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InFriNiTee
Big-pharma makers of diabetes products are on record saying that a cure wouldn't be profitable enough for them. I am willing to bet they have bought the rights on multiple ways of curing the illness, only to shelve those ideas while maintaining the rights.
The world needs a cure for diabetes, and one that doesn't require a laboratory or surgery. The world needs a cure that can be taken at home. I know of lots of herbs and supplements that reduce the need for even type 1 diabetics to take insulin. I know from the bottom of my heart that there is a cure out there somewhere. I've been searching for much of my life, and haven't found it yet.
We need a rogue doctor on ATS to tell us the secret cure(s)! If there was one out there with the guts to do it, and if they had discovered something that truly works...
edit on 10/16/2013 by InFriNiTee because: (no reason given)
The term antigen originally came from ANTIbody GENerator (see section History).
The antigen may originate from within the body or from the external environment. "Self" antigens are usually well tolerated by the immune system, which has been educated to non-reactivity against the structures present inside the body under the physiological conditions. "Non-self" antigens can be identified as invaders from the outside world or modified/harmful substances present under the distressed conditions in the body and only these are supposed to be attacked by the immune system. In other words, the immune system will try to destroy or neutralize any antigen that has been recognized as a foreign substance and /or signal of harmed tissues.
soficrow
reply to post by hiddencode
I think that PLOS article is a GREAT find - F&S just for that - and the Self-Organized Criticality Theory of Autoimmunity seems right to me. Just so you know, vaccines are NOT the only source of antigens - and our fubarred environment s now shock full of antigens.
The term antigen originally came from ANTIbody GENerator (see section History).
The antigen may originate from within the body or from the external environment. "Self" antigens are usually well tolerated by the immune system, which has been educated to non-reactivity against the structures present inside the body under the physiological conditions. "Non-self" antigens can be identified as invaders from the outside world or modified/harmful substances present under the distressed conditions in the body and only these are supposed to be attacked by the immune system. In other words, the immune system will try to destroy or neutralize any antigen that has been recognized as a foreign substance and /or signal of harmed tissues.
OneisOne
reply to post by hiddencode
While it's not something that will reverse type 1, there are drugs out there that stops the body's attack on the beta cells. They will never make it to market because Big Pharma will never admit to how effective they are. I know from personal experience because I precipitated one of the studies.
During the course of the study my insulin needs dropped, as did my blood glucose. It was pretty amazing. Then before the study finished it was canceled as being "ineffective" and I was informed I did not receive the drug (double blind study). To this day I believe I did receive it but my record was changed to reflect the "ineffective" conclusion.
Despite the official record, I'm glad I participated in the study. It was an interesting experience!
dollukka
Even this study looks fancy.. We have two countries Finland which population is a little over 5 million people and Russia which population is 142 million, we compare them and see difference.. of course ( and btw where in that map shows Finland .. there is Russia not Finland.. hello ??? )
Pretty much same as US which has 300 million population to be compared to half of Madagaskar ( approx 10 million people )
Something just isn´t right
What comes to gene mutation which causes type 1. In our little family i don´t have that gene, Hubby does ( but have not type 1.. yet ) Hubby´s aunt has mutation and has type 1 and lives in Germany also her daughter has the gene but not yet type 1.edit on 16-10-2013 by dollukka because: (no reason given)
dollukka
reply to post by OneisOne
Would like to know more of this study ! It is said that if they could protect betacells and pancreas from immune attacks, new working cells will reform in pancreas. They used to think that pancreas is totally destroyed and dead but studies have shown that there is hope.
Diabetes at 15 Months Old:
"My daughter, age 15 months, received her first MMR vaccine at a routine well-baby check-up. Prior to receiving the vaccine she had no health problems other than an occasional cold. Three weeks later she was diagnosed with Type I diabetes.
Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas.
"I couldn't believe it," said Dr. Michael Salter, a pain expert at the Hospital for Sick Children and one of the scientists. "Mice with diabetes suddenly didn't have diabetes any more."
The researchers caution they have yet to confirm their findings in people, but say they expect results from human studies within a year or so. Any treatment that may emerge to help at least some patients would likely be years away from hitting the market.
dollukka
reply to post by hiddencode
I will mention this study and HIB connection to our doctor who is also biomed expert and researcher, and see what she thinks of this
reply to post by OneisOne
Would like to know more of this study ! It is said that if they could protect betacells and pancreas from immune attacks, new working cells will reform in pancreas. They used to think that pancreas is totally destroyed and dead but studies have shown that there is hope.
OneisOne
dollukka
reply to post by OneisOne
Would like to know more of this study ! It is said that if they could protect betacells and pancreas from immune attacks, new working cells will reform in pancreas. They used to think that pancreas is totally destroyed and dead but studies have shown that there is hope.
I participated in the study Defend2, the drug was Otelixizumab.
The best article I can find about the drug & T1D studies: Otelixizumab in the Treatment of Type 1 Diabetes Mellitus
I know the drug is currently being studied for rheumatoid arthritis. And while I was in the Defend2 study I was told participants with psoriasis reported a reduction in symptoms.
InFriNiTee
There are thousands of stories like the one here from nvic.org:
Case Reports to NVIC of Diabetes Following MMR Shots
Diabetes at 15 Months Old:
"My daughter, age 15 months, received her first MMR vaccine at a routine well-baby check-up. Prior to receiving the vaccine she had no health problems other than an occasional cold. Three weeks later she was diagnosed with Type I diabetes.
I know that mouse studies don't always translate to human studies. What gets me is what Dr. Salter found a few years ago with diabetic mice:
www.canada.com...
Diabetic mice became healthy virtually overnight after researchers injected a substance to counteract the effect of malfunctioning pain neurons in the pancreas.
"I couldn't believe it," said Dr. Michael Salter, a pain expert at the Hospital for Sick Children and one of the scientists. "Mice with diabetes suddenly didn't have diabetes any more."
The researchers caution they have yet to confirm their findings in people, but say they expect results from human studies within a year or so. Any treatment that may emerge to help at least some patients would likely be years away from hitting the market.
If you read in the article I quoted above, they said that there were going to be upcoming human clinical trials. I have searched and searched for quite some time to see if those "human" trials ever got started, and I cannot seem to find anything about that. If anyone ever does find out about human trials of this treatment, please share it on ATS!
The reason I mention this is because I wonder if the treatment would be "too effective" on humans. I have even fantasized about how a person would go about using an endoscope injector (with someone rogue who was trained) to inject capsacin into the pancreas, just to see if it works. The thing is it might hurt a little bit at first, but would it cure the disease? I would take that before insulin injections and all the other pokes pricks and hospital trips!
The big thing though for that one is: WHAT HAPPENED to the HUMAN clinical trials??? This was discovered in 2006, and if it worked on humans capsacin is CHEAP! I just doubt the FDA would ever approve it...
InFriNiTee
I found a fantastic video from Dr. Lawrence Rosenberg M.D. Ph.d. McGill University. They are in phase II of clinical trials for their new anti-diabetic drug Exulin. I hope their trials work out well, and the FDA approves it if it works. Just the same as all the other companies hoping to do this.
Here is a video showing what Exsulin is trying to do. I feel for the little Eli and the 2190 shots per year. I can relate, as he's getting it about when I did:
The reason why the second video is important is because Dr. Rosenburg points out that the pancreas can be regenerated, and this has been known about for a long time. They just haven't found a way to make it permanent. Their product is another rDNA origin product (GMO, like modern insulin analogs). I don't particularly care, if it actually works. Sorry, I couldn't find the video on Youtube. It's 45 minutes, but Dr. Rosenburg makes some very good points which make me think there are a lot of ways to potentially cure diabetes:
INGAP/Exsulin Presentation March 31, 2009 (45 minutes)
The Exsulin product works by supplying a polypeptide called INGAP which restores the beta cells in animals that have been given diabetes. They have tested it on human pre-clinical trials and they say it is the cure for diabetes.
My only request to the lawmakers is:
To allow the states to allow medical clinics to be set up for fast-track approval of medical treatments that are clinically proven, and to also allow the states to individually choose to exclude the FDA from having any jurisdiction whatsoever. If a company can show a safe and effective cure, then they can sell it in a state that wants to approve it. In a perfect world...edit on 10/17/2013 by InFriNiTee because: (no reason given)