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"I am a spiritual being, the same as you, primarily. Then I'm a human being and this part of the human being is the body, which has a condition."
Botha was born in Cape Town, South Africa and still lives there. He was diagnosed with progeria around the age of 4 years. He had no formal training in art beyond high school courses, but became a full-time painter after graduation, doing commissioned works.
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In January 2010 he hosted the first exhibit of "Who Am I? ...Transgressions", a photo collaboration with Gordon Clark, at the Joao Ferreira Gallery in Cape Town.[8] Botha said of the exhibition, "I am a spiritual being, the same as you, primarily. Then I'm a human being and this part of the human being is the body, which has a condition."