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Overdose most often causes slow heart rate. Respiratory depression, low blood pressure, constricted pupils, hypothermia, brief episodes of high blood pressure,[8] drowsiness, headaches and vomiting may also occur.[9] In serious cases some of these effects may result in circulatory shock.[6] Most often overdoses occur in children who have ingested the drug.[8]
There is no antidote for tetryzoline or other similar imidazoline analogue poisoning, but the symptoms can be alleviated and with treatment, death is rare.[10]
Lana Clayton, 52, confessed to killing her husband, Stephen Clayton, after an autopsy found poisonous levels of tetrahydrozoline in his system, the York County Sheriff’s Office said Friday. Tetrahydrozoline is a chemical found in over-the-counter eye drops used to clear up eye redness.
Stephen Clayton, 64, was found dead in the couple’s home in Clover, South Carolina, on July 21. His wife held a funeral for him in their backyard earlier this month before an autopsy uncovered his cause of death, neighbors said.
She later confessed to poisoning him, authorities said, telling investigators that she placed eye drops in his drinking water for several days.