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Since new kinds of creatures tend to appear when a new habitat does, that's when human ancestors must have lost their body hair for good—and made up for it with clothing that, besides keeping them warm, provided a home for the newly evolved louse.
By analyzing the DNA of today's humans as well as chimps and other species (even lice), scientists are zeroing in on turning points in evolution, such as when and how language and speech developed, and when our ancestors left Africa. DNA can even reveal how many pilgrims made that trek. At the new Hall of Human Origins at the American Museum of Natural History in New York, DNA gets equal billing with fossils. And by comparing the impressions that brains left on the inside of skulls, "paleoneurology" is documenting when structures that power the human mind arose, shedding light on how our ancestors lived and thought. Whether or not you believe the hand of God was guiding these changes, the discoveries are overturning longstanding ideas about how we became human.
Our species' travels through time proceeded in fits and starts, with long periods when "nothing much happened," punctuated by bursts of dizzying change, says paleontologist Ian Tattersall, co-curator of the American Museum's new hall.
Human DNA and chimp DNA differ by no more than 1.2 percent, and DNA changes at a fairly regular rate. That lets scientists use this rate to calibrate a "molecular clock" whose tick-tocks measure how long ago a genetic change occurred. The fact that the DNA of living chimps and humans differ by about 35 million chemical "letters," for instance, implies that the two lineages split 5 million to 6 million years ago.
Now the contentious part. In 2001, a team digging in Chad unearthed what it claimed was the oldest fossil of an ancestor of humans but not chimps. If so, it must have lived after the two lineages split. Trouble was, Sahelanthropus tchadensis (nicknamed Toumai, the local word for "child") lived close to 7 million years ago. The genetic data, pointing to a human-chimp split at least 1 million years later, suggest that Toumai is not the ur-hominid—the first creature ancestral only to human and not our chimp cousins—after all.
Last summer scientists discovered a gene called HAR1 (for human accelerated region) that is present in animals from chickens to chimps to people. It had changed in only two of its 118 chemical "letters" from 310 million years ago (when the lineages of chickens and chimps split) to 5 million years ago. But 18 letters changed in the (relative) blink of an eye since the human lineage split from chimps', Katherine Pollard of the University of California, Davis, and colleagues reported. That high rate of change is a sign of a gene whose evolution keeps conferring advantages on those who carry it, perhaps starting with Australopithecus. The brain, more than any other organ, may have reaped those genetic advantages. HAR1 reaches a peak of activity from the seventh to ninth week of gestation in humans, apparently spurring brain growth. And it is plentiful in cells that create the six layers of neurons in the human cortex. "HAR1 is present in neurons that play a role in the geometry and layout of the cortex," says Pollard. It likely helped the cortexes of our ancestors develop the elaborate folds characteristic of a complex brain.
And it helps explain why Lucy's kind were the way they were. Afarensis women and men stood three to five feet tall and weighed 60 to 100 pounds. They had small teeth good for fruits and nuts, but not meat. (The available prey was enough to make one a confirmed vegetarian: hyenas the size of bears, saber-toothed cats and other mega-reptiles and raptors.) That suggests that early humans were more often prey than predators, says anthropologist Robert Sussman of Washington University, coauthor of the 2005 book "Man the Hunted." The evidence is as stark as the many fossil skulls containing holes made by big cats and talon marks from raptors.
Both genetics and paleoneurology back that up. A hormone called oxytocin, best-known for inducing labor and lactation in women, also operates in the brain (of both sexes). There, it promotes trust during interactions with other people, and thus the cooperative behavior that lets groups of people live together for the common good. By comparing the chimp genome with the human, scientists infer that oxytocin existed in the ancestor of both. But it has undergone changes since then, perhaps in how strongly the brain responds to it and in how much is produced. The research is still underway, but one possibility is that the changes occurred around the time our ancestors settled into a system based on enduring bonds between men and women, about 1.7 million years ago.
Asymmetry is a mark of increasing specialization and therefore complex cognitive ability. Erectus used it to, among other things, discover and tame fire. What they did not use it for is technology. Tools found with the Dmanisi fossils include cutting flakes, rock "cores" from which flakes were made and a chopper, all primitive even for their time. "The old idea that you needed a master's degree in stone tools to leave Africa is crazy," says Bernard Wood.
Peter Underhill, a molecular anthropologist at Stanford University, tracked 160 such changes in the Y's of 1,062 men from 21 populations across the world. Applying the molecular-clock technique, he concludes that the most recent common ancestor of all men alive today lived 89,000 years ago in Africa. The first modern humans—and therefore, unlike the earlier wave of Homo erectus into Asia a million years ago, the ancestors of everyone today—departed Africa about 66,000 years ago.
The first, called FOXP2, plays a role in human speech and language, but it must do something else in other species, because the decidedly nonverbal mouse has a version of it. Using the standard molecular-clock tactic, Svante Paabo and colleagues at the Max Planck Institute estimate that the human version of FOXP2 appeared less than 200,000 years ago—about when anatomically modern humans stepped onto the world stage—and maybe as recently as 50,000. If so, then it is only humans as modern as those in the last diaspora out of Africa who developed advanced, spoken language. Another gene with interesting timing is microcephalin, which affects brain size. It carries a time stamp of 37,000 years ago, again when symbolic thinking was taking hold in our most recent ancestors. The third, called ASPM and also involved in brain size, clocks in at 5,800 years. That was just before people established the first cities in the Near East and is well after Homo sapiens attained their modern form. It therefore suggests that we are still evolving.