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DEET is absorbed through the skin, so it is important to use as low a concentration as is effective (10% or less for children) and as small an amount as is necessary. Up to a certain point, protection against insects increases with higher DEET concentration, but even low concentrations will protect against most bites. Some people experience irritation or an allergic reaction to DEET-containing products. DEET is toxic and potentially fatal if swallowed, so care should be taken to avoid applying repellent to hands or face or anything a child might put in the mouth. DEET should not be applied to areas with cuts or sores or around the eyes, since permanent eye damage can result from contact. High doses or long-term exposure to DEET have been associated with neurological damage. DEET can damage some plastics and synthetic fabrics, such as nylon and acetate, so be careful not to damage clothing or camping equipment.