This post is a follow up to other posts I've made. I'll post links to them here, if readers need or want more background on the subject matter:
Capping and liver DNA uptake:
Wisenox Capping
Moderna patent 10703789:
Wisenox Moderna
In continuation, I believe I have found the mechanism of liver delivery, why the liver and spleen show high volumes of spike proteins, and why PEG is
included in the vaccine.
One of the primary objectives of the vaccines is to evade our innate immunity. Moderna's patent spells out the capability they designed into it:
As described herein, a useful feature of the polynucleotides, primary constructs or mmRNA of the invention is the capacity to reduce, evade or
avoid the innate immune response of a cell.
The process begins with mRNA capping.
In short, the mRNA is being capped as 'self' to purposely evade the innate immune system. Pfizer is using the LINE1 retrotransposon for reverse
transcription, and Moderna is synthetically adding the capping mechanism. These are explained in more detail in the above mentioned posts.
Evading our immunity is essential for at least 3 reasons: 1. so the spikes survive by being capped as 'self'. 2. so the macrophages in the liver
and spleen don't eliminate the vaccine nanoparticles, and 3. (from the Moderna patent):
In some embodiments of the invention, polynucleotides, primary constructs or mmRNA are provided to express a protein associated with human
disease.
That's right, the Moderna technology is also designed to induce illness.
The Swedish study finding the spike proteins in the liver is well known by now, but the method of delivery to the liver and the importance of the
organ are relatively unknown.
Quotes from here are from:
Therapeutic targeting of liver inflammation and fibrosis by nanomedicine
1) How does it get to the liver?
The Moderna patent explains how monoclonal antibodies are created to target chemokine and mannose receptors in the liver (also found in spleen). The
process involves conjugating a
targeting group to the monoclonal antibody.
In one embodiment, primary constructs or mmRNA disclosed herein may encode monoclonal antibodies and/or variants thereof.
The targeting group can be any ligand that is capable of targeting a specific receptor. Examples include, without limitation, folate, GalNAc,
galactose, mannose, mannose-6P, apatamers, integrin receptor ligands, chemokine receptor ligands, transferrin, biotin, serotonin
receptor ligands, PSMA, endothelin, GCPII, somatostatin, LDL, and HDL ligands.
Seratonin receptors are found in the brain, which is also disturbing.
2) Why the liver [and spleen]?
This is where it gets interesting:
Macrophages and especially the liver-resident Kupffer cells are in the focus of nanomedicine due to their highly efficient and unspecific
uptake of most nanomaterials as well as due to their critical pathogenic functions during inflammation and fibrogenesis. The mannose
receptor enables targeting macrophages in liver disease, but macrophages can also become activated by certain nanomaterials
Reason one for the liver and spleen: because they remove the nanoparticles efficiently. This is important because
90% of all macrophages
reside in the liver. The spleen would probably compete were it as large as the liver.
Reason two for the liver, or more specifically
the macrophages, is their "
pathogenic functions":
Nanomaterial uptake was shown to alter the state of macrophage activation (also termed polarization) and thereby to affect the profile of their
cytokine release in vitro and in vivo (16,23). Cytokine levels are important mediators of tissue injury and inflammation and can therefore also be
considered as biomarkers for disease activity.
Reason two is to cover their tracks.
So, what other functions may these liver cells have?
Monocytes, macrophages, and specifically dendritic cells have an additional bridging function for the activation of adaptive
immunity.
This is the second time the vaccine purposely evades our innate immunity, except this time they actually shut it down so it doesn't produce biomarkers
that would raise alarms; very sinister. They shut down the macrophages by switching their function between restorative and proinflammatory
responses.
3) Why PEG?
That's simple, to evade immunity...again:
To prevent the attachment with serum proteins, many nanoparticles including gold-based systems are PEGylated to reduce their unspecific
uptake by phagocytes by evoking a neutral charge.
Macrophages are activated by positive charge. PEGylation increases the lifespan of the nanoparticles by evading our immunity.
There is a lot more to cover from the patent information. For example, they can add more than 30 sub-group RNA's at the same time.
Meaning, they can cause or induce just about any illness or cancer while also causing spike production. We would never know, and they can cause them
simultaneously.
For an idea of what that could be, read Virtuoso's post about the CYP19 and CDKN1B gene modifcations:
v1rtu0s0 CYP19/CDKN1B
CYP19 is responsible for steroid biogenesis (aromatase). Without it, female offspring will be sterile, get premature ovarian cancer, and may not even
develop a uterus or vagina. Men will also be sterile. CDKN1B plays a role in prostate cancers.
In my opinion, this is a smoking gun that the vaccines are premeditated democide/genocide/murder. There is no chance on Earth that this technology
was produced within the fraudulent
warp speed lie. I also believe that this information should nullify any immunity given, but that's for a
lawyer to look at.
Another grave concern is that this technology can be packaged into
any recombinant vaccine.
In 2019, just a couple months before the planned
pandemic Trump signed an Executive Order mandating that every state actively promotes
'Recombinant Flu Vaccines'. They're planning on doing more of this to us.
My advice, don't! You simply can't trust the puppeted murderers in office that will allow the elites to sterilize, murder and induce terminal
illnesses in their citizens.
Shame too, because some really wonderful things could be achieved with the technology.
edit on 12-3-2022 by Wisenox because: General clean up.