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Researchers might have found the Holy Grail in the war against cancer, a miracle drug that has killed every kind of cancer tumor it has come in contact with, the New York Post reported.
The drug works by blocking a protein called CD47 that is essentially a "do not eat" signal to the body's immune system, according to Science magazine.
This protein is produced in healthy blood cells, but researchers at Stanford University found that cancer cells produced an inordinate amount of the protein thus tricking the immune system into not destroying the harmful cells.
With this observation in mind, the researchers built an antibody that blocked cancer's CD47 so that the body's immune system attacked the dangerous cells.
"What we've shown is that CD47 isn't just important on leukemias and lymphomas," says Weissman. "It's on every single human primary tumor that we tested." Moreover, Weissman's lab found that cancer cells always had higher levels of CD47 than did healthy cells. How much CD47 a tumor made could predict the survival odds of a patient.
To determine whether blocking CD47 was beneficial, the scientists exposed tumor cells to macrophages, a type of immune cell, and anti-CD47 molecules in petri dishes. Without the drug, the macrophages ignored the cancerous cells. But when the anti-CD47 was present, the macrophages engulfed and destroyed cancer cells from all tumor types.
CD47 is a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[1] Isoform 2 and 4 are the most abundant. Other than thrombospondin, CD47 also binds CD172a. CD47 deficient mice have been generated. Their reported phenotype is a defect in cellular migration of the CD172a expressing cells, suggesting that CD47 to CD172a interactions are necessary for the proper distribution of these cell types.
Originally posted by Blazer
Yet another in an extremely long line of cures, free energy devices, etc that will change the world and yet are swept under the rug and never heard from again.
Isn't it interesting how everyone one of these stories, there is zero follow-up. This miracle treatment will never be developed, and months and even years from now the very people excited about it today (including yourself) will not ask anyone else "hey what happened to that miracle cure"? Very soon you won't care, or you will be distracted by the next big thing which will also never come to fruition.
Originally posted by Blazer
Yet another in an extremely long line of cures, free energy devices, etc that will change the world and yet are swept under the rug and never heard from again.
Isn't it interesting how everyone one of these stories, there is zero follow-up. This miracle treatment will never be developed, and months and even years from now the very people excited about it today (including yourself) will not ask anyone else "hey what happened to that miracle cure"? Very soon you won't care, or you will be distracted by the next big thing which will also never come to fruition.
Originally posted by davesmart
Originally posted by Blazer
Yet another in an extremely long line of cures, free energy devices, etc that will change the world and yet are swept under the rug and never heard from again.
Isn't it interesting how everyone one of these stories, there is zero follow-up. This miracle treatment will never be developed, and months and even years from now the very people excited about it today (including yourself) will not ask anyone else "hey what happened to that miracle cure"? Very soon you won't care, or you will be distracted by the next big thing which will also never come to fruition.
Hya
I very much agree though..
Prevention is better than the cure
Originally posted by ForwardDrift
Originally posted by davesmart
Originally posted by Blazer
Yet another in an extremely long line of cures, free energy devices, etc that will change the world and yet are swept under the rug and never heard from again.
Isn't it interesting how everyone one of these stories, there is zero follow-up. This miracle treatment will never be developed, and months and even years from now the very people excited about it today (including yourself) will not ask anyone else "hey what happened to that miracle cure"? Very soon you won't care, or you will be distracted by the next big thing which will also never come to fruition.
Hya
I very much agree though..
Prevention is better than the cure
Generally true, but not everything can be prevented--In this particular case, not every cancer can be attributed to poor/unhealthy lifestyle. My mother had kidney cancer and lived an extremely healthy life-style. So some technological responses are engendered out of the need to respond to things that aren't always predictable and preventable.edit on 4-4-2013 by ForwardDrift because: (no reason given)
Originally posted by Night Star
Just want to say that I wish your Dad all the best. I will keep him in my thoughts and prayers. I have battled cancer myself.
Originally posted by davesmart
reply to post by PhoenixOD
Hi op excellent news.
How long will it be before it has a mind of its own and start attacking other cells.
You know as well as i that these claims come to fruit several times a year, when most of us know the cancer killer...
Bicarbonate of Soda
ETA: my dad died a horrible death of stomach cancer 10 yrs ago, I do understand op.
edit on 2012/06/12 by davesmart because: (no reason given)
Originally posted by the_philth
Consider this scientist dead within a few weeks ---- probably in a weird jogging accident or reports that he died in his sleep... you know... died of natural causes!