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BUENOS AIRES : Millions of diabetics worldwide could put insulin injections behind them if a stem cell treatment that Argentine physicians have successfully used to reverse the disease confirms promising early results.
The treatment, in which stem cells are injected into the pancreas, does not involve risks of rejection, requires no prolonged inpatient treatment, and any physician trained in and skilled with catheterization could perform it, cardiologist Roberto Fernandez Vina told AFP.
Fernandez Vina leads the team that successfully carried out the first implant of its kind January 3 on an insulin-dependent diabetic patient at San Nicolas Hospital in the town of San Nicolas, north of Buenos Aires.
The 42-year-old man, who had been insulin dependent since the age of 25, so far has seen his glucose levels return to normal with no need for medication.
People with diabetes have a shortage in the pancreas of so-called beta cells, which have the task of producing insulin, with which the body regulates glucose levels in the blood.
Introducing "copy-making" cells in the pancreas generates beta cell production, thereby increasing the production of insulin needed to balance the patient's glucose level.
US scientists believe they have found a way to use brain stem cells to "cure" diabetes. Although the work is not yet ready to be tested on human patients, results in animals have been promising, say the Stanford University researchers.
Transplants could ultimately remove the need for daily insulin injections
It may soon be possible to halt -- or even cure -- type 1 diabetes. The unexpected key: Spleen cells.
The surprising findings come from Denise Faustman, MD, PhD, and her team at Massachusetts General Hospital's Immunobiology Laboratory. The researchers hit on a way to regenerate the insulin-making islets in the pancreas that function in response to blood sugars.
Why Did the JDRF Try to Discredit Cure Research?
Denise Faustman, MD, reversed type 1 in mice. When she approached the JDRF with a request to replicate the research in humans, the reviewers took a pass.
Merrill Goozner, director of the Integrity in Science Project for The Center for Science in the Public Interest, is disturbed by the JDRF going to these lengths to discredit Faustman.
“It is shocking to see that scientists, rather than evaluating something on its merits, would spend so much time attacking the messenger. You have to wonder, what is their real motivation? You would think that scientists connected with the JDRF would be pursuing every effective cure, not attacking approaches that rival their own.”
A 61-year-old man has become the first person in the UK to be cured of type 1 diabetes thanks to a groundbreaking cell transplant technique. Richard Lane is now free of daily insulin injections.
Professor Stephanie Amiel, who leads the diabetes team at King's College Hospital, said: "The implications for the future are enormous. "Eventually this could mean the end of insulin dependence for all type 1 diabetes sufferers."
Originally posted by XanaX
Future Diabetes Treatment: Spleen Cells
It may soon be possible to halt -- or even cure -- type 1 diabetes. The unexpected key: Spleen cells.
The surprising findings come from Denise Faustman, MD, PhD, and her team at Massachusetts General Hospital's Immunobiology Laboratory. The researchers hit on a way to regenerate the insulin-making islets in the pancreas that function in response to blood sugars.
the rest of the article: my.webmd.com...
Again, the pancreas comes into play! Faustman's T-cell retraining technique may help other diseases besides type 1 diabetes. Misguided T cells also are at the heart of other autoimmune diseases such as lupus and Crohn's disease.
Kathryn Hentz is president of the Iacocca Foundation, which funds innovative approaches to a diabetes cure. "It may someday be possible to apply [Faustman's] technique in reversing rheumatoid arthritis, multiple sclerosis, and lupus," Hentz says in a news release.
edit to add: www.hon.ch...
"Massachusetts researchers say they have cured type 1 diabetes in mice."
[edit on 15-10-2005 by XanaX]
Originally posted by Lysergic
And can anyone tell me WHY we don't allow stemcel research here in the good ol' USA?
Anyone?
Originally posted by Lysergic
And can anyone tell me WHY we don't allow stemcel research here in the good ol' USA?
Anyone?
it's worth 5 ernesto plucks!
We should be at the forefront of this, but NO (screams bloody murder)
Adult vs. embryonic stem cell success now quoted at 70 to 0
The group that brought you the 65 successes number we used to see all the time in stories about adult vs. embryonic stem cells has now increased their success number to 70.
Embyronic stem cells, on the other hand, have yet to prove themselves. While this is not surprising considering the limitations on this form of stem cell research, many use the "failure" factor to discredit embryonic stem cell research.