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originally posted by: Charlyboy
a reply to: Pardon?
I would like to see those studies, can you cite them here please? I prefer to see the recent studies people talk about so I can read them myself. Did you read the paper about viral infection during pregnancy doubling the risk of autism due to auto immune responses? Could the same mechanism occur during vaccination in pregnancy? I clearly stated my beliefs, I would have no reason to falsify them because this thread was meant to be a conversation. I assume you didn't read the attached papers? Just read though the op quickly and left a fairly empty response.
Here is a short piece on herpes infection during pregnancy, possibly linked to Autism... Other viral infections are linked due to immune responses, it's not too hard to imagine a situation where an aggressive immune response to a vaccine may cause a similar situation.
The question is why???
www.sciencedaily.com...
originally posted by: Charlyboy
a reply to: Pardon?
I do understand what you are saying but the simple facts around 1 in 60 children born in the USA will be diagnosed with autism, you are accepting an unprovable narrative that autism rates have always been this way and there is no increase. Nobody can prove that the increase in autism is just diagnostic, the guess is that 60% of the increase is related to diagnosis, that still leaves 40%... Please read my op and my responses to others here, I clearly state that immune responses, specifically the type associated with viral infections may also lead to autism wether in utero or early childhood.
If you accept a narrative that there is no epidemic or if you prefer, a large increase in autism presentation then you quietly accept the situation without thought.
You will notice how quiet this thread is compared to most on this subject, and this I believe is in part due to the lack of emotive responses and the fact I am not polarised on this subject, I really am just looking at the science and biology.
Also I read the testimonies of parents which although anecdotal is a representation of the rapid onset of autistic behaviour seen in SOME cases. You cannot ignore this, if you do you are not looking at the evidence.
I am not being disingenuous, I am reading the literature (more than most people here I can assure you). I know vaccines have saved millions of lives and I would advocate people to vaccinate their children, that does not stop me seeing small risks associated with them.
Think of this, parents of a few children see a rapid decline in their Childs behaviour post vaccination, then a conspiracy driven by redacted claims whips up a heap of emotion causing a drop in vaccination rates, then we see a rise in preventable childhood diseases a dire situation, I think you will agree. The response is a flat out denial any child has suffered autism asa result of vaccination, yet a small number of parents continue to see this happen.
We end up polarised, fighting each other, no discussion just anger, ego and a situation where anti-vaccine groups deny the benefit of vaccines (truly horrifying in my mind) and the pro-vaccine group flatly denying to a small number of parents that what they saw happen to their children was just coincidence. This situation just feeds conspiracy and emotive behaviour without any real assessment of the biology or science.
The facts are this:
Vaccines have been used for decades, no problem.
Autism rates are increasing (regardless of what you believe).
A minority of parents see a change in their child shortly after vaccination (and I mean rapid onset after 24hrs, sometimes associated with seizures).
Immune response maybe responsible, indeed the pathology of autism suggests auto-immunity and inflammation as a cause in a high majority of cases.
Certain individuals are genetically predisposed.
I don't want to change anyones mind, I want people to look at the science, look at the biology and listen to the parents of the FEW children that experience rapid onset post infection/vaccination.
If we could identify those few at risk we can avert the declining vaccine rates, the suspicion of pharmaceutical companies and get back to protecting the children.
The latest estimate of autism prevalence — 1 in 68 — is up 30 percent from the 1 in 88 rate reported in 2008, and more than double the 1 in 150 rate in 2000. In fact, the trend has been steeply upward since the early 1990s, not only in the U.S. but globally, says Maureen Durkin, who heads the network site in Wisconsin.
1. Seafood: Maternal consumption of more than 2 servings per month was found to be a risk factor for ASD. This was true of 57% of the mothers of children with ASD, vs. 33% of the controls.
2. Oral Antibiotics: Due to a high incidence of ear infections, the children with ASD received much higher levels of oral antibiotics. This is important because 1) oral antibiotics destroy normal beneficial bacteria, can cause overgrowths of harmful bacteria and yeast, and 2) oral antibiotics greatly decrease the excretion of mercury, causing it to build up to higher levels.
3. Vaccines: Children with ASD were more likely to have an adverse reaction to vaccines, and those adverse reactions tended to be more severe. This could be due to the thimerosal in the vaccines.
4. Pica: The children with ASD were reported to be much more likely to have moderate to severe pica (30%) than the typical children (2%). Using a severity scale of 0-3, the difference was highly significant (0.9 vs. 0.04, p=0.00001). This consumption of non-food items, including sand, dirt, paper, and other objects, probably resulted in a significant increase in their exposure to toxic metals.
5. Dental Fillings: There was a trend (p=0.08) that the mothers of children with ASD were more likely to have had a mercury filling placed or removed during their pregnancy (7 cases vs. 1 case for the controls). This is relevant because our recent study has found that fillings release much more mercury when initially placed.
Several physical symptoms were found to be very common in ASD, with an extremely high statistical significance:
1. Gastrointestinal: 62% of the children with ASD had moderate or severe problems with chronic constipation and/or diarrhea, far more than the typical children (2%). The difference was highly statistically significant, 1.9 vs. 0.1, p=1 x 10-12. This may be partly due to the high usage of oral antibiotics, which can disrupt normal GI flora, which are important in promoting normal motility.
2. Sleep: 60% of the children with ASD were reported to have moderate or severe sleep problems, far more than the typical children (2%). Using a severity scale of 0-3, the difference was highly statistically significant, 1.8 vs. 0.2, p=1x10-13).
3. Sleep and gastrointestinal problems were moderately correlated, with a correlation coefficient of 0.31.
4. Muscle Tone: 30% of the children with ASD had moderate or severe problems with low muscle tone, far more than the typical children (on a scale of 0-3, 1.0 vs. 0.06, p=0.000000002).
5. Salivation/Drooling: 15% of the children with ASD had problems with salivation/drooling, much more than the typical children (p=0.0003). Salivation/drooling problems were moderately correlated with muscle tone problems (correlation coefficient = 0.47).
6. Ear infections: Children with ASD were reported to have had many more ear infections than typical children during their first three years of life (10.9 vs. 4.3, p=0.00006). Since almost all ear infections were treated with oral antibiotics, this resulted in much higher oral antibiotic use in children with ASD.
Regressive ASD was found to occur in 62% of the children with ASD, at an average age of 18 months. Those children met their developmental milestones (age of crawling, sitting, walking, and talking) at the normal time. In contrast, the children with non-regressive ASD were two months late in crawling and sitting, four months late in walking, and 17 months late in talking.
originally posted by: Charlyboy
a reply to: Pardon?
originally posted by: Charlyboy
a reply to: Pardon?
Your attitude is a little toxic, to suggest that I am a liar is also somewhat offensive. I have listed a number of articles and you suggest I use google scholar and could not cite them yourself. You are obviously completely opposed to ideas outside of your own beliefs on this topic and thats ok, but you have absolutely no right to suggest I am a liar.
If it is so difficult for you to have a civilised discussion I suggest you don't try.
originally posted by: Charlyboy
Again, and I must keep reiterating this point, I am not blaming vaccines for autism, I am saying that there is potentially a unique set of circumstances that creates an environment in susceptible children which when challenged by viral infection or vaccination triggers a rapid regression into autism. There are a number of parents who say their children change rapidly after reaction to a vaccine. Unfortunately this is ignored and we are told that autism just happens to manifest at the time of infection. If this was a biological process that was on going throughout development we would see a slow transition into the autistic spectrum not a rapid onset.
Also the idea that vaccines are responsible for all cases of Autism is absurd, I am really only interested in the relatively small number that are potentially vaccine mediated. If this is the case then it explains why parents see this transition shortly after vaccination and why we find ourselves in an atmosphere of fear and anxiety regarding vaccines. I personally would like these cases investigated to determine why these kids are susceptible so we could develop testing to mitigate these heartbreaking events.
No anecdotes to not hold water in science but we are not talking science we are talking medicine, science is responsible for the development of medical procedures, drugs and therapies. Medicine is responsible for the delivery and clinical observation post delivery of these therapies be physical, chemo active etc. Medicine is an art not a science, every single patient has different requirements due to their genetic disposition. I go to a doctor and say I ate a steak and got sick, he treats me for food poisoning although it is anecdotal the chances are its food poisoning, no scientific evidence.
I saw the child the day before he was vaccinated, he spiked a fever and bang, I saw him 2 days after and it was crushing. I have spent enough time in hospitals with my son who has a seizure disorder to understand how parents thoughts are often dismissed based purely belief systems from a pretty parrot fashion education system (yes the same education system I spent time in).
I am not blaming doctors, nurses or anyone for that matter, I am simply stating there is enough anecdotal evidence to warrant investigation. You simply cannot get scientific proof in the investigations are not undertaken.
originally posted by: Charlyboy
a reply to: Pardon?
No I just have testimonies from parents, medical science that describes immune-disorders maybe responsible and the pathway maybe triggered by viral infection. This as I clerkly stated may or may not be brought on in rare cases by vaccination in susceptible individuals.
Are there other environmental factors involved? Of course, is vaccination responsible for autism? No, may it trigger it in some instances, sure the whole point is to generate a strong immune response.
I am not talking about the 99% of cases I am asking the question is it possible and in my mind if the circumstances are right a vaccine or infection may trigger a cascade event.