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Originally posted by r2d246
reply to post by Drala
Couple thoughts. If you get a hot particulate in the lung, like your breath it in, could that start your whooping cough or am I like way way off base??
Drala. I'm so sorry your Brother has been diagnosed with cancer. 27, he's so young, has youth on his side in his uphill battle.
Originally posted by Domo1
reply to post by Destinyone
Drala. I'm so sorry your Brother has been diagnosed with cancer. 27, he's so young, has youth on his side in his uphill battle.
I second that. For what its worth I'll say a little prayer. I hope your brother beats the crap out of that C word.
B. pertussis has the ability to inhibit the function of the host's immune system. The toxin, known as pertussis toxin (or PTx), inhibits G protein coupling that regulates an adenylate cyclase-mediated conversion of ATP to cyclic AMP, in this case (cyaA). The end result is phagocytes convert too much ATP to cyclic AMP, which can cause disturbances in cellular signaling mechanisms, and prevent phagocytes from correctly responding to an infection. PTx, formerly known as lymphocytosis-promoting factor, causes a decrease in the entry of lymphocytes into lymph nodes, which can lead to a condition known as lymphocytosis, with a complete lymphocyte count over of 4000/μL in adults or over 8000/μL in children. The infection occurs mostly in children under the age of one when they are unimmunized, or children with faded immunity, normally around the ages 11 through 18. The signs and symptoms are similar to a common cold: runny nose, sneezing, mild cough, and low-grade fever. The patient becomes most contagious during the catarrhal stage of infection, normally two weeks after the coughing begins. It may become airborne when the person coughs, sneezes, or laughs. Pertussis vaccine is part of the diphtheria, tetanus, and acellular pertussis (DTaP) immunization. The paroxysmal cough precedes a crowing inspiratory sound characteristic of pertussis. After a spell, the patient might make a “whooping” sound when breathing in, or may vomit. Adults have milder symptoms, such as prolonged coughing without the “whoop”. Infants less than six months also may not have the typical whoop. A coughing spell may last a minute or more, producing cyanosis, apnoea and seizures. However, when not in a coughing fit, the patient does not experience trouble breathing. This is because B. pertussis inhibits the immune response, so very little mucus is generated in the lungs. A prolonged cough may be irritating and sometimes a disabling cough may go undiagnosed in adults for many months.
Originally posted by Domo1
reply to post by Destinyone
Drala. I'm so sorry your Brother has been diagnosed with cancer. 27, he's so young, has youth on his side in his uphill battle.
I second that. For what its worth I'll say a little prayer. I hope your brother beats the crap out of that C word.