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Still, the outbreak virus diverges a mean of 50 SNPs from those 2018-2019 viruses (46 SNPs from the closest reference MPXV_UK_P2, MT903344.1) (Table 1_2022-05-23.zip (15.0 KB)), which is far more than one would expect considering the estimated substitution rate for Orthopoxviruses (3).
While APOBEC3 is associated with cellular resistance (yet another form of “innate immunity”) to HIV (and presumably other retroviruses), a quick PubMed search reveals that Poxviruses are resistant to the mutational effects of APOBEC3!
For example, see this 2006 paper published in “Virology”. Frankly, whether through lack of curiosity or fear of attack from government-controlled media and journals, the failure of the authors to even mention this Virology article is a major oversight at best.
Furthermore, this double-stranded DNA virus, infections by which have historically been self-limiting, appears to be evolving (during the last few days!) to a form that is more readily transmitted from human to human.
originally posted by: rickymouse
The Wuhan lab is probably not the only lab that has been working with the Monkey Pox. I am sure there are multiple labs working with this and other dangerous microbes around the world. Lab leaks do happen. They have a vaccine for this already, so think about this, how could they have a vaccine that quick for it if they knew nothing about it till just a little while ago.
originally posted by: 1947boomer
originally posted by: rickymouse
The Wuhan lab is probably not the only lab that has been working with the Monkey Pox. I am sure there are multiple labs working with this and other dangerous microbes around the world. Lab leaks do happen. They have a vaccine for this already, so think about this, how could they have a vaccine that quick for it if they knew nothing about it till just a little while ago.
Monkeypox was first discovered in humans in 1958:
www.cdc.gov...
The vaccine for Monkeypox is the same vaccine as for Smallpox, because the two viruses are very similar to each other. In general, Smallpox vaccines have been around a long, long time. One of the two current pox vaccines approved for use in the US was approved in 2007:
en.wikipedia.org...
This "new" antiviral treatment for Smallpox/Monkeypox (TPOXX) isn't actually new. It's the same compound that was approved for oral administration (pills) in 2018. What's new is that it is now approved for intravenous administration:
en.wikipedia.org...
Confirmation Native American Remedy Indeed Kills the Variola Virus! The remedy went largely forgotten for the next century. But in 2012, researchers at Arizona State University took a fresh look at the old remedy and conducted in vitro experiments with a Sarracenia extract. They found that it inhibited the replication of the variola (smallpox) virus. The study, published in the journal PLOS ONE, concluded that “S. purpurea is the only known therapy that will target the virus at this point in the replication cycle.”
originally posted by: buddha
They do Not wont to kill a lot of people!
they could do that easly.
its to scare You!
they would test it on Lots of humans first.
How many people disappear a year!
originally posted by: Inbangstickitin
a reply to: rickymouse
It's proper trash isn't it? We just seem to be in a perpetual state of being played.
I mean.... Come on man! Stop being pricks. We pay our costs, we ain't hurting anyone. Let us be!
The Soviet Union’s biological warfare program, with far less sophisticated equipment and knowledge than we have today, produced a host of biowarfare agents. This effort included 65,000 researchers in a vast network of secret laboratories, each focused on a different deadly agent. They produced traditional biological weapons and may have successfully combined smallpox, Marburg, Ebola, and other viruses. If someone could combine the 90-percent-lethal Ebola virus with highly contagious smallpox, one might indeed create an existential BVP. A former leader of the Soviet biowarfare program believes his colleagues still work in Russia and many other nations, and predicts that bioweapons “in the coming years will become very much a part of our lives.”4
originally posted by: gspat
Maybe the solution is cowpox?
Cowpox made it so smallpox was a thing of the past.
originally posted by: TarantulaBite
originally posted by: gspat
Maybe the solution is cowpox?
Cowpox made it so smallpox was a thing of the past.
Just seen this
‘Pretty nasty’ Monkeypox likened to cowpox by scientist as two strains emerge - LINK
And here they are saying NO it's NOT from a LAB
Monkeypox wasn’t created in a lab - and other claims debunked
LINK
originally posted by: Ravenwatcher
Waiting for the Airborne Ebola ............ 3-2-1