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All a carburetor can do is meter and atomize fuel in correct proportion to air.
Any further increases have to come from increasing the thermal efficiency of the engine itself (such as raising compression) or reducing rolling friction. And this last is why a diesel locomotive with steel wheels will go ten times as far on a gallon of fuel as a diesel truck of the same weight with rubber tires.
For Pogue�or any similar carburetor�to go 100 mpg on a gallon of fuel on a vehicle normally going 20 mpg, the air/fuel ratio would have to be in the neighborhood of 75 to 1 or better.
Any second-year college chemistry student knows that.