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originally posted by: whereislogic
a reply to: puzzled2
...
As the Eastern Virginia Medical School puts it:
Furthermore, it is likely that there will not be a single “magic bullet” to cure COVID-19. Rather, we should be using multiple drugs/interventions that have synergistic and overlapping biological effects that are safe, cheap and “readily” available.
Source: EVMS_Critical_Care_COVID-19_Protoco l.pdf
originally posted by: whereislogic
HCQ works great even at the latest stages of the disease during the cytokine storm.
High dose vitamin C works pretty good at this stage as well, but not as effective at dampening the storm.
originally posted by: whereislogic
Why put all your eggs in one basket with high dose vitamin C?
Which, btw, is also part of the EVMS protocol, but not the only component of their protocol, nor the main component in dampening the cytokine storm, which is how you safe lives when patients have reached that stage of the disease, by dampening the storm.
originally posted by: tanstaafl
originally posted by: whereislogic
HCQ works great even at the latest stages of the disease during the cytokine storm.
This totally contradicts the studies that have been done. The main reason they said it was ineffective was because it was used too late.
So, I guess you forgot to provide links to those studies that prove this from one of your approved sources.
And yes, I know I haven't done the same for C, because those studies don't exist - because there is no money in it.
originally posted by: whereislogic
...snip...
The EVMS also has high dose IV vitamin C in their protocol, which is a hospital protocol, that's where you can give patients this stuff IV, which allows you to use more.
Obviously that's not going to be part of any treatment used in the outpatient setting.
When I'm mentioning vitamin C as part of HCQ + quality care, Dr. Ban-style,
originally posted by: puzzled2
a reply to: whereislogic
...
It's not a matter of a playground "my sources are better than yours" verbal spat - it's about passing information that can be verified, understood and helpful to others.
originally posted by: tanstaafl
...
Obviously? I can get 100G IV treatments outpatient any time I want.
Yes, and they never use very much... 1 gram, maybe 5 grams, 10 at most.
2.Ascorbic acid (Vitamin C) 3g IV q 6 hourly for at least 7 days and/or until transferred out of ICU. Note caution with POC glucose testing (see below). [38-46]
1. Maggini S. A combination of high-dose vitamin C plus zinc for the common cold. Journal of International Medical Research 2012; 40:28-42.
2. Colunga Biancatelli RM, Berrill M, Catravas JD et al. Quercetin and Vitamin C: experimental therapy for the prevention and treatment of SARS-CoV-2 via synergistic action. medRxiv 2020.
3. Colunga Biancatelli RM, Berrill M, Marik PE. The antiviral properties of vitamin C. Expert Rev Anti Infect Ther 2020; 18:99-101.
4. Khaerunnisa S. Potential inhibitor of COVID-19 main protease (Mpro) from several medicinal plant compuns by molecular docking study. medRxiv 2020.
5. Yi L. Small molecules blocking the entry of severe respiratory syndrome coronavirus into host cells. J Virol 2020; 78:11334-39.
...
38. Marik PE, Khangoora V, Rivera R et al. Hydrocortisone, Vitamin C and Thiamine for the treatment of severe sepsis and septic shock: A retrospective before-after study. Chest 2017; 151:1229-38.
39. Barabutis N, Khangoora V, Marik PE et al. Hydrocortisone and Ascorbic Acid synergistically protect and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction. Chest 2017; 152:954-62.
40. Marik PE. Hydrocortisone, Ascorbic Acid and Thiamine (HAT therapy) for the treatment of sepsis. Focus on ascorbic acid. Nutrients 2018; 10:1762.
41. Marik PE. Vitamin C for the treatment of sepsis: The scientific rationale. Pharmacol Therapeut 2018; 189:63-70.
42. Cheng RZ. Can early and high-dose vitamin C prevent and treat coronavirus disease 2019 (COVID-19). Medicine in Drug Discovery 2020.
43. Wang Y, Lin H, Lin BW et al. Effects of different ascorbic acid doses on the mortality of critically ill patients: a meta-analysis. Ann Intensive Care 2019; 9:58.
44. Fowler AA, Truwit JD, Hite D et al. Vitamin C Infusion for TReatment In Sepsis-Induced Acute Lung Injury- CITRIS-ALI: A Randomized, Placebo Controlled Clinical Trial. JAMA 2018; 322:1261-70.
45. Boretti A, Banik BK. Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition 2020; 12:100190.
46. Iglesias J, Vassallo AV, Patel V et al. Outcomes of metabolic resuscitation using ascorbic acid, thiamine, and glucocorticoids in the early treatment of sepsis. Chest 2020.
BEIJING (Reuters) - Beijing banned high-risk people from leaving the Chinese capital and halted some transportation services on Tuesday to stop the spread of a fresh corona-virus outbreak to other cities and provinces.
Beijing had designated 22 neighborhoods as medium-risk areas as of Monday. Medium-risk areas are required to take stringent measures to block the potential entry of infection.
All high-risk people in Beijing, such as close contacts of confirmed cases, are not allowed to leave the city, state media reported on Tuesday, citing municipal officials.
All outbound taxi and car-hailing services have also been suspended. Some long-distance bus routes between Beijing and nearby Hebei and Shandong provinces were suspended.
The US race riots started around 16-20 days ago,
Beijing back in lockdown: Parts of the city are fenced off and new travel bans introduced to stop new 'extremely severe' coronavirus outbreak
China has put parts of Beijing back into lockdown and reimposed some travel restrictions in an attempt to contain a new coronavirus outbreak amid fears that a second wave is about to hit the country. Beijing's coronavirus situation is 'extremely severe', a city official warned Tuesday, as 27 new infections were reported in the Chinese capital from a cluster has sparked a huge trace-and-test programme. The coronavirus resurgence - believed to have started at the city's sprawling Xinfadi wholesale food market - has prompted alarm as China had largely brought its outbreak under control through mass testing and draconian lockdowns imposed earlier in the year.
originally posted by: whereislogic
originally posted by: tanstaafl
"I can get 100G IV treatments outpatient any time I want."
Good for you. When you are a highly contageous Covid-19 patient that is too sick to even get out of bed as Dr. Ban explains regarding his patients suffering from severe weakness/fatigue and not having eaten for quite a while, other considerations may apply though (such as a more continuous daily need for and dose of vitamin C, something you can't really go to the Doctor for every day).
In the hospital, you get an IV-tube on admittal, or whatever it's called in English.
"Yes, and they never use very much... 1 gram, maybe 5 grams, 10 at most."
They use (in the section "Dampening the Storm"):
"2.Ascorbic acid (Vitamin C) 3g IV q 6 hourly for at least 7 days and/or until transferred out of ICU. Note caution with POC glucose testing (see below). [38-46]"
That's 12g per day
and 84g total for 7 days. More than the "10 at most" you mentioned.
At least bother to take a quick peek, you won't sound so reluctant to look into anything that doesn't tickle your ears.
“For there will be a period of time when they will not put up with the wholesome* [Or “healthful; beneficial.”] teaching, but according to their own desires, they will surround themselves with teachers to have their ears tickled.* [Or “to tell them what they want to hear.”] They will turn away from listening to the truth and give attention to false stories.” (2 Timothy 4:3,4)
BREAKING: The Arizona health department reported 2,392 new coronavirus cases, a new daily high, and 25 additional deaths Tuesday morning.