FDA approves human embryonic stem cell study

FDA approves human embryonic stem cell study

www.cnn.com

Federal regulators have cleared the way for the first human trials of human embryonic stem-cell research, authorizing researchers to test whether the cells are safe to use in spinal injury patients, the company behind the trials announced Friday.

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One can only imagine what implications this has on the future of diseases and injuries. Those confined to wheelchairs with spinal injuries may again have the ability to walk. This is going to be interesting to see where it goes!



[edit on 23-1-2009 by branh03]

[edit on 23-1-2009 by branh03]

Could open up a pandora's box, this.

I for one am happy at the news. Thanks for posting it!

Valuable scientific research can now take place and I hope it opens the doors to other treatments too.

The 'ultimate' is to use the stem cells to stop or repair the effects of aging. Dr Aubrey De Grey is a pioneer in that field. I'd recommend researching into what he does.

Finally the advancement of medical technology can continue!! Yet again a religious barrier has been broken through. Look forward to the advancement of our species.

FOOLS

Forbes Magazine provided additional confirmation that adult stem cell research is far more successful that embryonic stem cell experimentation. They quoted an article printed in the Wall Street Journal Europe by Richard Miniter.

"Of the 15 US biotech companies solely devoted to developing cures using stem cells, only two focus on embryos. Embryo stem cell research is at the drawing-board stage - not for lack of funds but for lack of promising research to finance. Venture capitalists have no agenda beyond making money; if they see embryo projects that are likely to bear fruit over the next five to seven years - the usual VC time horizon - they will fund them. That the market is speaking so loudly against embryo stem cell research probably explains why embryo researchers are so eager to reverse the ban on government funding."

To date, current research on embryonic stem cells has resulted in no promising results. Ironically, a leading pro-ESCR advocate is the Juvenile Diabetes Foundation, but ESCR research has failed in fighting this disease.

Past supporters of this controversial research are now speaking out about the false hype surrounding the results. The San Francisco Chronicle recently reported that doubters are coming out of the woodwork. Paul Billings, who studied stem cells' effects and co-founded a stem cell bank, said that hopes for major new medical treatments based on embryonic stem cells are "very remote". "The problems are so complex that we're not likely to be able to tackle them with the stem cell gambit in the foreseeable future."

Researchers in China met with a disastrous result. Fetal tissue injected into a patient's brain produced temporary improvement, but within two years the patient developed a brain tumor and died. An autopsy revealed that the fetal cells had taken root, but had then metamorphed into other types of human tissue - hair, skin and bone. These grew into the tumor, which killed the patient.

A devastating result occurred at Columbia University's College of Physicians and Surgeons, and was published in the New England Journal of Medicine.

In some of the patients, the implanted embryonic cells apparently grew too well, churning out so much of a chemical that controls movement that they writhed and jerked uncontrollably. Dr. Paul E. Greene called the uncontrollable movements developed by some patients as "absolutely devastating." He said, "They chew constantly, their fingers go up and down, their writs flex and distend. It's a real nightmare. And we can't selectively turn it off. No more fetal transplants. We are absolutely and adamantly convinced that this should be considered for research only."

Diane Irving, Ph.D., a former professor of biology at Georgetown University and former biochemist with the National Cancer Institute, said, "I have argued that adult stem cells are better because they are closer to the stage of differentiation than embryonic or fetal cells - therefore they do not have as long a distance to travel differentiation-wise as the younger cells. Therefore there is far less of a chance for genetic errors to be accumulated in the implanted cells and less side effects for the patient to deal with."

In stark contrast to the failures of embryonic stem cell research, the future looks very promising for treatment with adult stem cells.

In stark contrast to the failures of embryonic stem cell research, the future looks very promising for treatment with adult stem cells.

The following are examples of research breakthroughs with adult stem cells. Please note that this list is only a sampling.

* Researchers at Harvard Medical School say adult stem cells may eliminate the need for embryonic ones. The researchers experienced a permanent reversal of Type 1 diabetes in mice by killing the cells responsible for the diabetes. The animals' adult stem cells took over and regenerated missing cells needed to produce insulin and eliminate the disease. The results hold promise for rheumatoid arthritis, multiple sclerosis, lupus and more than 50 other ailments.

* At the University of Texas MD Anderson Cancer Center in Houston, a man with a rare, potentially fatal skin disorder that was so severe that he could no longer eat, is now symptom-free after receiving a transplant of his own adult stem cells.

* Doctors at Northwestern Memorial Hospital in Chicago extracted the adult stem cells from the blood of two Crohn's patients and successfully used them to rebuild their faulty immune systems.

* Dr. Edward Holland of the Northern Kentucky Eye Laser Center in the greater Cincinnati metropolitan area, is using adult stem cell transplants as part of a treatment to dramatically improve the eyesight of his patients.

* New research in the UK on rats indicates that transplants of adult stem cells can help stroke victims regain movement, senses and understanding. They also show that the adult cells were more effective than cells from aborted babies.

* The Albert Einstein College of Medicine in New York came to similar conclusions.

* A study by the Institute for Stem Cell Research in Milan, Italy showed that certain cells from the brains of adult rats can be used to generate muscular tissue.

* Researchers at the University of South Florida in Tampa have found that adult stem cells from the umbilical cord blood may be able to help repair damaged brain tissue after a stroke.

* Scientists at the University of Medicine and Dentistry of NJ have found that bone marrow cells may be converted into replacement nerve cells, able to treat brain and nerve injuries. Dr. Ira Black and his team were able to convert 80% of the bone marrow cells into nerve cells.

Too bad big pharma will control prices on any benefits that may come out this thus making it affordable to only the wealthy.