i'll make a note of that as well. thanks for your thoughts!

So do we all, only I choose life affirming actions for my loved ones rather than spinning the wheel of death.

originally posted by: jerich0
a reply to: fiverx313

The vaccine does not prevent you getting virus. Nor from spreading it. And while it might, in most cases (perhaps the 99.8% of those who would survive anyway?) prevent serious illness, what it actually does is allow asymptomatic people to meander around society, spreading it, should they be infectious.

So while someone feeling sick may stay at home and self quarantine, a vaccinated person will not. And you're worried about spreading it?

it does prevent you from getting the virus... 80%, sounding like based on current research. and it does seem like it's preventing a great deal of asymptomatic spread, again based on current research. those are both incredibly good things for slowing community spread, lessening the number of infections, lessening the number of hospitalizations, lessening the number of deaths. so yes, a vaccinated person may have a chance of spreading it, but it's still greatly reduced. and that's why it's a net benefit. that's just math, honestly.

a reply to: fiverx313

I agree in practice. But nothing on the table right now, prevents it spreading. Carriers will still spread it.

I guess it boils down to the individual - if you opt to feel safer, and are willing to accept experimental medical treatment, as long as you are willing to be diligent in ensuring you still wear a mask, maintain distance, and don't think you're immune, fair enough.

Personally, I'd prefer to know if I had it or not. Because the people I do care about, who may not be vaccinated, are also important to me, and I'd rather be safe than complacent.

a reply to: fiverx313

Who's math. Those who are advocating the vaccination, or those without vested interest who have said that there is no guarantee.

You get the coronavirus. You may or may not develop covid. but you are still a carrier.

originally posted by: BlueJacket
So do we all, only I choose life affirming actions for my loved ones rather than spinning the wheel of death.

i see you like that metaphor! but given the number of people who have died from covid, given the number of people who have died from being vaccinated, your odds are a lot better on the vaccine wheel of death than on the covid wheel of death. again, that's just math. but getting vaccinated is a highly personal decision that everyone has to make for themself, and i support anyone who chooses to skip it.