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originally posted by: v1rtu0s0
If a certain group of people are correct then some batches will cause lethality in 3-5 years, and since the military is so highly vaxxt that could decimate the countries ability to defend itself and then China can just stroll in.
originally posted by: LordAhriman
originally posted by: v1rtu0s0
If a certain group of people are correct then some batches will cause lethality in 3-5 years
That's not how it works.
originally posted by: Ksihkehe
originally posted by: LordAhriman
originally posted by: v1rtu0s0
If a certain group of people are correct then some batches will cause lethality in 3-5 years
That's not how it works.
I like how "The Science" has now become a single line response saying "nuh-uh" in anywhere from 1/4 to 1/3 of your posts.
Did you let the long COVID crowd know that chronic conditions are "not how it works"?
I'd love to know what mechanism in "The Science" causes long COVID from infection, but somehow the spike protein proliferation from vaccination is totally benign and doesn't have chronic effects.
originally posted by: LordAhriman
originally posted by: v1rtu0s0
If a certain group of people are correct then some batches will cause lethality in 3-5 years
That's not how it works.
originally posted by: drewlander
Numerous reports have reported that infection with the spike protein (S protein) of SARS-CoV-2 virus can elicits profound functional alterations and damage of ECs [7]. Human lung microvascular endothelial cells (HLMVEC) are activated after infection with the S1 protein or S1 infected human macrophages, evidenced by increased expression of pro-coagulant marker (tissue factor), and cytokines/chemokines (ICAM-1, VCAM-1 and MCP1) [54]. Similar effects were observed in ECs infected with SARS-CoV-2 spike pseudovirions (SCV-2-S) [55]. In addition, S1 subunit of SARS-CoV-2 spike protein (S1) decreased endothelial barrier function in cultured human pulmonary microvascular ECs [22]. Similarly, in human aortic ECs (HAECs) treated with recombinant SARS-COV-2 S protein, increased secretion of inflammatory molecules and marker of thrombosis (IL-6, IL-18 and MCP-1 and PAI-1) were observed [56]. Furthermore, spike protein S1 receptor-binding domain (S1-RBD) infection in mouse brain microvascular ECs induced the degradation of endothelial junctional proteins (VE-Cadherin, junctional adhesion molecule-A, Connexin-43 and PECAM-1), thereby impaired endothelial barrier function and caused vascular leakage and endotheliitis in COVID-19 patients [57, 58]. These findings suggest that spike protein interactions with ECs contribute to inflammation, thrombosis, and the severity of COVID-19 and could offer novel mechanistic insights into SARS-CoV-2 induced vascular leakage and the development of targeted therapies
Our results show that in control cells and in healthy mouse cerebral arteries, spike protein triggered downregulation of critical junctional proteins, VE-Cadherin, PECAM-1, JAM-A, and Connexin-43. The expression of these proteins appeared to be downregulated in diabetic cells and diabetic mouse cerebral arteries when compared to control but spike induced a further reduction in protein expression. Co-immunoprecipitation experiments showed that in control cells, spike treatment increased association of ACE2, PECAM-1, JAM-A, and Connexin-43 with the endocytic trafficking protein, Rab5a. An endothelial permeability assay also revealed increased permeability in diabetic cells which further increased in the presence of spike protein. These early results showed that spike protein not only binds to endothelial ACE2 to induce its degradation but also likely triggered additional dysfunction by downregulation of endothelial junctional proteins.
mRNA vaccination stimulates robust GCs containing vaccine mRNA and spike antigen up to 8 weeks postvaccination in some cases.
originally posted by: v1rtu0s0
If a certain group of people are correct then some batches will cause lethality in 3-5 years, and since the military is so highly vaxxt that could decimate the countries ability to defend itself and then China can just stroll in.
originally posted by: drewlander
a reply to: LordAhriman
That is not how a rebuttal works. Please expand on why vaccines cannot not work this way for my edification on this topic from a master debater.