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By altering a very specific step in gene regulation, this compound essentially re-educates cancer cells into normal cells that die as scheduled.
Through additional experimentation, the team established that apigenin had relationships with proteins that have three specific functions. Among the most important was a protein called hnRNPA2.
This protein influences the activity of messenger RNA, or mRNA, which contains the instructions needed to produce a specific protein. The production of mRNA results from the splicing, or modification, of RNA that occurs as part of gene activation. The nature of the splice ultimately influences which protein instructions the mRNA contains.
Doseff noted that abnormal splicing is the culprit in an estimated 80 percent of all cancers. In cancer cells, two types of splicing occur when only one would take place in a normal cell -- a trick on the cancer cells' part to keep them alive and reproducing.
In this study, the researchers observed that apigenin's connection to the hnRNPA2 protein restored this single-splice characteristic to breast cancer cells, suggesting that when splicing is normal, cells die in a programmed way, or become more sensitive to chemotherapeutic drugs.
"So by applying this nutrient, we can activate that killing machinery. The nutrient eliminated the splicing form that inhibited cell death," said Doseff, also an investigator in Ohio State's Davis Heart and Lung Research Institute. "Thus, this suggests that when we eat healthfully, we are actually promoting more normal splice forms inside the cells in our bodies."
originally posted by: CryHavoc
Foods with Iodine (mostly seafood) and Garlic help boost the immune system.
originally posted by: dunn00
i found this by accident about 5 years ago . u will not get to many answers if u ask any doctors
here in the USA about this drug .they mostly banned it here because it is so cheap to make.
i have taken this and have no cancer but i have some other issues that claim cancer as a possible
underlying reason. turns out it wasnt cancer as i dont have any but when i researched this pill it says
there are no side effects to be concerned about like the side effects just about every drug made has.
some so bad they require to take other pills just to dull down the side effects from the pill they want
u to use. so i took about 20 or so 100mg only 1 a day basically just for the hell of it and i never felt anything
from this pill to speak of as a side effect. God Bless and hope for a speedy recovery....
this should give u some better info here
Epilogue: Discontinuation in United States
The last manufacturer of mebendazole in the United States, Teva Pharmaceuticals, announced on October 7, 2011, that they have ceased manufacture of this product. As of December, 2011, it is no longer available from any manufacturer in the USA. No reason was given for this discontinuation, but it's blatantly obvious.
originally posted by: infolurker
a reply to: Rich Z
Compound in Mediterranean diet makes cancer cells 'mortal'
Parsley, celery and chamomile tea are the most common sources of apigenin, but it is found in many fruits and vegetables.
www.sciencedaily.com...
By altering a very specific step in gene regulation, this compound essentially re-educates cancer cells into normal cells that die as scheduled.
Through additional experimentation, the team established that apigenin had relationships with proteins that have three specific functions. Among the most important was a protein called hnRNPA2.
This protein influences the activity of messenger RNA, or mRNA, which contains the instructions needed to produce a specific protein. The production of mRNA results from the splicing, or modification, of RNA that occurs as part of gene activation. The nature of the splice ultimately influences which protein instructions the mRNA contains.
Doseff noted that abnormal splicing is the culprit in an estimated 80 percent of all cancers. In cancer cells, two types of splicing occur when only one would take place in a normal cell -- a trick on the cancer cells' part to keep them alive and reproducing.
In this study, the researchers observed that apigenin's connection to the hnRNPA2 protein restored this single-splice characteristic to breast cancer cells, suggesting that when splicing is normal, cells die in a programmed way, or become more sensitive to chemotherapeutic drugs.
"So by applying this nutrient, we can activate that killing machinery. The nutrient eliminated the splicing form that inhibited cell death," said Doseff, also an investigator in Ohio State's Davis Heart and Lung Research Institute. "Thus, this suggests that when we eat healthfully, we are actually promoting more normal splice forms inside the cells in our bodies."
originally posted by: Rich Z
This is a new one to me. But it certainly does look promising. Kind of worried about throwing too much at the cancer and getting drugs interacting together in unpredictable and unpleasant ways, though. But I don't know how much sand is remaining in her hourglass.
She is leaning towards making that trip to Tijuana, Mexico. She knows the clock is ticking, too.
originally posted by: Rich Z
Does anyone here have direct experience with that Oasis Of Hope in Tijuana, Mexico, or know of someone first hand who has been there? I don't trust reviews as much as I used to when they are on review style websites.