IT MAYBE ONE OF THESE TWO CONDITIONS .
Anencephaly
Anencephaly is a cephalic disorder that results from a neural tube defect that occurs when the cephalic (head) end of the neural tube fails to close,
usually between the 23rd and 26th day of pregnancy, resulting in the absence of a major portion of the brain, skull, and scalp. Infants with this
disorder are born without a forebrain, the largest part of the brain consisting mainly of the cerebral hemispheres (which include the isocortex, which
is responsible for higher level cognition, i.e., thinking). The remaining brain tissue is often exposed - not covered by bone or skin.
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Harlequin type ichthyosis
Harlequin-type ichthyosis (also harlequin ichthyosis, ichthyosis congenita, or keratosis diffusa fetalis), a skin disease, is the most severe form of
congenital ichthyosis, characterized by a thickening of the keratin layer in fetal human skin. In sufferers of the disease, the skin contains massive,
diamond-shaped scales, and tends to give off a reddish color. In addition, the eyes, ears, mouth, and other appendages may be abnormally contracted.
The scaly keratin greatly limits the child's movement. Because the skin is cracked where normal skin would fold, it is easily pregnable by bacteria
and other contaminants, resulting in serious risk of fatal infection.
Sufferers are known as harlequin fetuses, harlequin babies, or harlequins.
The harlequin-type designation comes from both the baby's apparent facial expression and the diamond-shape of the scales (resembling the costume of
Arlecchino), which are caused by severe hyperkeratosis. The disease can be diagnosed in the uterus by way of fetal skin biopsy or by morphologic
analysis of amniotic fluid cells obtained by amniocentesis. In addition, doctors can now usually recognize common features of the disease through
ultrasound, and follow up with 3D ultrasound can diagnose the condition
Man Survives Rare Skin-Shedding Disease
Harlequin Ichthyosis Usually Fatal At Birth
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