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Adeno-associated virus type 2 (AAV2) is a virus that regularly infects humans but causes no disease. Past studies by the same researchers show that it promotes tumor cell death in cervical cancer cells infected with human papillomavirus. Researchers used an unaltered, naturally occurring version of AAV2 on human breast cancer cells.
"We can see the virus is killing the cancer cells, but how is it doing it?" Alam said. "If we can determine which viral genes are being used, we may be able to introduce those genes into a therapeutic. If we can determine which pathways the virus is triggering, we can then screen new drugs that target those pathways. Or we may simply be able to use the virus itself."
Research needs to be completed to learn how AAV2 is killing cancer cells and which of its proteins are activating the death pathways.
AAV2 does not affect healthy cells. However, if AAV2 were used in humans, the potential exists that the body's immune system would fight to remove it from the body. Therefore, by learning how AAV2 targets the death pathways, researchers potentially can find ways to treat the cancer without using the actual virus.
100 percent of the cancer cells are destroyed by the virus within seven days, with the majority of the cell death proteins activated on the fifth day.
In another study, a fourth breast cancer derived cell line, which is the most aggressive, required three weeks to undergo cell death
According to Meyers, the cellular myc gene seems to be involved. While usually associated with cell proliferation, myc is a protein also known to promote cell death
In ongoing studies, the Penn State researchers have also shown AAV2 can kill cells derived from prostate cancer, methoselioma, squamous cell carcinoma, and melanoma
Originally posted by illuminatislave
This will never see the light of day. There's too much money to be made in "treating" cancer instead of eliminating it from the planet completely.
Brought to you by the same compassionate folks that are causing the "drug shortage" of meds for cancer patients.
However, if AAV2 were used in humans, the potential exists that the body's immune system would fight to remove it from the body.
Therefore, by learning how AAV2 targets the death pathways, researchers potentially can find ways to treat the cancer without using the actual virus.
Its not just women that can suffer from breast cancer
if AAV2 were used in humans, the potential exists that the body's immune system would fight to remove it from the body.
...by learning how AAV2 targets the death pathways, researchers potentially can find ways to treat the cancer without using the actual virus.