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A chemical found in many "BPA free" consumer products, known as bisphenol S (BPS), is just as potent as bisphenol A (BPA) in altering brain development and causing hyperactive behavior, an animal study finds. The results were presented Sunday at the joint meeting of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014 in Chicago.
BPA has been linked to a wide range of hormone disorders, such as obesity, reproductive cancers and, recently, hyperactivity in children born to women exposed to high levels of this substance during the second trimester of pregnancy. Now, this research in fish found that exposure to BPS, a bisphenol compound, led to hyperactive offspring, just as BPA did.
"BPS, termed the safe alternative to BPA, may be equally as harmful to developing brains," said the study's senior investigator, Deborah Kurrasch, PhD, from Canada's University of Calgary. "Society must place increased pressure on decision makers to remove all bisphenol compounds from manufacturing processes."
The study investigated the effects of BPA and BPS on brain development in zebrafish. This fish is developmentally similar to humans, but the embryo grows externally, enabling researchers to see development of the offspring.
In the years since research evidence first showed many potentially damaging health effects of the industrial chemical BPA, some manufacturers have switched to its chemical cousin, BPS, to make hard plastics and other products that they call BPA free, said the study's lead investigator, Hong-Sheng Wang, PhD, from the University of Cincinnati.
Although some BPA-free products contain no bisphenols, Wang said, "BPS is one of the substitutes used in BPA-free products. There is implied safety in BPA-free products. The thing is, the BPA analogs -- and BPS is one of them -- have not been tested for safety in humans."
BPA is an endocrine (hormone) disrupter that can interfere with the actions of native estrogen and other hormones, but it is not clear whether BPS also is disrupts hormones.
In what Wang called "one of the first assessments of BPS' effect in mammalian primary cells or organs," he and his co-workers tested an environmentally relevant dose of BPS in the hearts of approximately 50 rats. The 1-nanomolar dose was in the range of BPS found in human urine samples in a study by other authors.
In the current study, the investigators perfused, or flowed, BPS through the arteries of each animal's pumping heart, after stimulating the heart with the hormone catecholamine to mimic stress. For a control group, 30 rat hearts received only catecholamine and no BPS.
Exposure to BPS rapidly increased the heart rate of female rats and under the stress condition led to arrhythmias -- heart rhythm abnormalities -- far greater than in the control rats that did not receive BPS, Wang reported. Electocardiograms demonstrated that BPS caused extra heartbeats and a racing heartbeat, also known as ventricular tachycardia. In male rats, BPS reportedly did not have this rapid impact on the heart.
originally posted by: eisegesis
a reply to: knoledgeispower
Thanks for pointing this out. Its the same mind [snipped] they tried to pull on us with diet food and sugar substitutes.
Use glass, throw out your microwave, buy a toaster oven. The increase in your electricity bill is worth your overall well being, especially for newborns.
S+F
Laboratory tests commissioned by the Environmental Working Group have detected bisphenol A (BPA), a plastic component and synthetic estrogen, in umbilical cord blood of American infants.
Nine of 10 randomly selected samples of cord blood tested positive for BPA, an industrial petrochemical.
BPA has been implicated in a lengthening list of serious chronic disorders, including cancer, cognitive and behavioral impairments, endocrine system disruption, reproductive and cardiovascular system abnormalities, diabetes, asthma and obesity.
In all, the tests found as many as 232 chemicals in the 10 newborns, all of minority descent. The cord blood study has produced hard new evidence that American children are being exposed, beginning in the womb, to complex mixtures of dangerous substances that may have lifelong consequences.
A prior study by EWG found that blood samples from newborns contained an average of 287 toxins, including mercury, fire retardants, pesticides, and Teflon chemicals.
Of the 287 chemicals EWG detected in umbilical cord blood, it’s known that:
180 cause cancer in humans or animals
217 are toxic to your brain and nervous system
208 cause birth defects or abnormal development in animal tests
originally posted by: Lil Drummerboy
a reply to: knoledgeispower
first,, love the tie..lol
and yes, heating anything in plastics..is bad
hate to say it but, it was known a long time ago, the estrogen mimicking component was present in all plastics.
originally posted by: knoledgeispower
originally posted by: Lil Drummerboy
a reply to: knoledgeispower
first,, love the tie..lol
and yes, heating anything in plastics..is bad
hate to say it but, it was known a long time ago, the estrogen mimicking component was present in all plastics.
I know but BPS was deemed a safe substitute for BPA
originally posted by: rickymouse
You can't avoid these endocrine disruptors. They are in everything. It may not be in plastic when you get it, but it was probably in plastic for a while during processing or transportation. We have become obsessed with plastic.
I read that BPA is not the only bad chemical in plastic, but they want us to think it is. There are a couple of more bad chemicals almost as bad as BPA that we hear little about. That is the way they work, they pick on one chemical to target. The stuff they spray on our food to keep it looking fresh longer is probably a lot worse.
originally posted by: subtopia
Our species has proven to be very resilient to pollution. The fundamental reality is out of seven billion of us there will be enough of us that mutate and adapt to continue until we advance enough to fix the problems caused by our industrial advancements.
Those who live on the rubbish dumps of the present will be the genetic leaders of the future....