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Originally posted by superdude
This could be so wide spread it's scary. How many different species for crying out loud? Swine, sheep.........
How many of us are already infected?
Originally posted by justme1640
from the original lined article
Japan is the only country in Asia to have confirmed cases of BSE and, since October 2001, every cow slaughtered for consumption in the country has been screened for the disease.
Am I the only one confused that it took 3 years to tell us about the goat if the test can be done on each animal -- or are they testing each cow in Japan and 3 years from now might say "Oops that cow you ate 3 years ago had BSE. "
jm
Originally posted by superdude
Now how possible is it that this disease has already manifested itself in more animal types than we know? I for one think very possible. What is the gestation period for this presently?
link
A remaining loophole, Dr. Hansen said, is allowing rendered matter from cows to be fed to pigs and chickens and rendered pigs and chickens to be fed back to cows. In theory, that sequence could bring the disease full circle, back to cows.
...Do you really want me to answer that superdude?
www.emedicine.com...
“FMD frequency in the USA: incidence of new cases in adults diagnosed by angiography – 0.6%; diagnosed in autopsy – 1.1%.”
NOTE: Incidence means new cases found yearly, presented as a % of the total population.
Also see Puri, PMID: 10334397.
YEAR - DEATHS - TOTAL POP - EST ADULT POP (75%) - 1.1% ADULT POP: FMD incid in autopsy
1999 - 2,391,399 - 279,295,000 - 209,471,250 - 2,304,184
1998 - 2,337,256 - 276,115,000 - 207,086,250 - 2,277,949
1997 - 2,314,245 - 272,912,000 - 204,684,000 - 2,251,524
1996 - 2,314,690 - 269,667,000 - 202,250,250 - 2,224,750
1995 - 2,312,132 - 266,557,000 - 199,917,750 - 2,199,095
Source: Population: Census; Reported Deaths; World Health Organization.
As you can see, nearly 100% of the American population is infected with FMD by adulthood.
Originally posted by superdude
Do want you want with me, take me now, but leave my wife, and especially my kids alone.
Not just America, but the world, wake up! It's not nukes, it's not poor judgement in monetarily terms by the government. This could be the thing that takes us all out.
Originally posted by superdude
I have to ask the question, since the US government has blocked the testing, is it a man made "plague"?
Originally posted by superdude
Sofi, I just nominated you for way above.
Now are the prions actually what causes this disease? In what I've read, no one is sure.
“…this hypothesis would shed some light on other diseases not presently classified as prion diseases and in the process of ageing.”
* “Prion plaques: molecular tumors. A hypothesis on the etiopathogenesis of prion diseases.” Ossa JE, Machado G, Giraldo MA, McEwen JG. Facultad de Medicina, Universidad de Antioquia, Medellin, Colombia. Med Hypotheses. 1995 Feb;44(2):124-6. PMID: 7596306
“Cross-species infection with transmissible spongiform encephalopathy agents may lead to subclinical infection and to adaptation of the infection to new species.”
* “Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages.” Race R, Meade-White K, Raines A, Raymond GJ, Caughey B, Chesebro B. Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, 903 S. Fourth Street, Hamilton, MT 59840, USA. J Infect Dis. 2002 Dec 1;186 Suppl 2:S166-70. PMID: 12424693 QUOTE:
“Chronic Subclinical Prion Disease Induced by Low-Dose Inoculum” Received September 24, 2001; J Virol. 2002 March; 76 (5): 2510–2517 Alana M. Thackray,1 Michael A. Klein,2 Adriano Aguzzi,3 and Raymond Bujdoso www.pubmedcentral.nih.gov...
Ie., Understanding the diversity of prions. Nat Cell Biol. 2004 Apr;6(4):290-2. Aguzzi A. Adriano PMID: 15057242
Conformational variations in an infectious protein determine prion strain differences. Nature. 2004 Mar 18;428(6980):323-8. Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California-San Francisco, San Francisco, California 94143, USA. PMID: 15029196
Could it be in the milk supply?
Jeeezus...... Think about that for a moment. How many things are made with milk as an ingredient?
UCSF-led researchers have developed a highly sensitive, automated test for detecting prions (PREE-on) that they report significantly improves the accuracy and speed of detecting the various forms of the infectious agent, which causes a set of neurodegenerative diseases, in cattle, sheep, deer and elk.
...there is a large part of the abnormal prion protein that is protease sensitive, and that portion escapes detection by the standard technique. Thus, this traditional method underestimates the level of PrPSc in tissue.
“This finding indicates that previous attempts to quantify BSE and scrapie prions in milk or non-neural tissues, such as muscle, may have underestimated infectious titers by as much as a factor of 10,000, raising the possibility that prions could be present in these products in sufficient quantities to pose risk to humans,” says Safar.
“At present, we have no data on the frequency of sub-clinical prion infections in livestock,” says Safar. “Because most livestock destined for human consumption are slaughtered by two years of age, many animals may be infected but never show clinical signs of central nervous system dysfunction since incubation periods generally exceed three years.”
UCSF-LED TEAM REPORTS NEW TEST IMPROVES DETECTION OF PRIONS IN ANIMALS
www.sciencedaily.com...
Prion transmission in blood and urine: what are the implications for recombinant and urinary-derived gonadotrophins? Hum Reprod. 2002 Oct;17(10):2501-8. Reichl H, Balen A, Jansen CA. PMID: 12351519
Fly larvae and mites were exposed to brain-infected material and were readily able to transmit scrapie to hamsters. New lines of evidence have confirmed that adult flies are also able to express prion proteins. Several cell types found on the human skin, including keratinocytes, fibroblasts and lymphocytes, are susceptible to the abnormal infective isoform of the prion protein, which transforms the skin to produce a potential target for prion infection.
* Could ectoparasites act as vectors for prion diseases? Int J Dermatol. 2003 Jun;42(6):425-9. Lupi O. Center for Vaccine Development, University of Texas Medical Branch at Galveston, Galveston, TX, USA. PMID: 12786866
Now a real reach here - I've read that prions must be heated to almost 1000 degrees fareinheit - yes one thousand degrees, to render the useless. There is nothing that is heated to that degree. Is it possible that the belt, the gloves, or the shoes that we wear could transmit this as well?
quote:
Now a real reach here - I've read that prions must be heated to almost 1000 degrees fareinheit - yes one thousand degrees, to render the useless. There is nothing that is heated to that degree. Is it possible that the belt, the gloves, or the shoes that we wear could transmit this as well?
...I've read that it's possible....
Originally posted by superdude
So assuming that it is possible, this could be the "silent disease" that is the new plague? Speaking for myself. I am more than worried for humanity.......
Originally posted by Relentless
There is one ray of hope I came across in my research last year, but I'm sorry I cannot provide it at the moment. Apparently there was a study that indicated some people (I believe it was a decent percentage) do have a genetic resistance to developing the disease, even if exposed. If this is true, number one it can't wipe out mankind,
number two, there could be hope for developing a cure or prevention. Of course, someone has to first acknowledge the problem, and that is still a problem.
...The old "genetic susceptibility" and "genetic resistance" arguments are rooted in Eugenics - and lead to things like concentration camps.
Originally posted by sardion2000
Originally posted by soficrow
...The old "genetic susceptibility" and "genetic resistance" arguments are rooted in Eugenics - and lead to things like concentration camps.
.... So Genetics plays NO role whatsoever?
How does it lead to concentration camps hmm?
POLITICS WARPS SCIENCE TO SUIT ITS ADJENDA. Are all Genetists complicit? No I believe not but some usually are, that is no reason to vilify the entire field....
Originally posted by DrHoracid
... many researchers believe that insufficient evidence has been presented to prove this prion hypothesis conclusively.