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A nine-year-old girl in London and a man and a girl in West Yorkshire have all died after contracting swine flu.
The child from south London had "serious underlying health problems," as did the other two victims, who are thought to be from Dewsbury.
A 19-year-old man has died after contracting swine flu in London, health authorities in the capital have said.
The man, from south London, had serious underlying health problems and was in Lewisham Hospital. Tests undertaken after his death showed he had the flu.
A girl, thought to be six years old, has died at Birmingham Children's Hospital after contracting swine flu.
NHS West Midlands said the girl, who had other serious health problems, died on Friday evening. It is not known if flu contributed to her death.
Man and girl dead in Dewsbury after catching swine flu
Two people in Dewsbury have died after catching swine flue
Published Date: 06 July 2009
A GIRL of nine and a man, believed to be a teacher, have died in Dewsbury after catching swine flu, it was confirmed today. The girl died on Thursday and the man on Sunday.
The deaths in the West Yorkshire town were confirmed today by officials from NHS Kirklees.
The girl who died, Asmaa Hussain, nine, from Scout Hill, Dewsbury, had epilepsy.
It is the second tragedy to hit the family. Her father died two months ago.
The man who died was 42 and lived in the Savile Town area of Dewsbury. He was from a South Asian background. It is believed he suffered from lung and kidney problems.
It is believed that the man was a teacher at the Institute of Islamic Education, a private boarding school in Savile Town, Dewsbury, although NHS Kirklees officials would not comment on this.
The coroner has been informed of both deaths.
The Yorkshire Post understands that there will not be an inquest into the man's death as the coroner has decided that he died from natural causes, although the exact cause of his death has not been publicly released.
A post mortem examination on the girl is expected to be conducted later this week.
A spokesman for the Department of Health said that if the deaths are confirmed as swine flu they will be the sixth and seventh confirmed deaths in the UK.
A spokesperson for NHS Kirklees said: "We can confirm that a child from the Kirklees area, who had swine flu, has died. The child also had serious underlying health issues.
"At this stage, we have no confirmation whether or not swine flu was the cause of death."
/lzyo59
On July the second a total of 140 swine flu cases have now been diagnosed in the Yorkshire and Humber region.
It is believed that the man was a teacher at the Institute of Islamic Education, a private boarding school in Savile Town, Dewsbury, although NHS Kirklees officials would not comment on this.
Kirklees swine flu school stays closed
Jul 2 2009 By Huddersfield Examiner
A DEWSBURY school remained closed today after three pupils were diagnosed with swine flu.
The boys – all pupils at the Institute of Islamic Education College – are the first in Kirklees to be treated for the virus.
The teenagers are said to be responding well to antiviral drugs at the private Savile Town boarding school.
They are not thought to have recently travelled abroad.
Today, it emerged more pupils and staff at the college were showing flu-like symptoms leading to a decision to close the school for seven days.
They have also been offered antiviral treatment and are being monitored by health officials.
The all-boy independent school is home to 214 boarding pupils and around 100 day students aged between 12 and 19.
All UK-based pupils have been sent home while those from overseas are continuing to board at the school.
Dr Judith Hooper, director of public health for NHS Kirklees said: "We can confirm that three cases of swine flu have been confirmed in Kirklees.
"The individuals concerned are pupils at the Institute of Islamic Education College, Dewsbury, and are being treated at Dewsbury with antiviral medicine at the Institute.
"They are responding well to treatment.