Why Clotting Happens When Platelets Are Low

Appears the Johnson and Johnson shot is no worse than others for this kind of thing. The AstraZeneca seems to clearly be the frontrunner. Of course, this is only incidents which they "count" so we really have no idea of the totals. A very good article explaining what his happening with these vaccine-induced immune thrombotic thrombocytopenia.


www.medpagetoday.com...

The European Medicines Agency has said that, as of April 20, there have been 287 reports of rare blood clots with low platelets after administration of the AstraZeneca vaccine, eight with Johnson & Johnson, 25 with Pfizer, and five with Moderna.

Two Distinct Processes Lead to Low Platelets

In general, two distinct processes can result in thrombocytopenia, or low platelets. The first process involves platelet clearance, and it's an immune process. "With clearance, the body's immune system actually destroys the platelets, which brings the platelet count down and can lead to bleeding," Gaddh said.

The second process involves consumption of platelets when they become activated, and go about their normal job of stimulating the clotting system and aggregating to form blood clots. If the consumptive process gets out of control, platelets get used up and their numbers drop.

"In consumption, platelets are actually getting activated. That activates the clotting system to make the platelets aggregate together, which brings down the platelet count and favors clotting in the body," Gaddh said.

When it comes to management, because of the similarity of VITT to HIT, experts are advising IV immunoglobulin, use of non-heparin anticoagulants, and avoidance of platelet transfusions. The International Society on Thrombosis and Haemostasis has provided guidance for the diagnosis and treatment of VITT, as has the American Society of Hematology.

www.reuters.com/business/healthcare-pharmaceuticals/european-medicines-agency-more-than-300-cases-rare-blood-clot-events-worldwide-2021-04-20/

The European Union’s drug regulator said on Tuesday there had been more than 300 cases worldwide of rare blood clotting incidents combined with low platelet counts after use of COVID-19 vaccines.

There were 287 occurrences with the AstraZeneca vaccine, eight with Johnson & Johnson’s shot, 25 for Pfizer and five for Moderna, said Peter Arlett, Head of Data Analytics at the European Medicines Agency (EMA).

A virus, or even a vaccine, can trigger agglutination of platelets even if they are not low. In the presence of a microbe, the elements of the blood get stickier as part of how they grab microbes to get rid of them. Just eat more onions, onions reduce blood clotting effect, and when eaten raw, they can even help to break up clots a little. That is one of the properties of onions. Too much onions can lead to bleeding too, so be reasonable. I have had a problem regulating blood since I was a teenager, I learned what to eat or not eat long ago. Been doing it all my adult life and I do not need a blood test to let me know when my blood is too thick, yet I cannot explain to anyone how I know I need some chemistry to thin or thicken it. The doctor explained it to me when I was young and I looked stuff up and adjusted my diet...so long ago it is normal to eat this way now, I get cravings for something and eat it or something similar. We are never out of onions or garlic in this house, and I always have both garlic and onion powders in the pantry just in case something happens.