FDA: Thousands of Deaths Associated With Drugs Given to ‘Trans’ Children

a reply to: ketsuko

Generally, when someone does not go into puberty like they are supposed, it is considered a disease for which they need medical treatment because it has all kinds of negative health effects.

Yes. You're 100% right about this, and it's also mentioned in the source article:

The recent increase in the number of gender dysphoric youths seeking drug treatments is particularly alarming to experts who see the drugs’ effects as too risky to prescribe in their current form — if at all.

Michael Laidlaw, an endocrinologist from Rocklin, California, testified before the British House of Lords on the issue of “transgender health care” in May. Laidlaw told the Register, “These drugs actually induce a known disease in previously hormonally healthy children.”

Puberty blockers, he explained, interfere with normal signals between the brain and the sex organs, thereby creating a disease state called hypogonadotropic hypogonadism in youths. “It’s a serious condition that endocrinologists would normally diagnose and treat because it interferes with development, but in [gender dysphoria] cases they’re inducing this disease state,” Laidlaw said.

And the effects go far beyond sexual development and maturity. Puberty is a time of brain development, bone development, and other important functions. All are negatively impacted with the use of puberty blockers.

a reply to: PokeyJoe

Thousands of death from trans drugs = A-OK as far as the government is concerned, 7 people die via vaping illness = BAN ALL VAPES

Amen. Really puts things in perspective, doesn't it? By showing how out of wack the world really is.

From the above linked article in the original post:
"Aside from the medical risks involved with castration drugs, the principle driving their promotion flies in the face of Catholic teaching on human sexuality."

Yes clearly, there is no agenda at work here. None at all.

This screed is not a published scientific paper. It is a collection of cherry-picked snippets spun from references that are mostly behind paywalls and in spite being presented as some revelatory and alarming information, it comes across more as concern trolling which is just as much in your face, agenda driven and shoved down your throat as the narrative from the trans activist community and I find the discourse equally as sickening from both sides of the aisle.

Don’t be misled by the title of this thread. It doesn’t mean thousands of trans children have died or will as a result of taking GnRH agonists such as Lupron and Histrelin. The article makes assumptions based on research highlighting negative outcomes primarily for natal females that are often selected for this protocol to suppress precocious puberty and that because transgender youth are also given these drugs but usually not until Tanner stage two of biological puberty has begun, the connection is being made that if we treat trans youth with these puberty blocking drugs some of them will also die or have serious health consequences. Realistically, that’s entirely possible.

But guess what though? Having a truly gender dysphoric child is a serious health consequence in and of itself and sometimes the choice to employ these protocol is the lesser of two evils nor does this article mention the consequences of non-treatment or even hint at the voices of those that have successfully undergone and benefitted from these therapies that are now happy and healthy young adults and consider the opportunity to have been able to suppress their natal puberty as life saving.

Understandably, there are concerns as a fair number of prepubescent gender dysphoric children grow out of it at puberty and puberty itself is often the mechanism that facilitates this, however, puberty is what also exacerbates it or when it manifests for some. Even critics agree that consistent gender dysphoria expressed over years persisting past the age 11 or 12 is likely to persist for life and I think these are the kids that need to be helped with these drugs in spite of the risks. I also don’t think they should be handed out like candy or treated as inconsequential.

There is no doubt in my mind additional research needs to be done in this area and the diagnostic criteria for who is eligible for these protocols needs to be reigned in despite the cries of gatekeeping from the transgender activist community. Truly and seriously gender dysphoric children exist, that’s a fact and they should be given all the help they can to live normal as possible lives but I do believe this is an extraordinarily and statistically very rare condition separate from what is very much the social driven phenomenon we’ve seen with rise in prevalence of trans youth and we need better ways to separate the wheat from the chaff, so to speak. Blanket one-size-fits-all policies from either side of the fence just doesn't work.

a reply to: Kalamitous

From the above linked article in the original post: "Aside from the medical risks involved with castration drugs, the principle driving their promotion flies in the face of Catholic teaching on human sexuality." Yes clearly, there is no agenda at work here. None at all.

As noted in the OP, some will balk at the source. If protecting kids from unnecessary harm is an "agenda," what does that say about those who refuse to protect our kids from harm?

I'll take the former every time.

This screed is not a published scientific paper. It is a collection of cherry-picked snippets spun from references that are mostly behind paywalls and in spite being presented as some revelatory and alarming information, it comes across more as concern trolling which is just as much in your face, agenda driven and shoved down your throat as the narrative from the trans activist community and I find the discourse equally as sickening from both sides of the aisle.

Concern trolling -- LOL!!!

You are correct that some of the links, and many medical studies, are behind paywalls. Hence the appropriateness of articles such as this, written by those with access to those studies to provide wider public access with summaries and explanations. None of which changes the FACT that puberty blockers are dangerous drugs, with painful and debillitating adverse effects -- including death -- for whatever reason they are prescribed.

Don’t be misled by the title of this thread. It doesn’t mean thousands of trans children have died or will as a result of taking GnRH agonists such as Lupron and Histrelin.

As noted immediately in the OP. That was my first comment on the article.

The article makes assumptions based on research highlighting negative outcomes primarily for natal females that are often selected for this protocol to suppress precocious puberty and that because transgender youth are also given these drugs but usually not until Tanner stage two of biological puberty has begun, the connection is being made that if we treat trans youth with these puberty blocking drugs some of them will also die or have serious health consequences.

Oh dear. So are you trying to tell us that some magical gender essence protects trans kids from suffering the same adverse conditions -- including DEATH -- from these drugs? Really? REALLY???

I don't even believe that YOU really think that. But it sure sounded good in your head, right?

a reply to: Boadicea

Insane..
The one I remembered in particular, they classified it as 'abuse' because one of the parents refused to let the kid get the treatment.

I admit I'm ignorant to how these people feel inside..
but I know right and wrong, and this is wrong.

a reply to: MisterSpock

At least when were all gender-less robots, this won't matter anymore.

originally posted by: Boadicea
Oh dear. So are you trying to tell us that some magical gender essence protects trans kids from suffering the same adverse conditions -- including DEATH -- from these drugs? Really? REALLY???

Please don't put words in my mouth. I'm not here to argue, just to offer a balancing point of view and food for thought. What's a "magical gender essence" anyway?

a reply to: Kalamitous

Please don't put words in my mouth.

I didn't. I didn't have to. I quoted you directly.

I'm not here to argue, just to offer a balancing point of view and food for thought.

Um... okay. You can try. But I don't see any "balance" where kids are being harmed -- often lifelong harm -- for an impossible goal.

What's a "magical gender essence" anyway?

My description of whatever unknown quality you suggests protects trans kids from the same harm these drugs cause other people....

originally posted by: Boadicea
My description of whatever unknown quality you suggests protects trans kids from the same harm these drugs cause other people....

Where exactly did I suggest such things and why are you so hostile? I believe I clearly said the potential for harm exists as a possibility and made no assertions whatsoever that trans kids were immune because they were somehow magic or special.

I actually think puberty blockers might be over-prescribed and the criteria for administering these drugs too lax. My point was that there are those can and do benefit tremendously and in properly indicated and diagnosed cases which I'll again say are extremely rare, the benefits can outweigh the risks.

Want to say the doctors are evil, but cannot bring myself to do it.

It is a violation of their OATH.

Do no harm.

Both the parents and the quacks bowing to political pressure.

originally posted by: Kalamitous
Where exactly did I suggest such things...

I shall quote you:

The article makes assumptions based on research highlighting negative outcomes primarily for natal females that are often selected for this protocol to suppress precocious puberty and that because transgender youth are also given these drugs but usually not until Tanner stage two of biological puberty has begun, the connection is being made that if we treat trans youth with these puberty blocking drugs some of them will also die or have serious health consequences.

The article assumes nothing. The article clearly describes the adverse outcomes reported to the FDA by patients and their doctors. No assumptions. The connection is being made because this how the drug affects people who take the drug.

On what basis do you suggest that trans kids are immune to the same adverse effects? You didn't like "magical gender essence," so use your own words. What do you think would protect trans kids from having the same problems with these drugs that other people have experienced? What makes trans kids special?

...and why are you so hostile?

Please don't play dumb or innocent... Does "concern troll" ring a bell???

But more to the point: The topic is the very serious dangers and lifelong damage these drugs cause to children, used experimentally and many say recklessly (including me), for limited if not non-existent benefits. You seem to be okay with that. I'm not and I'm saying it loud and proud.

I believe I clearly said the potential for harm exists as a possibility...

Actually, no, you did not. You did not specifically rule it out, but your statement did suggest that it was an "assumption" and you questioned the "connection" being made.

...and made no assertions whatsoever that trans kids were immune because they were somehow magic or special.

Yes, you did. Note again your description as "assumptions" and "connections," inferring an innate difference in trans kids that would make them exceptions.

I actually think puberty blockers might be over-prescribed and the criteria for administering these drugs too lax. My point was that there are those can and do benefit tremendously and in properly indicated and diagnosed cases which I'll again say are extremely rare, the benefits can outweigh the risks.

And I agree with all of the above -- they have been FDA approved for prostate cancer, so there must be clinical medical studies proving their efficacy. So there's that. (Though, obviously, that would tell us next to nothing about how they effect the female body.)

But I wouldn't agree they are ever appropriate for the purpose of "gender affirmation". Specifically: Beyond the transgender issues, these drugs also block the development of other necessary and vital bodily functions, including brain function. Puberty serves a greater purpose than sexual development. All of these processes must be allowed to develop and mature for the overall well being of the person. No one has the right to decide otherwise.

originally posted by: neo96

Want to say the doctors are evil, but cannot bring myself to do it.

It is a violation of their OATH.

Do no harm.

Both the parents and the quacks bowing to political pressure.

I've often wondered how a doctor could preform an abortion.
Somehow that feels like a violation of their oath as well.

Preventing conception I understand, ending conception I don't.

I'm not a pro life guy by any means but I'm not sure I could preform that duty as a doctor.

Nothing new here.

People just don't realize that prescription medication has been killing people for a long time.
Read up on a medication and you'll see even the most benign sounding ones have a chance of death, sometimes a lot
larger than you'd ever believe...

What to read something crazy

www.medicalnewstoday.com...

A clinical trial was halted when it was found that patients who use a cream containing tretonoin - a retinoid used for treating acne and other skin conditions - had a higher chance of dying, compared to patients who used a placebo

Yup, this headline could read: FDA, acne medication causes people to die.

It has nothing to do with the Trans kids, or the acne suffers, it has 100% to do with big Pharma. Apparently most people don't care.

Oh, whatever. I'll not play this game with you because it's pointless.

I happen to know a number of trans youth and young adults. Some that were suppressed and some that were not. Do you and do you believe everything you read?

Like your linked article as an example. I've gone through and followed most of the links listed. The one to the FDA doesn't even work for me and a few of the author's other comments don't seem to quite jive with the linked citations.

From your article:
"One 2016 study found that girls treated with puberty blockers had an eight-point lower IQ score than controls who did not receive the treatment."

The summary from this linked comment:

Overall, the findings suggest that GnRHa treated CPP girls do not differ in their cognitive functioning, behavioral, and social problems from the same age peers, at least, in settings that do not involve emotional processing. Although our findings with regard to emotional regulation and reactivity are inconclusive, they provide hints that CPP girls may differ in these areas from same age peers. We, therefore, suggest that future studies should to a higher degree emphasize investigation of emotional processing in a CPP population.

It was also noted:

Whereas the hormonal and auxological effects of GnRHa are well-researched, there is a lack of knowledge whether GnRHa treatment influences psychological functioning of treated children, despite the fact that prevention of psychological problems is used as one of the main reasons for treatment initiation.

(emphasis mine)

The study was from 15 natal girls and doesn't really mention IQ at all in the available abstract.
Source (full paper): Cognitive, Emotional, and Psychosocial Functioning of Girls Treated with Pharmacological Puberty Blockage for Idiopathic Central Precocious Puberty

From your article:
"This was similar to the seven-point IQ drop from 100 to 93 reported among 25 girls who took puberty blockers for two years for early puberty"

The conclusion from this study says:

This psychological evaluation did not reveal any consistent abnormalities in adopted children with early puberty. Treatment with GnRHa with or without GH did not increase emotional and behavioural problems in adopted children, nor was their self-perception decreased.

Source: Psychological assessments before and after treatment of early puberty in adopted children.

And then there's this one from your article:
"and a nine-point IQ drop in a study of a 12-year-old boy 28 months after taking the blockers." ONE BOY!

The conclusion from that study was...

Further longitudinal clinical studies comparing DTI parameters and cognition among TG adolescents under puberty suppression and age-matched controls with physiological pubertal development are needed in order to confirm the present findings and support the hypothesis on the impact of sex hormones on cognition and brain maturity during developmental stages.

Source: Brain Maturation, Cognition and Voice Pattern in a Gender Dysphoria Case under Pubertal Suppression

Furthermore, the Dr. Michael K. Laidlaw mentioned in the article doesn't have the best reputation in all this if you do a little Googling.

Taking on the Trans Pseudo-skeptics
Dr. Michael K. Laidlaw's anti-trans tirade

As with the propaganda from the trans activists, the propaganda and rhetoric from the anti-trans camp needs to be looked at with an equally critical eye and with a huge dash of salt. I can't take any of it seriously but obviously your mission to save the children and protect the womens precludes that? All I want to do is present both sides of the debate because this is a complex issue and for the people that aren't already locked into their mindset maybe to have a less one-sided view of these things.

Let's play nice, K? I'm sorry if I offended you.

a reply to: JAGStorm

Nothing new here. People just don't realize that prescription medication has been killing people for a long time.

This is true. This particular Big Pharma corporation found a new target market for their poison, the cracks and loopholes in the law to market it, and are making the most of it.

Business as usual. Health (and life) be damned.

The cult of Molech is alive and thriving.

originally posted by: Kalamitous
My point was that there are those can and do benefit tremendously and in properly indicated and diagnosed cases which I'll again say are extremely rare, the benefits can outweigh the risks.

Possibly true - but the big lie is in the attempt to include their use purely as puberty blockers in such cases. These cases simply do not and can never fall into the category of 'properly indicated and diagnosed cases' that could benefit from their use. PERIOD. End of story.

a reply to: Kalamitous

I can't take any of it seriously...

Ahem. You seem to be taking it quite seriously.

...but obviously your mission to save the children and protect the womens precludes that?

My mission, eh?

All I want to do is present both sides of the debate because this is a complex issue...

And you are quite welcome to do so, and you have.

...and for the people that aren't already locked into their mindset maybe to have a less one-sided view of these things.

Some things are never acceptable. Giving otherwise healthy children dangerous drugs with lifelong damaging effects for superficial "benefits" -- breaking what ain't broken -- is one of those things. If you want to consider that "locked into their mindset," rather than a moral and sacred duty to protect and safeguard children from unnecessary harm, okay. I find it alarming that anyone finds it acceptable to do so.

Let's play nice, K? I'm sorry if I offended you.

Hmmm... we'll see.

Absolutely apalling.
You know.. I was a tomboy growing up. I never once thought I needed to 'change genders'! I am a heterosexual female who happens to work in a male dominated field. I am very happy being female.
These kids would not even be thinking about this as an option if they were left alone to actually be children and grow up when things will become clear for them. Sorry but these deluded 'parents' should probably be taken out back and humanely dispatched. I guess at least the bloodlines will not continue. Can't believe this is where we are now either.

Wow despite calling out the source and the title in the OP but seriously it has as much objectivity as a tobacco institute article. But well sourced? Its a bit of cherry picking to be fair

Yes all drugs are dangerous and yes the hormone blocking drugs are as well. But this is clearly written as a Catholic hit piece by an author who is at best a RCC fan girl

www.ncregister.com...