Hydroxychloroquine Still Doesn’t Do Anything, New Data Shows

a reply to: asabuvsobelow

I work in a Hospital , I'm a nurse yes HydroxyCloroquine does work I'll say it again yes it does work . Is it a cure all ? no

No, it's not a cure for all.

I think I've made it clear the OP isn't about discounting HCQ as an effective treatment for other illnesses, ailements. If anything, that's part of my grip with people insisting HCQ is a treatment against COVID19:

Hydroxychloroquin e shortage a pain for Bengaluru arthritis patients

Sudden Hydroxycholoroquine Shortage Is Forcing Indian Doctors To Make Tough Choices

Shortages of Hydroxychloroquine for Lupus Patients

There's are a number of dangers about spreading misinformation on supposed miracle cures, treatments.

It's been pointed out time and time again that it's not an effective treatment against COVID19. As a nurse you should be well aware of the dangers on spreading medical misinformation out there. This is a serious pandemic, 160k plus dead. You shouldn't be messing around with peoples lives here.

He,s no medical doctor far from it , I told you you would get trolled, He,s not took in a word you said,That should tell you everything you need to know about him.Do yourself a huge favour and ignore him reply to: asabuvsobelow

No one is listening to what you are saying FlyersFan,they dont want to entertain the fact that it may help against covid , They are politicising it,Antitrumpers first and foremost, and cant bare the thought that trump may have said something that may point towards a drug working,I,ve been watching all the covid and Hydroxy posts from the start of this crisis and its plain to see reply to: FlyersFan

originally posted by: themove1904
No one is listening to what you are saying FlyersFan ...

They never do.
But they should.
Pffft ...

originally posted by: themove1904
He,s no medical doctor far from it , I told you you would get trolled, He,s not took in a word you said,That should tell you everything you need to know about him.Do yourself a huge favour and ignore him reply to: asabuvsobelow

your not wrong he is simply seeing what he wants to see.

originally posted by: Southern Guardian
a reply to: asabuvsobelow

I work in a Hospital , I'm a nurse yes HydroxyCloroquine does work I'll say it again yes it does work . Is it a cure all ? no

No, it's not a cure for all.

I think I've made it clear the OP isn't about discounting HCQ as an effective treatment for other illnesses, ailements. If anything, that's part of my grip with people insisting HCQ is a treatment against COVID19:

Hydroxychloroquin e shortage a pain for Bengaluru arthritis patients

Sudden Hydroxycholoroquine Shortage Is Forcing Indian Doctors To Make Tough Choices

Shortages of Hydroxychloroquine for Lupus Patients

There's are a number of dangers about spreading misinformation on supposed miracle cures, treatments.

It's been pointed out time and time again that it's not an effective treatment against COVID19. As a nurse you should be well aware of the dangers on spreading medical misinformation out there. This is a serious pandemic, 160k plus dead. You shouldn't be messing around with peoples lives here.

Mate your right there are a number of dangers about spreading medical mis-information.

Like for example thousands of people in New York City hospitals dying with respirators down there throats because the Doctors could not get there hands on or were scared to death to use Hydroxychloroquin because of the media . These doctors had no idea how to treat these patients and were killing them by the boat loads because of it.

All the while a treatment of Pure Oxygen , Hydroxychloroquin and Erythromycin could have saved thousands of people but no these people died .

And do you know why they died ? Money , Politics, Ignorance , misinformation and fear.

a reply to: asabuvsobelow

Like for example thousands of people in New York City hospitals dying with respirators down there throats because the Doctors could not get there hands on or were scared to death to use Hydroxychloroquin because of the media

Why hydroxychloroquine and chloroquine don’t block coronavirus infection of human lung cells

2005 chloroquine study had nothing to do with COVID-19 and the drug wasn’t given to humans

The 2005 study wasn’t published by the NIH and didn’t prove chloroquine was effective against “COVID-1” because that’s not a real disease.

The study found that chloroquine could inhibit the spread of Severe Acute Respiratory Syndrome in animal cell culture, and the authors said more research was needed.

There are currently no approved medications or treatments for COVID-19.

The World Health Organisation: Studies show hydroxychloroquine does not have clinical benefits in treating COVID-19

PolitiFact - Yes, at least five randomized controlled studies say hydroxychloroquine doesn’t help

MedRxIV, HCQ findings

Chloroquine does not help against the coronavirus

research findings by scientists from the German Primate Center (DPZ) in Göttingen, the Charité in Berlin and the University Hospital in Bonn now speak a very clear language: Chloroquine is not suitable for the treatment of SARS-CoV-2 infections. It simply does not work.

Authors retract hydroxychloroquine study

WHO says trials show malaria and HIV drugs don't cut Covid-19 hospital deaths

Hydroxychloroquine flunks Phase III trial in mild-to-moderate Covid-19

NIH halts clinical trial of hydroxychloroquine

Birx: FDA 'has been very clear' on its concerns about using hydroxychloroquine as COVID-19 treatment

NIH halts clinical trial of hydroxychloroquine

Large-scale study finds Turkey’s favoured COVID-19 treatment linked to sudden death

Trump Coronavirus Taskforce member, Fauci: Science shows hydroxychloroquine is not effective

Brazilian chloroquine study halted after high dose proved lethal for some patients

Basel study: hydroxychloroquine not effective

Three big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19

You're right about thousands of people dying in the US. That responsibility lies mostly with an incompetent government and whitehouse. The same government posters like yourself here continue to indirectly cover for through your defense of HCQ claims.

Thanks 'mate'. Take it easy on the

a reply to: asabuvsobelow

your not wrong he is simply seeing what he wants to see.

Ding! Ding! Ding! We have a winner!

I for one appreciate your input as a medical professional.

TheRedneck

a reply to: Southern Guardian

All those links and studies are impressive .

Did you write any of them , or conduct any of the studies ?

Do you simply dismiss the fact I'm telling you that I've seen Hydroxychloroquine play direct roles in the recovery of Covid patients ?

a reply to: asabuvsobelow

What controls were used? What were the demographics of the patients?

What, other than your intuition, indicates that the treatment was more effective than no treatment?

A Sound Approach: Hydroxychloroquine Reduces Mortality in Severe COVID-19


Says published Jul 31st so is it the same one as Fauci said "that the study wasn’t a randomized, placebo-controlled trial, which he called the gold standard for such studies."

"He went on to say that none of the randomized, placebo-controlled trials have shown any efficacy of hydroxychloroquine for use in treating coronavirus patients."

seems strange he promotes Veklury® (remdesivir), which was a non-randomised company controlled study. That also had randomized studies findings that so no efficacy - Remdesivir for Covid-19: $1.6 Billion for a “Modestly Beneficial” Drug?

For those that want to look further it appears in that report says

As the first line of defense, it should be immediately, freely, and widely available to symptomatic high-risk patients – through doctors’ offices, outpatient clinics, and hospitals across the land.

Indeed, under the directorship of Dr. Anthony Fauci, a National Institute of Allergy and Infectious Diseases (NIAID) a clinical trial had been launched on May 14 to look into it.[2]

The HCQ + azithromycin protocol is being used successfully by France’s top, award-winning microbiologist, Dr. Didier Raoult. He is director of the Infectious and Tropical Emergent Diseases Research Unit in Marseille (Institut Hospitalo-Universitaire) (IHU), with 200 staff. Raoult, now almost a celebrity in France, has recently published his protocol and results, showing an overall 1.1% case fatality rate.[3]

The same protocol has also been highly successful in China, India, Senegal, and Brazil.[4]

It also points out

The following day, April 11, the Science Media Centre published expert reactions to the compassionate study from five British university professors. These assessments were not encouraging: “the research doesn’t prove anything at this point;” “the data is almost uninterpretable;” the research should be treated “with extreme caution.”[11]

A Wuhan, China randomized, double-blind, placebo-controlled trial of 237 patients was accidentally leaked by the World Health Organization and published in The Lancet. It showed no statistically significant clinical benefits from remdesivir:
“The antiviral medicine remdesivir from Gilead Sciences failed to speed the improvement of patients with Covid-19 or prevent them from dying, according to results from a long-awaited clinical trial conducted in China.” [12]

This Lancet study also found that some 14% of patients in the treatment group died after 28 days, compared to 13% in the group that did not receive the treatment.

And it further reported that “remdesivir was stopped early because of adverse events in 18 (12%) patients versus four (5%) patients who stopped placebo early.”[13]

The preliminary results of a NIAID remdesivir trial of 1063 patients showed a “modest” benefit in a controlled clinical trial:

Difficult to follow the treatments and the $.
1. long time academic administrator flip flopping around treatments and advice on things he supposedly trained for years to be prepared for.
2. compared to doctors dealing with live patients that may die if they don't try something.

Trial reports by WHO and Industry funded experts seemed to be very misleading they say great things about $$$$Drug but crap on $Drug that has the same or better results.

Anyone else puzzled cause I am 2.

originally posted by: Phage
a reply to: asabuvsobelow

What controls were used? What were the demographics of the patients you have been involved with?

Controls ? That differs patient to patient

Demographics mainly 60-80 years of age male and females alike are the typical patient , The most critical part of the treatment if I understand the physician's correctly is the time frame . It's critical that the virus is treated before the breathing issues start or become serious , Covid starves the body of oxygen now how exactly it does this I don't know but that is the cause of the lung issues .

The earlier the Hydroxychloroquin is administered the better , Mind you this is a Private Hospital I'm talking about Not a State ran Hospital.

a reply to: asabuvsobelow

Controls ? That differs patient to patient

Then there is no control. No way of knowing if the treatment has any effect.

Covid starves the body of oxygen now how exactly it does this I don't know but that is the cause of the lung issues

You may have cause and effect reversed.

a reply to: asabuvsobelow

All those links and studies are impressive .

Did you write any of them , or conduct any of the studies ?

Why on Earth would I write them? I don't pretend to be a doctor, nurse or scientist. I actually refer to the experts who know about studies and know how to run vaccine trials. Maybe some people can take a page out of the humble book and stop pretending to be internet experts on a conspiracy forum. Maybe then we can have an honest, facts based, debate.

originally posted by: Phage
a reply to: asabuvsobelow

Controls ? That differs patient to patient

Then there is no control. No way of knowing if the treatment has any effect.

Covid starves the body of oxygen now how exactly it does this I don't know but that is the cause of the lung issues

You may have cause and effect reversed.

It differs because each patient is different , the hospital is not conducting a drug trial . They are treating patients needs as they arise, they are not simply throwing the drug at every one who has Covid that would be a waste and dangerous.

And as for the lungs , The first thing being noticed is the Oxygen saturation levels of the blood . The body cant find Oxygen so the lungs are running on insufficient fuel as it were so they begin to break down. Then comes the respirator to force work the lungs which in turn inevitably kills the patient .

originally posted by: Southern Guardian
a reply to: asabuvsobelow

All those links and studies are impressive .

Did you write any of them , or conduct any of the studies ?

Why on Earth would I write them? I don't pretend to be a doctor, nurse or scientist. I actually refer to the experts who know about studies and know how to run vaccine trials. Maybe some people can take a page out of the humble book and stop pretending to be internet experts on a conspiracy forum. Maybe then we can have an honest, facts based, debate.

I'm a nurse that's hardly an expert.

a reply to: asabuvsobelow

It differs because each patient is different , the hospital is not conducting a drug trial .

Then there is no way to know if the drug has any effect. Most people get better, with or without treatment.

The body cant find Oxygen so the lungs are running on insufficient fuel as it were so they begin to break down.

Or perhaps the disease is causing the lungs to lose their ability to extract oxygen from the air and provide it to the bloodstream. That's usually what occurs with lung problems. Pneumonia, for example.

You're a nurse? You don't know what the lungs do?

www.webmd.com...

a reply to: asabuvsobelow

It's critical that the virus is treated before the breathing issues start or become serious , Covid starves the body of oxygen now how exactly it does this I don't know but that is the cause of the lung issues .

The virus has a side effect that is being studied. It produces a byproduct during replication that can dislodge the iron atom from hemoglobin, making oxygen transport by affected red blood cells impossible.

COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review

Concerning iron dysmetabolism in COVID-19, Ehsani has highlighted a remarkable similarity between the distant amino acid sequence of SARS-CoV-2 spike glycoprotein cytoplasmic tail and the hepcidin protein. Coronaviruses recognize host receptors using their spike proteins, facilitating conformation transition, so to bind cell membrane and enter host cytoplasm; by using host furins and proteases, coronaviruses may cleave their spike polypeptides, thus favoring the cell entry. The found hepcidin mimicry by the virus would take place through this complex mechanism.

Hepcidin is the master regulator of iron metabolism, interacting with ferroportin to favor iron entrance inside the cells; in case of hepcidin-like activity of SARS-CoV-2 a significant iron dysmetabolism may occur, with hyperferritinemia and ultimately ferroptosis.

In essence, it destroys the blood and causes oxygen deprivation that way as well... acute anemia, much more acute than any anemia we are used to seeing,

TheRedneck

a reply to: TheRedneck

We speculated that in COVID-19, beyond the classical pulmonary immune-inflammation view, the occurrence of an oxygen-deprived blood disease, with iron metabolism dysregulation, should be taken in consideration.

The primary problem with advanced COVID-19 is lung inflammation. Pneumonia. This is not speculation.

But sure, treat it with vitamin C. That's the ticket.

The translational medicine-based speculative reasoning provided in this review may represent a contribution to stimulate future studies, so to corroborate or disprove our original elaboration.

Gobbledy, meet gook.

a reply to: Phage

Regardless of how you look at it Phage the o2 blood saturation is the first thing as a Nurse that I notice why it's happening is not up to me to determine and how to treat it again is not up to me I simply report said levels to the Physician on call or on my floor some Doctors are more proactive than others .

I don't need web md to tell me what I see every day.

and i'm not a pulmonologist