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Pardon?
Firstly, beta-blockers aren't statins.
They are two very different drugs given for very different reasons.
Secondly, Polderman wasn't employed nor sponsored by pharma.
So if anything, blame the doctors for prescribing these in error as a result of bad research rather than the drugs themselves.
Beta-blockers are among the most commonly used drugs for controlling high blood pressure and improving blood flow to the heart. They slow the heart rate, lower blood pressure, and decrease the amount of work the heart must do. By lowering the heart's oxygen needs, beta-blockers may help prevent or relieve poor blood flow.
. . .
Statins are the most frequently prescribed type of cholesterol-lowering drugs. They block a key liver enzyme involved in cholesterol production. This helps restrict the amount of cholesterol that can be deposited into the blood. It also increases the amount of LDL, or "bad," cholesterol that can be removed from the blood. Studies have shown that people who use statins have a reduced risk for heart attack, stroke, chest pain, and death from a heart-related condition.
"They note that more than half of the lives lost—potentially more than 400,000—may 'have occurred after the research was discredited,'
marg6043
reply to post by bobs_uruncle
I read somewhere a long time ago that if you are put in three or more medicines and you are not in any imminent danger when it comes to your health you should question the doctor about it and if you get side effects from any medicine that you feel uncomfortable and takes away your quality of life, that medication is not worth taking.
I live by it, most doctors only prescribe drugs because it means income, but is also doctors out there that are medical practitioners but also practice naturopathy, they can find a combination of drugs and natural alternatives that can decrease the need for medical drugs that means less side effects.
Skywatcher2011
reply to post by beckybecky
From the link:
"They note that more than half of the lives lost—potentially more than 400,000—may 'have occurred after the research was discredited,'
I still would like to know the mean age of those that died from malpractice of medication treatments. To me, this means that doctors are pushing drugs at patients faster than they can understand what side effects are produced by consumed medications...moreover, we don't know from the research whether or not other medications were taken by patients which exacerbated the patient heart conditions when taken with these beta blockers.
Some information has not been presented to us to make a clear conclusion big pharma is to blame. I think doctors and nurses are to blame for this.
In an interview, Francis said that there is no way to reliably assess the true extent of the possible damage, either in the UK or elsewhere. The estimate of 10,000 deaths is based on the limited available data.
Sanjay Kaul said that he generally agreed with the conclusions of the Heart paper that the evidence does not support strong recommendations for perioperative beta blockade, but he said that “the mortality evidence against beta blockade is not robust.”
Some defenders of perioperative beta-blockade have argued that although initiating beta-blockers on the same day as surgery may be dangerous, a slow and gradual introduction of the drugs for as long as 30 days before surgery may be beneficial. However, according to Francis, this strategy has never been tested in a clinical trial outside of the DECREASE family.
Bluesma
Don Poldermans was a respected physician before this scandal.
To be precise, the charges were on one study (the one which is relevant here). The situation isn't as clear cut as it sounds here.
The "whistle blower" himself is the source of part of the charges. He as working on the trial for Poldermans, and did things like not getting consent from patients before enrolling them in the trials. This was not known by Poldermans, but legally he is held responsible for that. more on Poldermans scandal
-My personal reflection is- if you can get yourself working on a study, and then do some unethical things on it sneakily, then blow the whistle on that later, getting the responsible one you tricked blamed, what an easy way to destroy someone!
Not saying I believe this man to be innocent, just saying it isn't that clear. He was a researcher with a clean past and a huge amount of research behind him before that study.
Also, the media loves to use big numbers in mortality rates- but the reality is, they are calculated in ways which cannot stand reliably. There are not 800,000 individuals known to be dead and suspected of that being caused by this treatment. Another study showed a potential percentage of deaths that could be influenced by using beta blockers to prepare for a cardiac surgery, in a small sample, and then that is applied to the larger numbers of people who have had this treatment for surgery over the years. No individual cases are examined.
[url]http://www.forbes.com/sites/larryhusten/2013/07/31/european-heart-guidelines-based-on-disgraced-research-may-have-caused-thousands-of-deaths/[/ur l]
In an interview, Francis said that there is no way to reliably assess the true extent of the possible damage, either in the UK or elsewhere. The estimate of 10,000 deaths is based on the limited available data.
Sanjay Kaul said that he generally agreed with the conclusions of the Heart paper that the evidence does not support strong recommendations for perioperative beta blockade, but he said that “the mortality evidence against beta blockade is not robust.”
The subject is complex. For example-
Some defenders of perioperative beta-blockade have argued that although initiating beta-blockers on the same day as surgery may be dangerous, a slow and gradual introduction of the drugs for as long as 30 days before surgery may be beneficial. However, according to Francis, this strategy has never been tested in a clinical trial outside of the DECREASE family.
(DECREASE was the study in question that Poldermans did.)
beckybecky
How many people does it take before it becomes wrong?
A thousand? Fifty thousand?
A million?
How many people DOES IT TAKE?