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In the study just published in the journal Genome Research, scientists mapped the points at which vitamin D interacts with our DNA and identified over 200 genes directly influenced by vitamin D. The study scientists used new DNA sequencing technology to create a map of vitamin D receptor binding. The vitamin D receptor is a protein which is activated by vitamin D. The protein attaches itself to DNA and influences what proteins are made from our genetic code. The researchers found 2,776 binding sites for the vitamin D receptor along the length of the human genome. The binding sites were found to be unusually concentrated near a number of genes which have been associated with susceptibility to autoimmune conditions such as MS, Crohn’s disease, lupus and rheumatoid arthritis, as well as to cancers such as chronic lymphocytic leukemia and colorectal cancer. The study also demonstrated that vitamin D had a significant effect on the activity of 229 genes including IRF8, which has been previously associated with MS, and PTPN2, which has been associated with Crohn’s disease and type 1 diabetes.
Another study author, Sreeram Ramagopalan, added "Considerations of vitamin D supplementation as a preventative measure for these diseases are strongly warranted.” A wealth of studies on vitamin D have reported many benefits of the esesential vitamin, including: • It is crucial for the absorption and metabolism of calcium and phosphorous, which have various functions, especially the maintenance of healthy bones. • It is an immune system regulator. • It may be an important way to arm the immune system against disorders like the common cold. • It may reduce the risk of developing multiple sclerosis. • Vitamin D may have a key role in helping the brain to keep working well in later life • Vitamin D is linked to maintaining a healthy body weight • It can reduce the severity and frequency of asthma symptoms as well as the , and also the likelihood of hospitalizations due to asthma. • It has been shown to reduce the risk of developing rheumatoid arthritis in women. • A form of vitamin D could be one of our body's main protections against damage from low levels of radiation. • People with adequate levels of vitamin D have a significantly lower risk of developing cancer.