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[some reparagraphing super long paragraphs; some emphases added]
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If there has ever been one plant that “does it all”, turmeric (Curcuma longa), seems the perfect candidate. Its many health benefits and applications fill entire libraries: a search for “turmeric” on Web of Science returned 6.681 hits, and a search for “curcumin”, turmeric’s best known constituent, yielded a whopping 28.122 papers. At point of writing, the Cochrane Library holds 94 publications of controlled clinical trials involving turmeric: whoever says that knowledge of its health benefits is ficticious or anecdotal at best, has accomplished a high degree of ignorance.
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Even more so since turmeric has been used for culinary and medicinal purposes in Asia for over 6000 years (Hutchins-Wolfbrandt & Mistry 2011) – Western science today only confirms what people have naturally known and practiced for millennia (Goel et al. 2008). In the past two decades, turmeric and curcumin have been extensively studied for their therapeutic benefits as antioxidant, anti-inflammatory, cardioprotective, renoprotective, immunomodulatory, cancer chemopreventive, antidepressant, and neuroprotective agent (Pakfetrat et al. 2014, Chuengsamarn et al. 2012).
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What’s In It?
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Turmeric belongs to the ginger plant family and is native to southwest India. It contains c. 4-5% curcumin, a polyphenol and strong antioxidant which gives it its bright yellow color. Other turmeric constituents include iron, manganese, potassium, vitamins C & B6, and omega 3 & 6 fatty acids – just to name a few of over 300 compounds identified from this plant (Ravindran et al. 2009, Gupta et al. 2013). Out of all these, curcumin received most investigative attention by far.
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Turmeric’s Many Talents ~ an Overview
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[18 items listed--among them that it selectively kills cancer cells without harming healthy tissue]
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Curcumin Mechanisms of Action & Effects
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Cancer undergoes three major stages of development: tumor formation, growth, and spread. Often, drugs target any one of these stages. Curcumin, however, can interfere with all three – one reason why some deem it as little prone to resistance development by tumors: curcumin can always take another route (see Ravindran et al. 2009). In animal models, curcumin induced cell death (apoptosis & autophagy) in cancer cells and also inhibited tumor growth, invasion, and in vivo metastasis (Ravindran et al. 2009, Gupta et al. 2013). In vivo animal studies also clearly suggest curcumin’s anticancer potential when administered either alone or in combination with currently employed chemotherapeutic agents or radiation (Goel et al. 2008). This wealth of positive results in animals spurred a host of human studies, including dozens of clinical trials.
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Curcumin blocks the expression of growth and metastasis promoting genes (Goel et al. 2008) and so inhibits angiogenesis (connecting the tumor to blood vessels) – a process crucial to tumor growth and spread. It also sensitizes cancer cells to conventional treatment methods (chemotherapy and radiation) (Hutchins-Wolfbrandt & Mistry 2011). One paper reported supplementation with eight grams curcumin per day in combination with the drug gemcitabine as safe and well tolerated in pancreatic cancer patients (Gupta et al. 2013), as were up to two grams curcumin daily in a phase I clinical trial that combined FOLFOX chemotherapy with curcumin (James et al. 2015). Curcumin by itself also gave significantly improved results when tested on patient-derived colorectal liver metastase cells and performed better than FOLFOX and 5-FU (another cancer drug) in some patients (their isolated cells in culture) (James et al. 2015).
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originally posted by: BO XIAN
It has clearly been helpful in my close friend's self-treated recovery from her 2nd bout of cancer in about 30 years. It was not the only thing she used, however.
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originally posted by: BO XIAN
a reply to: 3danimator2014
I try to save most of my responses for folks who demonstrate a shred of interest in fair-minded dialogue.
I trust my friend's assessments.
originally posted by: BO XIAN
a reply to: BO XIAN
Folks, there are enough quality scientific studies done on Turmeric . . . you don't have to be at the mercy of those unwilling to see the benefits. Check the data out.
As history has proven . . . science CAN be the last to admit truth.
Thankfully, in this case, there's plenty of science on the side of the effectiveness of turmeric to help a long list of health issues.
Cheers to that!
originally posted by: ParanoidCovKid
You pay tax for free energy.....WTF!!
originally posted by: 3danimator2014
I guess one question re: cancer benefits of turmeric is whether India has lower numbers of cases. I'm in bed now otherwise I would look..
originally posted by: hopenotfeariswhatweneed
originally posted by: 3danimator2014
I guess one question re: cancer benefits of turmeric is whether India has lower numbers of cases. I'm in bed now otherwise I would look..
Even if there were only a placebo effect is that such a bad thing?....no where do I see it stated as cure ...all it seems have is many health benefits including helping chemo treatments...
Personally if I were ill I would be looking into and trying everything that was at my disposal......
originally posted by: BO XIAN
a reply to: Rezlooper
THANKS BIG.
Yeah, you noticed the same phenomenon. One might think that they could live and let live . . . or state their opinions in reasonable tones and move on. But nooooooooooooo . . . there's all this emotionally hostile diatribe and arrogance to fling far and wide in the process. Underwhelming.
Abstract:
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Of particular interest for cancer prevention is the role of turmeric (curcumin), an ingredient in common Indian curry spice. Researchers have also investigated cumin, chilies, kalakhar, Amrita Bindu, and various plant seeds for their apparent cancer preventive properties. . . . there is an increasing need to develop cancer prevention programs responsive to the unique diets and cultural practices of the people of India.