a reply to:
spacedoubt
The original emergence of H1N1 is.. well.. Scary. H5N1, more recently, was a helluva thing too.
So, when folks say "its just a flu,"
or "its not just a flu!" ..They both miss the mark for me.
The asymptomatic carriers are a troubling aspect, but my intuition on that (for what its worth) is that a broad base of relatively low impact carriers
could end up being very beneficial long term. It allows many immune systems, collectively, to familiarize with the virus even if they are spreading it
in the process. It really is a "win" for the virus, but in a way, a win for us too. Its anomalous enough though, that I feel there are some hard
questions to ask there..
Given that most tests amplify
coronavirus RNA material, not specifically this virus, it also means that measures like testing en masse and
contact tracing might have dubious efficacy. Thats without bringing in things like false positives/negatives/etc. It also doesnt address any other
vector of transmission at all. To truly do
that.. Well, Im not sure we can.
In my mind, it then becomes a question of hospital occupancy & capability. As long as we can keep that in check, with a very strong focus on it as THE
factor to determine everything else, we end up handling it with the greatest degree of efficacy possible (imo).
And, just like influenza, we can expect plenty of different mutations, etc.
The interesting part, to me, is the possible application of certain treatments in a much broader context than just SARS-CoV-2 and regardless of
mutations. There are a metric crapton of politics surrounding it, but anything that inhibits RdRPs (RNA dependent RNA polymerases) seem to have
exceedingly promising efficacy. This does include the "controversial" Hydroxy Chloroquine, but many others as well. And, HCQ (to my understanding)
only
really acts as a RdRPs inhibitor due to being a Zinc ionophore. So, testing patients Zinc levels and even providing supplements might be
absolutely critical. There are others too though, and all have shown some promise.
I have no doubt that there are other ways to treat it as well, but overall, I think that as long as we keep the medical system in check without
suppressing the natural course of building immune system familiarity ("herd immunity").. Then we really have a great foundation for success.
Hmm, DuckDuckGo-Fu Pseudo Expert, signing off
I think Im probably done with apologizing for being verbose though lol Thats like asking a bird not
to fly, methinks.