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The rats who were fed the GM corn were given the MON810 corn as 30% of their diet. The control group was given the same amount of non-GMO corn.
In the group fed GM corn, the finger-like structures in the intestine known as villi that absorbs nutrients from food were clearly damaged. They were both distorted and flattened and some cells were even joined together.
The study includes images and shows photographs of the damage. There were also signs of inflammation around the areas of damage in the form of white blood cell infiltration. The mucosal glands were disturbed and blood vessels were congested. There was also an increased level of shedding of mucosal cells, higher rates of division of cells lining the mucosal glands and larger numbers of mucous secreting goblet cells.
The damage to the GM-fed rats was so obvious, that the researchers concluded, “consumption of GM-corn profoundly alters the jejunal histological [microscopic] structure”
Different morphometrical parameters were assessed. Specimens from GM-corn fed group showed different forms of structural changes.
°Focal destruction and loss of the villi leaving denuded mucosal surface alternating with stratified areas were observed, while some crypts appeared totally disrupted.
°Congested blood capillaries and focal infiltration with mononuclear cells were detected. Significant upregulation of PCNA expression, increase in number of goblet cells and a significant increase in both villous height and crypt depth were detected.
°Marked ultrastructural changes of some enterocytes with focal loss of the microvillous border were observed.
°Some enterocytes had vacuolated cytoplasm, swollen mitochondria with disrupted cristae and dilated rough endoplasmic reticulum (rER).
Some cells had dark irregular nuclei with abnormally clumped chromatin. It could be concluded that consumption of GM-corn profoundly alters the jejunal histological structure.
-Source
The jejunum has the typical histological pattern as the entire small intestine: mucosa, .... Structure of the duodenum, including the mucosa and muscular layers.
originally posted by: saadad
Like in 10 years we will know effects on humans. I hear that over there in USA you already eat GMO food without even knowing it.
originally posted by: DJW001
a reply to: 727Sky
How many of the ten rats fed GMOs actually showed intestinal damage?
originally posted by: DJW001
a reply to: 727Sky
On the other hand, if only one of then ten rats fed GMOs had intestinal problems, that would mean 10% showed adverse effects. This might look significant, but given the size of the sample, it would not be. The experimental design is flawed; they definitely need a larger sample and at least one more control group: rats fed a different proportion of GMOs in their diet to see if there is a threshold effect.
The rats who were fed the GM corn were given the MON810 corn as 30% of their diet. The control group was given the same amount of non-GMO corn.
In the first study, rats fed the MON810: Ajeeb YG for 45 and 91 days showed differences in organ and body weights and in blood biochemistry, compared with rats fed the non-GM Ajeeb parent variety grown side-by-side under the same conditions. The authors noted that the changes could indicate “potential adverse health/toxic effects”, which needed further investigation.[3]
In the second study, histopathological (microscopic) investigations by the same group of researchers found toxic effects in multiple organs in the rats fed the GM MON810: Ajeeb YG Bt corn for 91 days.
originally posted by: Vector99
From what I have read into this, it's not GMO's in general that are bad, it's the GMO's designed for pesticide purposes.
Any crop that is naturally poisonous to bugs is likely going to be poisonous to humans as well, poisons usually don't discriminate.
It could be concluded
Do I get this right?
So you start with : "if"
And you concluded with: "is" flawed.
Without reading it, and knowing anymore about it?
Bt proteins has been used in many organic farms for over 50 years as a microbial pest control agent (MCPA). Bt proteins are allowed in organic farming as a insecticide because Bt is a natural, non-pathogenic bacterium that is found naturally in the soil. Bt has also been found to be safe to all higher animals tested.