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When the smoking cessation medication, Chantix, was trending on Twitter Monday, it quickly became apparent that it wasn’t just because the manufacturer had recalled it. Yes, the recall of the drug (generic name: varenicline) was making headlines, but many were using those headlines to make a different point: arguing that the recall reinforces the idea that you can’t trust the safety of medications. Specifically, some argued, the recall meant you can’t trust the Covid-19 vaccine.
By this point, the possible side effects of the Covid-19 vaccine, of which 43.5 percent of the world has now had at least one dose, are pretty well established. Anti-vaxxers want to make it seem like there was this deadly chemical in Chantix all along, but that’s a bit like saying no yogurt from the supermarket can be trusted because once you got one that had mold on the top. Gross, yes. A possible indication that others are contaminated, yes, but “all the yogurts in the history of this brand have mold?” Not so much.
On average, about 4,500 drugs and devices are pulled from U.S. shelves each year. The recalled products have U.S. Food and Drug Administration (FDA) approval and in many cases, are widely ingested, injected or implanted before being recalled. Although the FDA may identify concerns regarding the safety of a drug, it is the responsibility of the manufacturer to initiate and execute a recall. On the other hand, the FDA can mandate the recall of a device.
2000--2008: A total number of drugs approved were 209. Out of these, 9.09% of drugs like fondaparinux, ranolazine, etc., were indicated for cardiovascular disorders. 12.91% of drugs were approved for neurological disorders namely rivastigmine, aripiprazole, etc., Antibiotics (5.26%) and antivirals (5.74%) were least contributed, anticancer drugs (11.96%) and biologics (7.17%) approval remained constant during these years.[5] These results reflect that less number of Investigational New Drug Applications (INDA) are being filed pertaining to antibiotic/antiviral category. It could be because of research and developments of pharmaceutical giants are focused on other categories of drugs or failure of New Chemical Entity (NCE) during development. Some landmark drugs during this period are mentioned in Table 1.
2009--2017: Total number of drugs approved was 302. Out of these, 5.29% of drugs like prasugrel, rivaroxaban, etc., were indicated for cardiovascular disorders. This is relatively less as compared to previous years, i.e. a fall of 4% approximately. 9.93% of drugs were indicated for neurological disorders namely perampanel, pimavanserine, etc. In neurological indications, again a fall of 3% approximately is observed as compared to previous years. Antibiotics (5.29%) and antivirals (5.96%) were least contributed, whereas anticancer drugs (17.54%) and biologics (15.56%) approval took a steep rise. Some important drugs approved during these years are highlighted in Table 2. We observed that limited numbers of drugs are being approved for lifestyle disorders like diabetes, obesity, cardiovascular disorders, etc., Presently, more number of anticancer drugs and biologics are being approved compared to drugs required for lifestyle diseases, antibiotics, respiratory disorders, etc.
May 18, 2006 — The US Food and Drug Administration (FDA) has approved varenicline tartrate tablets for use as an aid to smoking cessation treatment.
It's sad to say that it doesn't really work like that in real life does it.
originally posted by: nonspecific
It's well documented online and also here I think.
In short they made a car that they knew could catch fire if rear ended and would cost about 10 dollars to fix but didn't bother as it was expensive on so many vehicles.
There was a leaked document where they discussed how it was cheaper to pay compensation to anyone that died in fires caused by the defect than it was to fix them all.
a reply to: Wide-Eyes