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The viral fever is confirmed to have killed at least one person in the country and is linked to another eight deaths, according to the organization. In addition to the nine deaths, there are another 16 suspected cases in the country, with patients exhibiting symptoms that include fever, fatigue, and blood-stained vomit and diarrhea.
In fatal cases, death often occurs between eight and nine days after the onset, usually preceded by blood loss and shock, the agency said.
The virus is highly contagious and bodies can remain contagious even after death.
Marburg virus can be difficult to diagnose given its similar presentation to several other infectious diseases, including malaria, typhoid fever, meningitis, and Ebola. The disease originates from the same virus that causes Ebola.
Authorities in neighboring Cameroon said Wednesday that the country had detected two suspected cases of the disease in a commune that shares a border with Equatorial Guinea.
We won't have to worry about that with Marburg, there is no vaccine or antiviral treatment for this disease.
A newly published paper in The Lancet shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. The vaccine, developed by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, could someday be an important tool to respond to Marburg virus outbreaks.
This first-in-human, Phase 1 study tested an experimental MARV vaccine candidate, known as cAd3-Marburg, which was developed at NIAID’s Vaccine Research Center (VRC). This vaccine uses a modified chimpanzee adenovirus called cAd3, which can no longer replicate or infect cells, and displays a glycoprotein found on the surface of MARV to induce immune responses against the virus. The cAd3 vaccine platform demonstrated a good safety profile in prior clinical trials when used in investigational Ebola virus and Sudan virus vaccines developed by the VRC.
The World Health Organization hopes to test an experimental Marburg vaccine in Equatorial Guinea, which announced its first outbreak of the virus Monday.
On Tuesday, the WHO convened an urgent meeting to evaluate several possible vaccine candidates that could be administered during the outbreak. The meeting brought together a consortium of vaccine developers, researchers and government officials — a group the WHO created in 2021 to advance a Marburg vaccine.
“Everything that we do needs to be done with alacrity," Dr. Philip Krause, the chair of the WHO Covid Vaccines Research Expert Group, said at the meeting. "Even if we’re going to do a study over many outbreaks, the more participants in that study that could be enrolled at each outbreak, the more likely we are to reach a conclusion sooner."
People can spread Marburg virus through blood, other bodily fluids or contaminated objects or surfaces. Past outbreaks, mostly in Africa, have had death rates of 24% to 88%, depending on the virus strain and the strength of efforts to control transmission.
originally posted by: Vroomfondel
a reply to: nugget1
There wasn't any for Covid when it hit, either.
There still isnt...
originally posted by: Vroomfondel
a reply to: infolurker
That is waaaayyyyy too convenient...
originally posted by: 5ofineed5aladder
What if the plan all along was to get the public to mistrust new vaccines, then to unleash a new disease knowing the people will be skeptical about a vaccine.
Marburg is a dangerous virus with roughly a 50% fatality rate and no known treatments.
originally posted by: nugget1
a reply to: Vroomfondel
We won't have to worry about that with Marburg, there is no vaccine or antiviral treatment for this disease.
There wasn't any for Covid when it hit, either.
I think they'd have to GOF Margurg before it could become a world pandemic.