Spanish Priest with Ebola Has Died

The Spanish priest has died.
He had been treated with ZMapp

(CNN) -- Miguel Pajares, a Spanish priest who was infected with Ebola, died Tuesday morning from the virus, the Carlos III hospital in Madrid said. MORE FROM KSPR.COM URGENT - Ebola WHO medical ethics Ebola death toll tops 1,000 amid drug debate

Source

CNN is the original source of this.

originally posted by: violet
The Spanish priest has died.
He had been treated with ZMapp

(CNN) -- Miguel Pajares, a Spanish priest who was infected with Ebola, died Tuesday morning from the virus, the Carlos III hospital in Madrid said. MORE FROM KSPR.COM URGENT - Ebola WHO medical ethics Ebola death toll tops 1,000 amid drug debate

Source

CNN is the original source of this.

May god reward him for his efforts.

Ameen

Miguel Pajares was 75.

This experimental drug did not work on him.

"It is confirmed. He died at 9:28 am," said a spokeswoman for Spain's La Paz-Carlos III hospital.

The priest had been treated with ZMapp, she said. The medicine arrived at Madrid's La Paz-Carlos III hospital on Saturday after Spain's drug safety agency exceptionally cleared its import to treat the deadly disease.

Ebola has now claimed four lives in 10 days among the staff of the same Saint Joseph Hospital in Monrovia, which has since been shuttered.

Link

Four staff dead in that hospital so far.
Why are medical professionals contracting this virus as often as they have?
I keep hearing about how difficult it is to contract this virus, yet these people that are educated about the means of transmission are getting it.

a reply to: violet

The article I read stated there was no confirmation if the experimental drug Zmapp was ever administered to him. Let me find the article.

Almost seems like they're talking out of both sides of their mouths:

Pajares died Tuesday at Carlos III Hospital, the hospital and his order said. The hospital would not confirm that he had been treated with the drug, but his order said earlier that he would be.

He is one of only three Ebola patients thought to have received the experimental drug. The others are two Americans evacuated to Atlanta.

Source

a reply to: Rosinitiate
Fox News says that he did receive the Zmapp treatment.

Spanish authorities said a 75-year-old Spanish priest who contracted Ebola in Liberia had died. The government had announced on Sunday that Miguel Pajares, the first European infected by the strain, would also be treated with ZMapp manufactured by California-based Mapp Biopharmaceutical. In addition to Pajares, ZMapp has already been administered to two U.S. aid workers. The U.S. citizens are now in a hospital in Atlanta, Georgia, after being medically evacuated and have shown some signs of improvement.

It is a little bit sketchy, but the way I read it, he got the treatment.

a reply to: butcherguy

There is no confirmation in there either, but yes it does bring one to that conclusion. I am sure they are being vague intentionally, after all, Liberia just received an entire shipment exhausting supplies of Zmapp.

But again on CNN:

The Spanish missionary priest, 75-year-old Miguel Parajes, died Tuesday in a Madrid hospital, the hospital and his order said. The hospital would not confirm that he had been treated with the drug, but his order and Spain's Health Ministry said earlier that he would be.

but here's a little more doublespeak:

Two Americans and reportedly a Spanish priest have gotten an experimental Ebola treatment never tested in humans and two more Ebola treatments were said to be on their way to treat two doctors in Liberia. ZMapp, a cocktail of monoclonal antibodies, was developed in part at the Canadian National Microbiology Laboratory in Winnipeg.

www.cbc.ca...

In the same breath they say it CAN be tested. Don't jitter the stocks.

originally posted by: butcherguy
Four staff dead in that hospital so far.
Why are medical professionals contracting this virus as often as they have?
I keep hearing about how difficult it is to contract this virus, yet these people that are educated about the means of transmission are getting it.

Its because they are spending 20 odd hours a day elbow deep in infected fluids understaffed with poor equipment.

There are no shiny hospitals with modern equipment and relief staff.

a reply to: Rosinitiate

Even with the best treatment there will be a cut off point when your too far gone that it will make a difference. If he was suffering multi organ failure then even if they had begun to clear the virus the after-effects could have bee too severe.

That's if Zmap even works and the two American were not just in 45% that survive anyway.

That's why WHO and CDC are not trying to play this up as a miracle cure yet, it could very well not work.

originally posted by: crazyewok
a reply to: Rosinitiate


That's why WHO and CDC are not trying to play this up as a miracle cure yet, it could very well not work.

Isn't that moot anyways? After all Liberia received a shipment this morning (the last) so there would/should be a better indicator in the near term.

Glaxo was also permitted to start clinical trial for theirs perhaps as early as september. TKMR is already fast tracked by special waiver to a "partial hold" allowing for clinical trials. The timing of course is remarkable.

a reply to: Rosinitiate

Thats the thing though Liberia got a shipment it is still in trial. We wont know if it truly works until its given to more people.

originally posted by: crazyewok
a reply to: Rosinitiate

Thats the thing though Liberia got a shipment it is still in trial. We wont know if it truly works until its given to more people.

That's kind of the point though. It's not as if they will sit on it. They received the shipment with approval from from the US and WHO. However, since that was reported both the US administration and WHO has backed off from such claims:

The World Health Organization, or WHO, also denied earlier reports that it had authorized the use of ZMapp, the experimental Ebola drug, in Liberia, the report added.

"We were not involved in transferring the serum and we will not be involved in any future transfers of it," Gregory Hartl, a WHO spokesman, said according to AP. "WHO doesn't have any role in handing out the serum or any other experimental medicines."

but:

The approval from the U.S. for access to the experimental drug, very little quantities of which are currently available because it's not ready for large-scale commercial use, is in response to a request made by Liberian President Ellen Johnson Sirleaf on Friday, asking for the drug to be used on infected Liberian doctors.

“The White House and the United States Food and Drug Administration have approved the request for sample doses of experimental Serum to treat Liberian doctors who are currently infected with the deadly Ebola virus disease,” the Liberian government said, in a statement Monday, adding: “The experimental drugs are to be brought in the country by a representative of the U.S. Government later this week.”

The statement from the Liberian government also said that Margaret Chan, executive director of the World Health Organization, has also approved shipping additional doses of the drug to treat the affected doctors.

Adding Source

The Vatican will probably make him a saint now, Saint Pajares, the patron saint of Ebola sufferers.

originally posted by: crazyewok

originally posted by: butcherguy
Four staff dead in that hospital so far.
Why are medical professionals contracting this virus as often as they have?
I keep hearing about how difficult it is to contract this virus, yet these people that are educated about the means of transmission are getting it.

Its because they are spending 20 odd hours a day elbow deep in infected fluids understaffed with poor equipment.

There are no shiny hospitals with modern equipment and relief staff.

Ah, so they are committing suicide by working without basic PPE.
Okay.

originally posted by: butcherguy

Ah, so they are committing suicide by working without basic PPE.
Okay.

Basically yeah.

It just not practical to work in those cat 4 space suits all day in high tropical temperatures in areas were electricity spends more time off than on.

Your basically reduced to using cat 3 gear and even then there is a shortage.

Read here
for a idea of the condition the doctors and nurses are facing out there.

These are real hero's putting there life's on the line for others.

a reply to: crazyewok
Like I said, I keep hearing that it very difficult to contract the virus.

They should need a surgical mask, gloves, a gown and a pair of specs....

Or this virus isn't that hard to catch.

originally posted by: butcherguy
a reply to: crazyewok
Like I said, I keep hearing that it very difficult to contract the virus.

They should need a surgical mask, gloves, a gown and a pair of specs....

Or this virus isn't that hard to catch.

If your just passing through then sure.

But the doctors and nurses are in constant close contact with very sick people. If someone vomits on you ect then thats the risk.

To but it another way if you walk through a Ebola ward with basic PPE then you will be fine, even without PPE you will likely be ok as long as you don't touch anything. Start touching the sick and there fluids THEN your at risk.

a reply to: butcherguy

There is more about this virus they do not know than what they do with 100% certainty. Add to that, of the 4 subtypes of Ebola (5 to count an oddball listing not everyone shows) We had to get "lucky" with this one being the most virulent of the bunch. Ebola Zaire.

Running average case fatality rate is 55% right now, with the CDC website updates showing "up to" 75% in Guinea.

The World Health Organization has estimated the mortality of the current outbreak of EVD in West Africa to be approximately 55%, but appears to be as high as 75% in Guinea.

Source: Centers for Disease Control - Atlanta

It's easier to get than the people making a living of playing it down right now would have anyone believe...but nothing remotely like the common cold or flu for contagion factor. Ebola Zaire *IS* strongly suspected of crossing the air gap to transmit in previous outbreaks though. That isn't airborne transmission..and the two are very very different things. (The diff between walk away and run like your hair is on fire). It's a bad bug and one to never take lightly.

a reply to: crazyewok
I am still curious as to why a person would need a positive pressure suit (Cat 4) if the virus spreads through body fluids.
This disease doesn't spread easily, so a person should be fine with a barrier to prevent fluids from touching your skin or mucous membranes.

originally posted by: butcherguy
a reply to: crazyewok
I am still curious as to why a person would need a positive pressure suit (Cat 4) if the virus spreads through body fluids.
This disease doesn't spread easily, so a person should be fine with a barrier to prevent fluids from touching your skin or mucous membranes.

Your right.

But again this breaks downs in these country's as even that is difficult to maintain. Did you read the article ? There lack very basic equipment so even simple barrier techniques are difficult to maintain. Its all well and good you saying wear a mask gown and glove and they will be fine, but in theses places they may not even have that! In fact a news report I read a few days back said a hospital in Liberia ran out of gloves!

Then you have decontamination. You cant just take those gowns and gloves off, the fluids could transfer so you have decontaminate them. Which again is easier said than done in a area were basic plumbing is a on and off thing.