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Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.
STATEMENT OF GOVERNMENT SUPPORT
This invention was made by the Centers for Disease Control and Prevention, an agency of the United States Government. Therefore, the U.S. Government has certain rights in this invention.
FIELD OF THE DISCLOSURE
This invention relates to a newly isolated human coronavirus. More particularly, it relates to an isolated coronavirus genome, isolated coronavirus proteins, and isolated nucleic acid molecules encoding the same. The disclosure further relates to methods of detecting a severe acute respiratory syndrome-associated coronavirus and compositions comprising immunogenic coronavirus compounds.
More particularly, it relates to an isolated coronavirus genome, isolated coronavirus proteins, and isolated nucleic acid molecules encoding the same. The disclosure further relates to methods of detecting a severe acute respiratory syndrome-associated coronavirus and compositions comprising immunogenic coronavirus compounds.
Past efforts to develop rapid diagnostics and vaccines for coronavirus infection in humans have been hampered by a lack of appropriate research models and the moderate course of disease in humans. Therefore, a need for rapid diagnostic tests and vaccines exists.
originally posted by: Blaine91555
a reply to: IrateCanadian
I think the take away here should be that they patent all of them in the process of creating vaccines and studying them. Makes this a non-story. SARS is a Coronavirus, they did not create a Coronavirus from SARS. Yes, you are wrong, sorry.
originally posted by: IrateCanadian
a reply to: Chadwickus
I read that part, didn't really think it was overly necessary to share in a snippet if someone wanted to read into the Patent a bit more for themselves.
This was back in 2003 though.. So after 17 years, you would think there would be a full fledged Vaccine for it. Especially in China right now, but nothing has been said on this matter.
originally posted by: IrateCanadian
a reply to: weirdguy
I'm sure they didn't invent it. However, from what this patent describes, It seems as tho they took the first virus, "SARS" and isolated the "Coronavirus" protein/DNA from it and then patented it.
Correct me if I'm wrong.