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In a coc aine vaccine, for example, coc aine molecules are attached to harmful bacteria, which is then introduced into the bloodstream.
The body makes antibodies for the coc aine, and those antibodies prevent subsequent coc aine molecules that enter the body from reaching the brain, neutralizing the drug's effect.
Users of the harmful drugs would eventually learn there was no longer a reward for taking them, and they would stop using them, said Thomas Kosten of the Baylor College of Medicine in Houston.
For example, because the vaccines don't remove a person's addiction, people will take more of the drug in an attempt to get high.
If cigarette smokers start to smoke more because of a vaccine, the increased level of toxins could have adverse effects, Kosten said.
Another problem: Many people have multiple addictions, and the reduction of one could lead to the increased use of another drug.