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originally posted by: AugustusMasonicus
Yeah, because I like rolling the dice when it comes to medical, financial and legal advice.
You think they post this for feels or because following the advice of internet randos could be harmful?
We'll, if I were you I'd certainly rely on my homebrew remedies over a trained and licensed physician. Or you could doctor shop until you find someone who agrees with you. Either way, YOU aren't a physician and your medical advice and everyone else's on here is anecdotal.
originally posted by: SinDefiant
So my wife and I tested positive for covid today. We've been careful but it's just one of those things. I'm going to get some zinc for sure. Was thinking about getting ivermectin and/or hydrochloroquine. Wanted to know what you guys think. We've got 2 8 month old twin babies so going down isn't really an option we need to take this on our feet.
originally posted by: tamusan
Trained and licensed physicians will normally stop short of giving medical advice on an online forum that isn't specifically for medical advice.
I almost told them to call their own doctor, but that kind of advice usually gets me flamed on here. I felt that I should at least warn them about fake ivm and hcq.
originally posted by: StaticVoid
Eating your shoe would probably be well tolerated as well, but it wont cure you of COVID.
The editors of Frontiers in Pharmacology have taken down an article about the use of the antiparasitic drug ivermectin in COVID-19 patients. The paper, which was written by members of an organization called the Front Line COVID-19 Critical Care Alliance (FLCCC), had been provisionally accepted and posted in abstract form by the journal in January, but was ultimately rejected this Monday (March 1). The editors determined that it contained unsubstantiated claims and violated the journal’s editorial policies.
originally posted by: StaticVoid
a reply to: The GUT
And that paper was rejected.
Summary of the Evidence for Ivermectin in COVID-19
originally posted by: StaticVoid
Its not cherry picking, its what we've been discussing, the scientific method in action. The research was published, peer reviewed, and rejected on basic scientific principles. QED
originally posted by: The GUT
originally posted by: StaticVoid
Its not cherry picking, its what we've been discussing, the scientific method in action. The research was published, peer reviewed, and rejected on basic scientific principles. QED
As should be any study that has flawed methodology. But there are many studies that are solid. And yes you are cherry-picking. Flagrantly. But your reputation here is your own responsibility.
Do you have a problem looking at them and considering the evidence?
Because so far it's obvious you know very little about the pros vs cons and the excellent research that has survived peer review.
originally posted by: StaticVoid
How about you point them out then rather than casting judgement on me? You posted a link, I countered it, this is how logical debate works.
Currently, as of September 19, 2021, the totality of the evidence is as follows.
• IN-VITRO (BASIC SCIENCE): ivermectin has been shown to inhibit the replication of many viruses, including West-Nile, Zika, Dengue, Influenza, and most recently SARS-CoV-2 [1,2,3,4,5,6,7]
• IN-VIVO: ivermectin diminishes viral load and protects against organ damage in animal models of SARS-CoV-2 infection and has multiple, potent anti-inflammatory and immune- modulating properties [1, 2, 3]
For more information about the FLCCC Alliance and our Prevention & Treatment Protocols for COVID-19, please visit www.flccc.net
Page 2 / 3
• IN-SILICO: numerous computer modeling studies have found ivermectin to have one of the highest binding affinities to the SARS-CoV-2 spike protein
• PHARMACOLOGIC: unparalleled safety profile over decades, prior WHO guidelines report side effects that are “primarily minor and transient” and experts have found severe adverse events to be “unequivocally and exceedingly rare.” Further, the IC-50 against SARS-CoV2 in lung and adipose tissue easily achieved with standard dosing (Caly/Wagstaff personal communication)
• CLINICAL OBSERVATIONS/EXPERIENCE: numerous cases series, most notably one published from the Dominican Republic in June 2020 where over 3,000 consecutive patients presented to the ER, were treated with ivermectin, and only 16 were hospitalized and only 1 died. Also, innumerable doctors from multiple countries around the world report observing consistent clinical responses in treated patients with few treatment failures.
• OBSERVATIONAL CONTROLLED TRIALS (OCT): As of August 8, 2021, the results from 31 OCT’s including over 6,800 patients find that treatment with ivermectin reduces time to recovery, rates of hospitalization, and mortality, the latter finding best reported in the sophisticated propensity-matched study of Rajter et al. published in the major medical journal Chest.
• META-ANALYSES OF RANDOMIZED CONTROLLED TRIALS (RCT): 27 RCT’s including over 3,400 patients have been completed. Meta-analyses find that ivermectin reduces time to viral clearance, hastens recovery, and reduces mortality.
• OBSERVATIONAL AND RANDOMIZED TRIALS IN THE PREVENTION OF COVID-19: A series of 13 RCT’s and OCT’s consistently find that single or repeated ivermectin use strongly reduces the risk of contracting COVID-19, with an average level of protection of 86% with higher levels of protection found amongst the trials with more frequent dosing [1,2,3,4,5,6,7(Table 2), 8,9,10,11,12].
• EPIDEMIOLOGIC: ivermectin distribution campaigns in Peru led to far lower COVID-19 case- fatality rates in those regions with widespread use. Further, large “test and treat” programs conducted by increasing numbers of Health Ministries report up to 75% reductions in the need for hospitalization (Mexico City) and massive reductions in mortality (Misiones, Argentina and La Pampas, Argentina). Finally and most importantly, the Indian state of Uttar Pradesh (pop. 241 million) has effectively eradicated COVID via systematic and widespread use of ivermectin in both prevention and early treatment.
The reports most relevant to public health officials are from the national and regional health ministries that employed either distribution or “test and treat” programs with ivermectin:
• Mexico City – The IMSSS Health Agency compared over 50,000 patients treated early with ivermectin to over 70,000 not treated and found up to a 75% reduction in need for hospitalization.
Page 3 / 3
• Peru – A nationwide mass-distribution program called “Mega-Operación Tayta” (MOT), initiated at various times across 25 states of Peru in May 2020, led to a 74% drop in regional excess deaths within a month, with each drop beginning 11 days after each MOT region’s varied start times
• La Pampas, Argentina – Health Ministry compared over 2,000 patients they treated early with ivermectin to over 12,000 without treatment and found a 40% reduction in hospitalization and 35% less ICU or death in older patients
• La Misiones, Argentina – Health Ministry just analyzed the first 800 of 4,000 ivermectin treated patients and compared to the rest of the population over the same time period, they found a 75% reduction in need for hospital and an 88% reduction in death.
• Uttar Pradesh, India – Used a strategy of close surveillance combined with both ivermectin treatment of all positive cases and preventive treatment of all family contacts. On September 10, 2021, only 11 cases with no deaths were recorded in a population of 241 million.
As of August 31, of the previous 187,638 tests performed, only 21 were positive, an essentially zero positive rate or .01%.
Finally, in both “long-haul” COVID and post-vaccine syndromes, ivermectin is proving to be highly effective at eliminating symptoms based on the rapidly accumulating clinical experiences of the FLCCC and a number of allied experts that co-developed the I-RECOVER protocol, centered around the use of ivermectin in these syndromes.
CONCLUSION
Based on the totality of the existing evidence above, the FLCCC strongly recommends ivermectin be used in both the prevention and treatment of all phases of COVID-19 in both vaccinated and unvaccinated populations.
So far y'all are just bitching without apparently having done much, if any, reading of the peer-reviewed research. And then wanna criticize others for having the maturity & due-diligence to do so.edit on 15-12-2021 by The GUT because: (no reason given)