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A long-awaited update to cholesterol treatment recommendations was issued Tuesday, and it could lead to a doubling of the number of Americans taking cholesterol-lowering statin drugs from 36 million to 72 million—about 30 percent of US adults.
The new treatment guideline lowers the threshold for those deemed to be at significant risk for having a heart attack or stroke and encourages doctors to treat these patients with statins to prevent cardiovascular disease—even if their cholesterol levels are not elevated. ...
In particular, the guideline urges doctors to use a new assessment tool to determine a patient’s risk of having a heart attack or stroke, one that has not been tested in studies, and to prescribe more potent, higher-dose statins as a first-line treatment while abandoning other cholesterol-lowering drugs such as Zetia (ezetimibe) and Lopid (gemfibrozil) ..
About 50 percent of white men and 60 percent of African-American men in their 50s would now fall in the high-risk category of people who should be treated with statins, as would all men by the time they reach age 70, according to Dr. Roger Blumenthal, director of preventive cardiology at Johns Hopkins Hospital, who reviewed the guidelines. The vast majority of African-American women in their 60s would too, along with one-third of white women.
The guidelines were issued Tuesday by the American Heart Association and American College of Cardiology. Some doctors not involved in writing the guidance worry that it will be tough to understand....
Roughly half the cholesterol panel members have financial ties to makers of heart drugs, but panel leaders said no one with industry connections could vote on the recommendations.
"It is practically impossible to find a large group of outside experts in the field who have no relationships to industry," said Dr. George Mensah of the heart institute. He called the guidelines "a very important step forward" based on solid evidence, and said the public should trust them.
Statins aren’t entirely without risks. Muscle soreness and fatigue are the most common side effects of taking the drugs. Other, less likely, consequences include liver damage, digestive problems, rashes or flushing, elevated blood sugar or Type 2 diabetes, and memory loss. In addition, once a person begins taking statins, he is likely to remain on them for the rest of his life.
Lloyd-Jones, the Northwestern doctor who helped develop the new guidelines, said there’s overwhelming consensus in the medical world that statins are effective and safe. “If these were unsafe drugs, we certainly wouldn’t have put the threshold where we did,” he said.
Raxoxane
There is a saying,don't scratch where it don't itch.
Raxoxane
reply to post by FlyersFan
.."Even if their cholestrol levels are not elevated"..
There is a saying,don't scratch where it don't itch.That would certainly apply here.In those without elevated cholesterol levels,what would be the point of taking these statins? Seems completely unnnecessary.The less of chemicals folks put into their bodies the better.edit on 13-11-2013 by Raxoxane because: (no reason given)
DJW001
just ignore them and cut down on the bacon and eggs in the morning.
A recent British study eight weeks ago of more than 2 million patients found that those using statins were significantly more likely to suffer cataracts.The five-year study found that for every 10,000 patients on statins, up to 307 more had cataracts than non-statin users.
FDA New Warning Label for Statins -
Following an internal meeting between the FDA's Office of Surveillance and Epidemiology and Office of New Drugs, the Agency announced it would be requiring additional warning labels for statin drugs. Among them are warnings that statins may increase the risk of:
Liver damage
Memory loss and confusion
Type 2 diabetes
Muscle weakness (for certain statins)
Ironically, while reducing your risk of cardiovascular events and heart disease is the primary motivation for prescribing statins, these drugs can actually increase your risk of heart disease because they deplete your body of Coenzyme Q10 (CoQ10), which can lead to heart failure. Statins lower your CoQ10 levels by blocking the pathway involved in cholesterol production -- the same pathway by which Q10 is produced. Statins also reduce the blood cholesterol that transports CoQ10 and other fat-soluble antioxidants..
Statins are associated with a few rare, but potentially serious, side effects including:
- Myositis, inflammation of the muscles. The risk of muscle injury increases when certain other medications are taken with statin use. For example, if you take a combination of a statin and a fibrate -- another cholesterol-reducing drug -- the risk of muscle damage increases greatly compared to someone who takes a statin alone.
- Elevated levels of CPK, or creatine kinase, a muscle enzyme that when elevated, can cause muscle pain, mild inflammation, and muscle weakness. This condition, though uncommon, can take a long time to resolve.
- Rhabdomyolysis, extreme muscle inflammation and damage. With this condition, muscles all over the body become painful and weak. The severely damaged muscles release proteins into the blood that collect in the kidneys. The kidneys can become damaged trying to eliminate a large amount of muscle breakdown caused by statin use. This can ultimately lead to kidney failure or even death. Fortunately, rhabdomyolysis is extremely rare. It occurs in less than one in 10,000 people taking statins.
TDawgRex
Everybody I know who are taking Statins have all complained of weakness, fuzzy memory and being dizzy with no notice.
CJCrawley
The science behind statins is sound - there's a rock solid link between elevated cholesterol levels and atherosclerosis.
Glinda
I can't/won't bring myself to make even an appointment for a yearly check up (and it's been a number of years!). I don't want pulled into the vortex of "doctoring" and medicating. There. I admitted it.
FlyersFan
TDawgRex
Everybody I know who are taking Statins have all complained of weakness, fuzzy memory and being dizzy with no notice.
I know a people on them, or were on them. All except one of them have said they have fuzzy brains now and/or physical issues like severe muscle cramps, etc etc. The brain fog is what is most alarming to me.